Patents by Inventor Ryan C. Fink

Ryan C. Fink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuated FNR deficient enterobacteria
    Patent number: 8435506
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: May 7, 2013
    Assignee: North Carolina State University
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • ATTENUATED FNR DEFICIENT ENTEROBACTERIA
    Publication number: 20120128718
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Application
    Filed: December 15, 2011
    Publication date: May 24, 2012
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • Attenuated FNR deficient enterobacteria
    Patent number: 8101168
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: January 24, 2012
    Assignee: North Carolina State University
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans
  • ATTENUATED FNR DEFICIENT ENTEROBACTERIA
    Publication number: 20100255036
    Abstract: The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen. Also provided are pharmaceutical formulations comprising the attenuated enterobacteria of the invention. Further disclosed are methods of inducing an immune response in a subject by administration of an immunogenically effective amount of an attenuated enterobacterium or pharmaceutical formulation of the invention.
    Type: Application
    Filed: July 9, 2009
    Publication date: October 7, 2010
    Inventors: Hosni M. Hassan, Ryan C. Fink, Matthew R. Evans