Patents by Inventor Ruth Wei Aranda

Ruth Wei Aranda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPIES
    Publication number: 20220096482
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a CDK 4/6 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: March 31, 2022
    Inventors: James Gail Christensen, Ruth Wei Aranda, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220079947
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SHP-2 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: December 5, 2019
    Publication date: March 17, 2022
    Inventors: James Gail Christensen, Lars Daniel Engstrom, Peter Olson, Ruth Wei Aranda
  • COMBINATION THERAPIES
    Publication number: 20220054491
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a pan ErbB family inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: February 24, 2022
    Inventors: James Gail Christensen, Lars Daniel Engstrom, Ruth Wei Aranda, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220054492
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Raf family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 10, 2019
    Publication date: February 24, 2022
    Inventors: Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220040182
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a mTOR inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 10, 2019
    Publication date: February 10, 2022
    Inventors: Peter Olson, Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin
  • COMBINATION THERAPIES
    Publication number: 20220040181
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Src-family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: February 10, 2022
    Inventors: Lars Daniel Engstrom, Ruth Wei Aranda, Peter Olson, James Gail Christensen