Patents by Inventor Ryan A. Dick

Ryan A. Dick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioactivation of alkylating agents for cancer treatment
    Patent number: 7718385
    Abstract: A rapid screening method for identifying acylfulvenes and acylfulvene analogs with improved chemotherapeutic properties has been developed. The mechanism of toxicity of irofulven, a potentially clinically useful member of the acylfulvene class, has been elucidated and provides guidance for design and testing of a new class of alkylating agents with structures related to irofulven. The role of alkenal/one oxidoreductase (AOR) is shown to be important in cancer cell susceptibility to this class of alkylating agent.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: May 18, 2010
    Assignee: The Johns Hopkins University
    Inventor: Ryan A. Dick