Patents by Inventor Ruud Luiten

Ruud Luiten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • -hydroxynitrillyases having improved substrate tolerance and the use thereof
    Patent number: 7572608
    Abstract: The invention relates to R-hydroxynitrillyases from the family of Rosaceae that are characterized by an improved substrate tolerance and increased stability. In the active center of the R-hydroxynitrillyases either a) an alanine group is substituted by glycine, valine, leucine, isoleucine, or phenylalanine or b) a phenylalanine group is substituted by alanine, glycine valine, leucine or isoleucine, or c) a leucine group is substituted by alanine, glycine, valine, isoleucine or phenylalanine, or d) an isoleucine group is substituted by alanine, glycine, valine, leucine or phenylalanine. The invention also relates to the use of these lyases in the production of enantiomer-pure R- or S-cyanohydrines.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: August 11, 2009
    Assignee: DSM Fine Chemicals Austria NFG GmbH & Co. KG
    Inventors: Wolfgang Skranc, Anton Glieder, Karl Gruber, Roland Weis, Ruud Luiten
  • R-hydroxynitrillyases havign improved substrate tolerance and the use thereof
    Publication number: 20060105434
    Abstract: The invention related to R-hydroxynitrillyases from the family of Rosaceae that are characterized by an improved substrate tolerance and increased stability. In the active center of the R-hydroxynitrillyases either a) an alanine group is substituted by glycine, valine, leucine, isoleucine, or phenylalanine or b) a phenylalanine group is substituted by alanine, glycine valine, leucine or isoleucine, or c) a leucine group is substituted by alanine, glycine, valine, isoleucine or phenylalanine, or d) an isoleucine group is substituted by alanine, glycine, valine, leucine or phenylalanine. The invention also relates to the use of these lyases in the production of enantiomer-pure R- or S-cyanohydrines.
    Type: Application
    Filed: February 24, 2004
    Publication date: May 18, 2006
    Inventors: Wolfgang Skranc, Anton Glieder, Karl Gruber, Roland Weis, Ruud Luiten