Patents by Inventor Ruth Thieroff-Ekerdt

Ruth Thieroff-Ekerdt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230338481
    Abstract: The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.
    Type: Application
    Filed: June 27, 2023
    Publication date: October 26, 2023
    Inventors: Devrim EREN, Ruth THIEROFF-EKERDT, Luigi BOLTRI, Vincenza PIRONTI, Letizia UBIGLIA
  • Publication number: 20220233577
    Abstract: Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for treating diseases associated with hyperammonemia, e.g., urea cycle disorders (UCD) and hepatic encephalopathy (HE), e.g., minimal HE (MHE) and overt HE (OHE), and modulating enzyme activities and levels of microbes and taxa, and metabolites (e.g., ammonia) in the microbiome of a subject.
    Type: Application
    Filed: November 3, 2018
    Publication date: July 28, 2022
    Inventors: Molly Krisann Gibson, Nathan Wilson Stebbins, Ruth Thieroff-Ekerdt, Geoffrey A. von Maltzahn
  • Publication number: 20220072009
    Abstract: Short-acting selective glucocorticoid receptor modulators for preventing, relieving or treating symptoms, disorders and diseases associated with acute stress or temporary hypercortisolism and compositions comprising immediate release and a plurality of delayed pulse releases of the modulators.
    Type: Application
    Filed: December 23, 2019
    Publication date: March 10, 2022
    Inventor: Ruth THIEROFF-EKERDT
  • Publication number: 20210283229
    Abstract: The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.
    Type: Application
    Filed: March 12, 2021
    Publication date: September 16, 2021
    Inventors: Devrim EREN, Ruth THIEROFF-EKERDT, Luigi BOLTRI, Vincenza PIRONTI, Letizia UBIGLIA
  • Patent number: 10993996
    Abstract: The present invention is directed to a digestive enzyme composition comprising an enterically coated digestive enzyme product, administrable nutritional medium, and a pharmaceutically acceptable low viscosity oily ingredient. The process for the preparation of the digestive enzyme composition comprises adding an enterically coated digestive enzyme product to a administrable nutritional medium and pharmaceutically acceptable low viscosity oily ingredient. The invention further provides a method for treating a patient suffering from exocrine pancreatic insufficiency related condition comprising administering to the patient a therapeutically effective dose of the digestive enzyme composition by means of a feeding tube.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: May 4, 2021
    Assignee: Allergan Pharmaceuticals International Limited
    Inventors: Devrim Eren, Ruth Thieroff-Ekerdt, Luigi Boltri, Vincenza Pironti, Letizia Ubliglia
  • Publication number: 20160051472
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Application
    Filed: June 5, 2014
    Publication date: February 25, 2016
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Publication number: 20140287035
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Patent number: 8784884
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: July 22, 2014
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Publication number: 20110064799
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Application
    Filed: September 28, 2009
    Publication date: March 17, 2011
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Publication number: 20110003005
    Abstract: Extended release ondansetron compositions of the present invention are useful for treating postoperative nausea and vomiting (PONV) and/or postdischarge nausea and vomiting (PDNV).
    Type: Application
    Filed: January 15, 2010
    Publication date: January 6, 2011
    Inventors: Gopi Venkatesh, Stephen Perrett, Ruth Thieroff-Ekerdt
  • Patent number: 7211680
    Abstract: Compounds of Formula I, wherein Y1, Y2, R1–R6, Q and Z are as defined herein, are vitamin D derivatives. These compounds are useful for, e.g., the treatment hyperprolifierative diseases of the skin, tumor diseases and precancerous stages, auto-immune diseases, rejection reactions in the case of autologous, allogenic or xenogenic transplants, AIDS, atopic skin conditions, secondary hyperparathyroidism, renal osteodystrophia, senile and postmenopausal osteoporosis, diabetes mellitus type II, degenerative diseases of the peripheral and central nervous system, hypercalcemias, granulomatous diseases, paraneoplastic hypercalcemias, hypercalcemias in hyperparathyroidism, hirsutism, ateriosclerosis, and/or inflammatory diseases.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: May 1, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Steinmeyer, Gerald Kirsch, Guenter Neef, Katiea Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
  • Publication number: 20050080058
    Abstract: Compounds of Formula I, wherein Y1, Y2, R1-R6, Q and Z are as defined herein, are vitamin D derivatives. These compounds are useful for, e.g., the treatment hyperprolifierative diseases of the skin, tumor diseases and precancerous stages, auto-immune diseases, rejection reactions in the case of autologous, allogenic or xenogenic transplants, AIDS, atopic skin conditions, secondary hyperparathyroidism, renal osteodystrophia, senile and postmenopausal osteoporosis, diabetes mellitus type II, degenerative diseases of the peripheral and central nervous system, hypercalcemias, granulomatous diseases, paraneoplastic hypercalcemias, hypercalcemias in hyperparathyroidism, hirsutism, ateriosclerosis, and/or inflammatory diseases.
