Patents by Inventor Ruth Siewe

Ruth Siewe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbial preparation of substances from aromatic metabolism/I
    Patent number: 6316232
    Abstract: The invention makes available, by means of an increased provision of intracellular metabolic intermediates, in particular of erythrose 4-phosphate, alternative processes for the microbial preparation of substances, in particular of aromatic amino acids such as L-phenylalanine, in which processes the activity of a transaldolase is increased in a microorganism producing these substances. In preferred embodiments of the invention, the activity of a transketolase or the activity of a transport protein for the PEP-independent uptake of a sugar and/or the activity of a kinase which phosporylates the relevant sugar are/is additionally increased. The invention also relates to gene structures, and to transformed cells carrying these gene structures, which make it possible to implement these processes in a particularly successful manner.
    Type: Grant
    Filed: April 26, 1999
    Date of Patent: November 13, 2001
    Assignees: Holland Sweetener Company V.O.F., Forschungszentrum Julich GmbH, DSM Biotech GmbH
    Inventors: Georg Sprenger, Ruth Siewe, Hermann Sahm, Martin Karutz, Theodorus Sonke