Patents by Inventor Ryan Beal
Ryan Beal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210369769Abstract: Provided herein are formulations for the safe and effective topical delivery of buffering agents. The invention includes formulations and methods to balance electrolytes, overcome cation overload, and/or deliver buffers with and without counterions that can be combined in a single use formulation or alternatively in separately applied formulations. Also provided are methods of using the formulations for the treatment of a wide variety of disorders relating to electrolyte imbalance, cation overload, or related conditions.Type: ApplicationFiled: November 6, 2019Publication date: December 2, 2021Applicant: DYVE BIOSCIENCES, INC.Inventors: Ryan Beal, Luke Gonzales, Kilmar Martinez, Brandon Sand, Lisa Misell, Nathan Fitzsimmons
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Publication number: 20210338613Abstract: A formulation for transdermal delivery of one or more ketone components through the skin of a subject, comprising: a ketone component in an amount between about 10-60% w/w; a penetrant portion in an amount less than about 60% w/w, and water in an amount less than about 50% w/w.Type: ApplicationFiled: October 6, 2019Publication date: November 4, 2021Applicant: DYVE BIOSCIENCES, INC.Inventors: Ryan Beal, Luke Gonzales, Kilmar Martinez, Brandon Sand, Lisa Misell, Nathan Fitzsimmons
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Publication number: 20210268122Abstract: Two disparate biological mechanisms which predispose to the dissemination and metastases of solid tumors is described.Type: ApplicationFiled: March 2, 2021Publication date: September 2, 2021Applicant: DYVE BIOSCIENCES, INC.Inventors: Ryan Beal, Bruce Sand, Seth Brunner, Brandon Sand, Kilmar Martinez, Luke Gonzales, Lisa Misell, Nathan Fitzsimmons
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Publication number: 20210228623Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: February 4, 2021Publication date: July 29, 2021Applicant: DYVE BIOSCIENCES, INC.Inventor: Ryan Beal
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Patent number: 11026896Abstract: Disclosed herein is a transdermal delivery formulation for transdermal delivery of a Cannabidiol, with or without one or more additional active agents through the dermis, including the skin, nail or hair follicle of a subject, wherein the formulation comprises a) a transdermal delivery formulation in an amount less than about 60% w/w, comprising i. one or more phosphatides, ii. glucose, and iii. one or more fatty acids; b) water in an amount less than about 50% w/w, a Cannabidiol with or within one or more additional active agents.Type: GrantFiled: August 20, 2019Date of Patent: June 8, 2021Assignee: DYVE BIOSCIENCES, INC.Inventors: Nathan Fitzsimmons, Ryan Beal, Audrene McMahon, Brandon Sand, Kilmar Martinez
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Publication number: 20210154226Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: February 4, 2021Publication date: May 27, 2021Applicant: DYVE BIOSCIENCES, INC.Inventor: Ryan Beal
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Patent number: 10933088Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: GrantFiled: May 4, 2020Date of Patent: March 2, 2021Assignee: DYVE BIOSCIENCES, INC.Inventor: Ryan Beal
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Publication number: 20200397716Abstract: Disclosed herein is a transdermal delivery formulation for transdermal delivery of a Cannabidiol, with or without one or more additional active agents through the dermis, including the skin, nail or hair follicle of a subject, wherein the formulation comprises a) a transdermal delivery formulation in an amount less than about 60% w/w, comprising i. one or more phosphatides, ii. glucose, and iii. one or more fatty acids; b) water in an amount less than about 50% w/w, a Cannabidiol with or within one or more additional active agents.Type: ApplicationFiled: August 20, 2019Publication date: December 24, 2020Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventors: Nathan Fitzsimmons, Ryan Beal, Audrene McMahon, Brandon Sand, Kilmar Martinez
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Patent number: 10842758Abstract: Disclosed herein is a transdermal delivery formulation for transdermal delivery of a Cannabidiol, with or without one or more additional active agents through the dermis, including the skin, nail or hair follicle of a subject, wherein the formulation comprises a) a transdermal delivery formulation in an amount less than about 60% w/w, comprising i. one or more phosphatides, ii. glucose, and iii. one or more fatty acids; b) water in an amount less than about 50% w/w, a Cannabidiol with or within one or more additional active agents.Type: GrantFiled: August 20, 2019Date of Patent: November 24, 2020Assignee: AMPERSAND BIOPHARMACEUTICALS, INC.Inventors: Nathan Fitzsimmons, Ryan Beal, Audrene McMahon, Brandon Sand, Kilmar Martinez