    Type: Application
    Filed: September 10, 2003
    Publication date: April 14, 2005
    Applicant: Schering Aktiengesellschaft Patents
    Inventors: Andreas Steinmeyer, Gerald Kirsch, Gunter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
  • Patent number: 6642218
    Abstract: The invention relates to vitamin D derivatives of formula (I), processes for the production thereof and uses thereof: wherein Y1, Y2, R1-R6, Q and Z are as defined herein.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: November 4, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Steinmeyer, Gerald Kirsch, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
  • Patent number: 6613920
    Abstract: The invention relates to vitamin D derivatives of formula (I), processes for the production thereof and uses thereof: wherein Y1, Y2, R1—R6, Q and Z are as defined herein.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: September 2, 2003
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Steinmeyer, Gerald Kirsch, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
  • Patent number: 6600058
    Abstract: The invention concerns new vitamin D derivatives of general formula (I) a process for their production, their use for production of medicaments, and intermediate products used in the process.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: July 29, 2003
    Assignee: Schering Aktiengellschaft
    Inventors: Andreas Steinmeyer, Gerald Kirsch, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey, Marianne Fahnrich
  • Publication number: 20020049344
    Abstract: The invention concerns new vitamin D derivatives of general formula (I) a process for their production, their use for production of medicaments, and intermediate products used in the process.
    Type: Application
    Filed: December 11, 1998
    Publication date: April 25, 2002
    Inventors: ANDREAS STEINMEYER, GERALD KIRSCH, GUNTER NEFF, KATICA SCHWARZ, RUTH THIEROFF-EKERDT, HERBERT WIESINGER, MARTIN HABEREY, MARIANNE FAHNRICH
  • Patent number: 6376480
    Abstract: A method of preparing a pharmaceutical composition, comprising combining a pharmaceutically compatible vehicle with a compound according to formula (I)
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: April 23, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerald Kirsch, Andreas Steinmeyer, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Andreas Menrad, Martin Haberey
  • Patent number: 6372731
    Abstract: A vitamin D derivative and its uses with substituents at C-25 of general formula I
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: April 16, 2002
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerald Kirsch, Andreas Steinmeyer, Günter Neef, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Andreas Menrad, Martin Haberey
  • Patent number: 5700791
    Abstract: The invention relates to vitamin D derivatives, modified in 20-position, of general formula I ##STR1## in which X, Y, Z, R.sub.1, R.sub.2 as well as R.sub.3 have the meaning indicated in the description, process for their production and their use as agents for treatment of hyperproliferative diseases of the skin.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: December 23, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Andreas Steinmeyer, Gunter Neef, Gerald Kirsch, Katica Schwarz, Ruth Thieroff-Ekerdt, Herbert Wiesinger, Martin Haberey
  • Patent number: 5665716
    Abstract: New 24-homo vitamin D derivatives of formula I ##STR1## are described, in which R.sup.1 means a hydrogen atom, a hydroxy, an alkanoyloxy group with 1 to 8 carbon atoms or an aralkanoyloxy group with up to 8 carbon atoms,R.sup.2 and R.sup.3, independently of one another, mean a linear or branched alkyl group with 1 to 4 carbon atoms, a trifluoromethyl group or together mean a saturated carbocyclic ring with 3 to 9 carbon atoms formed with carbon atom 25,R.sup.4 and R.sup.5, independently of one another, mean a hydrogen atom, an alkanoyl group with 1 to 8 carbon atoms or an aralkanoyl group with up to 8 carbon atoms, andA and B each mean a hydrogen or together a second bond, andn stands for 1, 2, 3,4 or 5.
    Type: Grant
    Filed: October 2, 1990
    Date of Patent: September 9, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerald Kirsch, Gunter Neef, Katicia Schwarz, Matthias Brautigam, Ruth Thieroff-Ekerdt, Petra Rach