Patents by Inventor Rutuja Sudhakar Pai

Rutuja Sudhakar Pai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS
    Publication number: 20240360451
    Abstract: Described herein are methods of modulating OTC gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for increasing expression of Ornithine transcarbamylase (OTC), thereby treating diseases associated with aberrant gene expression.
    Type: Application
    Filed: September 2, 2022
    Publication date: October 31, 2024
    Inventors: Alfica Sehgal, Bryan J. Matthews, Cynthia M. Smith, David A. Bumcrot, Justin A. Caravella, Mario Esteban Contreras Gamboa, Rachana S. Kelkar, Yun Joon Jung, Yuting Liu, Subhadeep Roy, Brynn Nicole-Yoshiko Akerberg, Rutuja Sudhakar Pai
  • MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS
    Publication number: 20240336924
    Abstract: Described herein are methods of modulating gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for modulating the levels of gene products, for example, increasing expression of Carbamoyl-Phosphatase Synthetase 1 (CPS1), thereby treating diseases associated with aberrant gene expression.
    Type: Application
    Filed: June 24, 2024
    Publication date: October 10, 2024
    Inventors: Alfica Sehgal, Bryan J. Matthews, David A. Bumcrot, Justin A. Caravella, Mario Esteban Contreras Gamboa, Rachana S. Kelkar, Yun Joon Jung, Yuting Liu, Rutuja Sudhakar Pai, Henry Munir Moukheiber, Subhadeep Roy, Yuchun Guo