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Publication number: 20200330506Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: May 4, 2020Publication date: October 22, 2020Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventor: Ryan Beal
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Patent number: 10639326Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: GrantFiled: August 20, 2019Date of Patent: May 5, 2020Assignee: AMPERSAND BIOPHARMACEUTICALS, INC.Inventor: Ryan Beal
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Patent number: 10632146Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: GrantFiled: August 20, 2019Date of Patent: April 28, 2020Assignee: AMPERSAND BIOPHARMACEUTICALS, INC.Inventor: Ryan Beal
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Publication number: 20200030371Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: August 20, 2019Publication date: January 30, 2020Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventor: Ryan Beal
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Publication number: 20190365798Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid tumors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: August 20, 2019Publication date: December 5, 2019Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventor: Ryan Beal
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Publication number: 20190134219Abstract: Two disparate biological mechanisms which predispose to the dissemination and metastases of solid tumors is described.Type: ApplicationFiled: September 15, 2018Publication date: May 9, 2019Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventors: Ryan Beal, Bruce Sand, Seth Brunner, Brandon Sand, Kilmar Martinez, Luke Gonzales, Lisa Misell, Nathan Fitzsimmons
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Publication number: 20190083527Abstract: Provided herein are formulations for topical and/or transdermal administration, and methods of using these formulations for the treatment of proliferative diseases related to cancer such as cancers and related conditions, and solid minors. Also provided are formulations for topical and/or transdermal administration, and methods of using these formulations for melasma, gout, skin disorders, and other diseases and disorders described herein as well as methods for modulating the pH (e.g. raising) of a tissue or microenvironment proximal to a tumor, modulating pH, or improving the effectiveness of know chemotherapeutic agents, immunotherapy and the like for the prevention, treatment of cancers and related conditions described herein.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventors: Ryan Beal, Seth Brunner, Bruce Sand, Jeff Byers, Lisa Misell, Nathan Fitzsimmons, Brandon Sand, Kilmar Martinez, Luke Gonzales
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Publication number: 20190083386Abstract: A formulation for transdermal delivery of one or more buffering agents through the skin of a subject, comprising: a buffering agent comprising at least one carbonate salt, lysine, tris, a phosphate buffer and/or 2-imidazole-1-yl-3-ethoxycarbonylpropionic acid (IEPA), or a combination thereof in an amount between about 10-56% w/w; and a penetrant portion in an amount between about 44 to 90% w/w, wherein the penetrant portion comprises water in an amount less than about 85% w/w, and wherein the formulation comprises less than about 12% w/w lecithin.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Applicant: AMPERSAND BIOPHARMACEUTICALS, INC.Inventors: Seth Brunner, Ryan Beal, Bruce Sand, Brandon Sand, Kilmar Martinez, Luke Gonzales
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Patent number: D727321Type: GrantFiled: September 21, 2012Date of Patent: April 21, 2015Assignee: RF Technologies, Inc.Inventors: John LaBorde, Paul Larson, Mary Van Himbergen, Erik Stabl, Nasseim Bleibel, Michelle Dalton, Ryan Beal
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Patent number: D736738Type: GrantFiled: September 21, 2012Date of Patent: August 18, 2015Assignee: RF Technologies, Inc.Inventors: Paul Larson, John LaBorde, Mary Van Himbergen, Erik Stabl, Nasseim Bleibel, Michelle Dalton, Ron Kosek, Ryan Beal
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Patent number: D772837Type: GrantFiled: July 10, 2015Date of Patent: November 29, 2016Assignee: RF Technologies, Inc.Inventors: Paul Larson, John LaBorde, Mary Van Himbergen, Erik Stabl, Nasseim Bleibel, Michelle Dalton, Ron Kosek, Ryan Beal