Patents by Inventor Ruth Raiss

Ruth Raiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives
    Patent number: 6387934
    Abstract: 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives are suitable for the production of pharmaceuticals for the prophylaxis and therapy of diseases or disorders whose course involves increased connective tissue or cartilage degradation.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: May 14, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wilfried Schwab, Ruth Raiss
  • 2-cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives
    Patent number: 6172103
    Abstract: 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives are suitable for the production of pharmaceuticals for the prophylaxis and therapy of diseases or disorders whose course involves increased connective tissue or cartilage degradation.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: January 9, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wilfried Schwab, Ruth Raiss
  • 2-cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives
    Patent number: 6121316
    Abstract: 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives ##STR1## are suitable for the production of pharmaceuticals for the prophylaxis and therapy of diseases or dissorders whose course involves increased connective tissue or cartilage degradation.
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: September 19, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Wilfried Schwab, Ruth Raiss
  • Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders
    Patent number: 5627173
    Abstract: Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders Compounds of the formula I ##STR1## are suitable for producing pharmaceuticals for the treatment and prophylaxis of degenerative joint disorders, of rheumatic disorders accompanied by cartilage breakdown, such as rheumatoid arthritis, joint trauma and chondrolysis as a consequence of prolonged immobilization of the joint, of inflammations, septic shock, disorders with impaired leukocyte adhesion, disorders caused by an elevated concentration of tumor necrosis factor alpha, such as cachexia or Crohn's disease.
    Type: Grant
    Filed: January 23, 1996
    Date of Patent: May 6, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rolf Graeve, Werner Thorwart, Ruth Raiss, Klaus U. Weithmann, Stefan M ullner
  • N-cycloalkylaminoethane-1,1-bis (phosphonic acid) useful for the treatment of osteoporosis and degenerative joint disease
    Patent number: 5364846
    Abstract: Substituted aminoethane-1,1-bisphosphonic acids and aminoethane-1,1-alkylphosphinophosphonic acids, processes for their preparation and use thereofThe invention relates to compounds of the formula I ##STR1## in which R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are a hydrogen atom or (C.sub.5 -C.sub.5)-alkyl, m is the integer 0 or 1, x is (C.sub.1 -C.sub.10)-alkyl, mono- or polysubstituted, a 5- or 6-membered ring having one nitrogen atom and optionally a further nitrogen or oxygen atom; aryl having 6 or 10 carbon atoms, which can be substituted; or cycloalkyl, to processes for the preparation of the compound of the formula I; to pharmaceuticals, and to their use for the treatment of osteoporosis and degenerative joint diseases.
    Type: Grant
    Filed: November 24, 1993
    Date of Patent: November 15, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans Lang, Christoph Naumann, Ruth Raiss, Osamu Komiyama, Yoshiko Terui