Patents by Inventor Ryan D. Chow

Ryan D. Chow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS COMPRISING VIRAL VECTOR SYSTEMS FOR MULTIPLEXED ACTIVATION OF ENDOGENOUS GENES AS IMMUNOTHERAPY AND VIRAL-BASED IMMUNE-GENE THERAPY
    Publication number: 20220387626
    Abstract: The present invention includes compositions and methods comprising viral vector systems for multiplexed activation of endogenous genes as immunotherapy and viral-based immune-gene therapy.
    Type: Application
    Filed: October 23, 2020
    Publication date: December 8, 2022
    Inventors: Sidi CHEN, Guangchuan WANG, Ryan D. CHOW, Feifei ZHANG
  • Compositions and Methods for Identification of Membrane Targets for Enhancement of T cell Activity Against Cancer
    Publication number: 20220340898
    Abstract: The present invention includes compositions and methods for identification of membrane targets for enhancement of T cell activity against a disease, disorder or condition, and/or enhancing T cell anti-tumor activity in a subject in need thereof. In some embodiments, the disease is cancer. In further embodiments, the cancer is glioblastoma (GBM) or breast cancer.
    Type: Application
    Filed: July 31, 2019
    Publication date: October 27, 2022
    Inventors: Sidi Chen, Lupeng Ye, Jonathan Park, Matthew Dong, Ryan D. Chow
  • Compositions and Methods for High-Throughput Activation Screening to Boost T Cell Effector Function
    Publication number: 20210269794
    Abstract: The present invention includes dead-guide RNA (dgRNA) libraries and methods of use in immunology and immunotherapy thereof. Also provided are engineered primary or chimeric antigen receptor (CAR) T cells that overexpress Prodh2, Ccnblip1, Sreklip1, or Wdr37or a fragment thereof, and methods of use in immunology and immunothereapy thereof.
    Type: Application
    Filed: August 15, 2019
    Publication date: September 2, 2021
    Inventors: Sidi Chen, Ryan D. Chow, Lupeng Ye, Matthew Dong, Jonathan Park, Lei Peng
  • COMPOSITIONS AND METHODS FOR MULTIPLEXED TUMOR VACCINATION WITH ENDOGENOUS GENE ACTIVATION
    Publication number: 20210113674
    Abstract: The present invention includes compositions and methods for treating or preventing cancer. Embodiments include cell-based and viral vector-based vaccines that utilize gene expression activation systems to augment the product of endogenous genes to treat or prevent cancer.
    Type: Application
    Filed: April 17, 2019
    Publication date: April 22, 2021
    Inventors: Sidi Chen, Ryan D. Chow, Guangchuan Wang