Abstract: A method for providing biofeedback to a user may include receiving a first signal associated with one or more biometric properties of a user, and determining a baseline cognitive state of the user based on the first signal. The method may include iteratively detecting an instant cognitive state of the user, and receiving, from the detecting step, a second signal associated with the one or more biometric properties. The method may include determining whether the second signal corresponds to threshold(s). Responsive to such determination, the method may include initiating first feedback action(s). Responsive to initiating the first feedback action(s), the method may include determining whether the instant cognitive state of the user is between the threshold(s) and the baseline cognitive state, and if not, initiating second feedback action(s).

Abstract: A system may include a substrate in contact with a user. The substrate may include first detector(s) capable of detecting optical biometric properties of the user, and second detector(s) capable of detecting non-optical biometric properties of the user. The system may include a first and a second electronics module communicatively coupled to the substrate. Each of the two electronics modules may include a processor, a memory device, and instructions stored on the memory device that, when executed, direct the processor to perform step(s). These step(s) may include receiving a signal from the first detector(s) or second detector(s), processing the signal based on predefined algorithm(s), and determining, based on the processed signal, whether the user requires one or more feedback actions.

Abstract: Described are systems and methods that suggest candidate recipients to receive an object identifier from a first user. For example, a first user, independent of a conversation with a second user, may select, close-up, or otherwise view an object identifier. The system, upon detecting the interaction with the object identifier by the first user, may determine one or more second users to suggest to the first user as candidate recipients with which the first user can share the viewed object identifier. The systems and methods may also suggest object identifiers to share with a selected recipient and/or determine two or more users that have a common connection and share an object identifier related to the connection with each of those users.

Abstract: The present disclosure provides a tissue-removing catheter for removing tissue in a body lumen. The tissue-removing catheter includes an elongate drive member and a tissue-removing element. The elongate drive member has proximal and distal ends with a length and a longitudinal axis extending between the proximal and distal ends. The elongate drive member is sized and shaped to be received in the body lumen and rotates about its longitudinal axis. The elongate drive member further includes first and second longitudinal portions. The first longitudinal portion is proximal to and stiffer than the second longitudinal portion. The tissue-removing element is operatively coupled to the distal end of the elongate drive member and rotates by the elongate drive member to remove the tissue in the body lumen.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: A near-infrared spectroscopy system for monitoring human physiology in activities related to aircraft comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: This disclosure provides a wearable point-of-care (POC) device for assessing immune activity in a subject in need thereof, the device comprising: a microneedle patch capable of making conformal contact with a skin of the subject, the microneedle patch comprising a plurality of microneedles: a lateral flow test strip comprising a plurality of channels, each of the channels in the plurality of channels comprising control and capture antibodies for an analyte in a plurality of analytes, wherein the control and capture antibodies are deposited along a length of the channel such that upon exposure to the analyte a number of visible spots in the channel is correlated with a concentration of the analyte; and a means for pumping an interstitial fluid from the plurality of microneedles and through each of the channels in the plurality of channels when the device is on the skin of the subject.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: A cartridge assembly for selective connection to a surgical stapling apparatus includes a body portion, a tissue contact surface defining staple retention slots, staples, a collar assembly and a staple sheath. Each of the staples is received in a respective one of the staple retention slots of the tissue contact surface. The collar assembly is movably mounted to the body portion. The staple sheath is coupled to the collar assembly and positioned to cover the staple retention slots. The staple sheath is selectively movable relative to the tissue contact surface.

Abstract: The invention provides methods and kits for detecting the presence of, the amount of, or the concentration of a substantially non-emitting metal in a sample by a) providing a sensitizer to a chelator of the substantially non-emitting metal thereby creating a sensitized-metal complex; b) adding an unsensitized chelate, and c) detecting a signal from the unsensitized chelate. The substantially non-emitting metal may be gadoliniumn and may exist in complex with a chelator. The unsensitized chelate may be terbium (Tb) or europium (Eu) and the detecting a signal may be performed by fluorescence.

Abstract: In particular embodiments, a system includes a processor operable to receive, from a client device, a user selection of 360-degree media content to display on a display device that is separate from the client device. The processor is further operable to provide the selected 360-degree media content for display on the display device. The processor is further operable to receive motion data from the client device, the motion data indicating motion of the client device. The processor is further operable to provide instructions to adjust a viewing direction within the 360-degree media content displayed on the display device according to the received motion data from the client device.

Abstract: The invention provides methods and kits for detecting the presence of, the amount of, or the concentration of a substantially non-emitting metal in a sample by a) providing a sensitizer to a chelator of the substantially non-emitting metal thereby creating a sensitized-metal complex; b) adding an unsensitized chelate, and c) detecting a signal from the unsensitized chelate. The substantially non-emitting metal may be gadoliniumn and may exist in complex with a chelator. The unsensitized chelate may be terbium (Tb) or europium (Eu) and the detecting a signal may be performed by fluorescence.

Abstract: In particular embodiments, a system includes a processor operable to receive, from a client device, a user selection of video content to display on a display device that is separate from the client device. The processor is further operable to receive a first user input on a touch-sensitive portion of the client device. The processor is further operable to display, in response to the first user input, a plurality of selectable reactions overlaid on the selected video being displayed on the display device. The processor is further operable to receive a second user input to select one of the selectable reactions. The processor is further operable to display, in response to the second user input, a graphical representation of the selected reaction on the display device, the graphical representation being overlaid on the selected video being displayed on the display device.

Abstract: In particular embodiments, a system includes a processor operable to receive, from a client device, a user selection of 360-degree media content to display on a display device that is separate from the client device. The processor is further operable to provide the selected 360-degree media content for display on the display device. The processor is further operable to receive motion data from the client device, the motion data indicating motion of the client device. The processor is further operable to provide instructions to adjust a viewing direction within the 360-degree media content displayed on the display device according to the received motion data from the client device.

Abstract: An e-book system receives and stores different versions of an e-book supporting different consumption modes. Additionally, the e-book system stores signposts for the e-book. The signposts include corresponding locations in different versions of the e-book. When a user switches from a first version to a second version, the e-book system determines based on the signposts a location in the second version of the e-book that corresponds to the current location in the first version. The e-book system then presents the content in the second version from the determined location.

Abstract: A cartridge assembly for selective connection to a surgical stapling apparatus includes a body portion, a tissue contact surface defining staple retention slots, staples, a collar assembly and a staple sheath. Each of the staples is received in a respective one of the staple retention slots of the tissue contact surface. The collar assembly is movably mounted to the body portion. The staple sheath is coupled to the collar assembly and positioned to cover the staple retention slots. The staple sheath is selectively movable relative to the tissue contact surface.

Abstract: An e-book system receives and stores different versions of an e-book supporting different consumption modes. Additionally, the e-book system stores signposts for the e-book. The signposts include corresponding locations in different versions of the e-book. When a user switches from a first version to a second version, the e-book system determines based on the signposts a location in the second version of the e-book that corresponds to the current location in the first version. The e-book system then presents the content in the second version from the determined location.