Patents by Inventor Ruth Weis

Ruth Weis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPIES
    Publication number: 20250108055
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Raf family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: October 3, 2024
    Publication date: April 3, 2025
    Inventors: Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • Combination therapies
    Patent number: 12208099
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Raf family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: January 28, 2025
    Assignee: Mirati Therapeutics, Inc.
    Inventors: Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220096482
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a CDK 4/6 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: March 31, 2022
    Inventors: James Gail Christensen, Ruth Wei Aranda, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220079947
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SHP-2 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: December 5, 2019
    Publication date: March 17, 2022
    Inventors: James Gail Christensen, Lars Daniel Engstrom, Peter Olson, Ruth Wei Aranda
  • COMBINATION THERAPIES
    Publication number: 20220054491
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a pan ErbB family inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: February 24, 2022
    Inventors: James Gail Christensen, Lars Daniel Engstrom, Ruth Wei Aranda, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220054492
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Raf family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula (I-A) or Formula (I-B), pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 10, 2019
    Publication date: February 24, 2022
    Inventors: Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin, Peter Olson
  • COMBINATION THERAPIES
    Publication number: 20220040181
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a Src-family kinase inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 9, 2019
    Publication date: February 10, 2022
    Inventors: Lars Daniel Engstrom, Ruth Wei Aranda, Peter Olson, James Gail Christensen
  • COMBINATION THERAPIES
    Publication number: 20220040182
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a mTOR inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
    Type: Application
    Filed: September 10, 2019
    Publication date: February 10, 2022
    Inventors: Peter Olson, Ruth Wei Aranda, James Gail Christensen, Lars Daniel Engstrom, Jill Hallin
  • Effervescent bath tablet, method of preparing it, and the use thereof
    Patent number: 6565881
    Abstract: The present invention relates to a new type of solid balneological preparations for cosmetic, hygienic and therapeutic use, which has both the properties of a solid bath additive and those of liquid products, and is characterized especially by the addition of lipid components, vesicle forming lipids, tensides and, in some cases, mineral salts. Active components, adjuvants such as stabilizers, adsorbing substances, lubricants as well as smoothing and breakdown promoting agents may also be contained therein.
    Type: Grant
    Filed: July 13, 1998
    Date of Patent: May 20, 2003
    Assignee: Marz Pharma GmbH & Co.KgaA
    Inventors: Eberhard Nürnberg, Kerstin Jerzembek, Rolf D. Beutler, Jürgen Ebinger, Ruth Weis
  • Effervescent bath tablet, method of preparing it, and the use thereof
    Patent number: 6197338
    Abstract: The present invention relates to a new type of solid balneological preparations for cosmetic, hygienic and therapeutic use, which has both the properties of a solid bath additive and those of liquid products, and is characterized especially by the addition of lipid components, vesicle forming lipids, tensides and, in some cases, mineral salts. Active components, adjuvants such as stabilizers, adsorbing substances, lubricants as well as smoothing and breakdown promoting agents may also be contained therein.
    Type: Grant
    Filed: January 12, 2000
    Date of Patent: March 6, 2001
    Assignee: Merz & Co. GmbH & Co.
    Inventors: Eberhard Nürnberg, Kerstin Jerzembek, Rolf D. Beutler, Jürgen Ebinger, Ruth Weis