Patents by Inventor Ruyun Zhou

Ruyun Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11951116
    Abstract: A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: April 9, 2024
    Assignee: SINGAPORE ZE&ZINTERNATIONAL PTE. LTD
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Publication number: 20210077516
    Abstract: A method of treating or preventing a vaginal disease and/or a vaginal discomfort in a patient in need thereof, the method comprising administering a vaginal composition comprising isomaltulose to the vagina of the patient to restore and/or maintain Lactobacilli in the vagina, and/or to restore and/or maintain the vaginal acidity, wherein the content of the isomaltulose ranges from 0.05% (w/w) to 20.0% (w/w).
    Type: Application
    Filed: December 1, 2020
    Publication date: March 18, 2021
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Patent number: 10869878
    Abstract: A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: December 22, 2020
    Assignee: SINGAPORE ZE&Z INTERNATIONAL PTE. LTD
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Publication number: 20160375045
    Abstract: A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.
    Type: Application
    Filed: September 12, 2016
    Publication date: December 29, 2016
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Patent number: 8765819
    Abstract: The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: July 1, 2014
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Patent number: 8586549
    Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: November 19, 2013
    Assignees: Shenzhen Phlora Biotechnology Limited, HK Phlora Health Sci & Tech. Limited
    Inventors: Ruyun Zhou, Zhongming Zeng
  • Publication number: 20120263667
    Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.
    Type: Application
    Filed: June 29, 2012
    Publication date: October 18, 2012
    Applicants: HK PHLORA HEALTH SCI. & TECH. LIMITED, SHENZHEN PHLORA BIOTECHNOLOGY LIMITED
    Inventors: Ruyun ZHOU, Zhongming ZENG
  • Publication number: 20120245132
    Abstract: The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.
    Type: Application
    Filed: October 8, 2010
    Publication date: September 27, 2012
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Publication number: 20080193428
    Abstract: The present invention relates to the use of benzoic acid and/or its sodium salt in combination with saccharide(s) as active components in the manufacture of a vaginal composition for modulating vaginal flora and vaginal acidity, thereby maintaining the pH value of vaginal secretion within a range from 3.5 to 4.5; and the present invention further relates to a vaginal composition and a method for modulating and maintaining normal vaginal flora and vaginal acidity.
    Type: Application
    Filed: April 27, 2006
    Publication date: August 14, 2008
    Applicants: Shenzhen Phlora Biotechnology Limited, HK Phlora Health Science & Technology Ltd.
    Inventors: Ruyun Zhou, Zhongming Zeng