Patents by Inventor Ryan Dellinger

Ryan Dellinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of nicotinamide riboside, nicotinic acid riboside, and nicotinamide mononucleotide, reduced nicotinyl compounds, and nicotinoyl compound derivatives in infant formula for healthy development
    Patent number: 12433908
    Abstract: Infant formula compositions and methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: October 7, 2025
    Assignee: ChromaDex Inc.
    Inventors: Ryan Dellinger, Troy Rhonemus, Mark Morris, Dietrich Conze, Amy Boileau
  • DEACYLATION OF CARBOHYDRATE COMPOUNDS
    Publication number: 20250171482
    Abstract: Compositions of de-acylated carbohydrate compounds and methods of making them are provided. The methods can be designed to produce the desired products under conditions of moderate temperature, moderate pH, and without the use of harsh solvents.
    Type: Application
    Filed: March 10, 2023
    Publication date: May 29, 2025
    Inventors: Ryan DELLINGER, Marie MIGAUD, Jyothi DHUGURU
  • RIBOSE LINKERS AND CONJUGATES THEREOF
    Publication number: 20250127804
    Abstract: The present disclosure provides a compound of Formula I: A-R1-A? wherein A and A? are independently H or [Formula I], wherein A, A?, and R1 are as described herein. Also provided are methods of making the compounds described herein, and use of the compounds, e.g., in NAD-increasing compositions.
    Type: Application
    Filed: February 3, 2023
    Publication date: April 24, 2025
    Inventors: Ryan DELLINGER, Marie MIGAUD, Jyothi DHUGURU
  • METHODS FOR TREATMENT OF MENOPAUSAL SYNDROMES
    Publication number: 20240415862
    Abstract: The present application provides methods for reducing the severity or frequency of menopausal symptoms by administering (a) a therapeutically effective amount of nicotinamide riboside, nicotinamide mononucleotide, nicotinamide, nicotinic acid, the reduced form of nicotinamide riboside (NRH), or a mixture thereof, and (b) a therapeutically effective amount of pterostilbene. The compositions can be administered orally or via other suitable administration routes.
    Type: Application
    Filed: October 12, 2022
    Publication date: December 19, 2024
    Inventors: Ryan DELLINGER, Marie MIGAUD
  • Nicotinamide riboside for use in treating or preventing liver damage
    Patent number: 12128060
    Abstract: Provided herein are methods and compositions related to treating and/or preventing liver related diseases and disorders and for improving liver health in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Grant
    Filed: June 16, 2022
    Date of Patent: October 29, 2024
    Assignee: Elysium Health, Inc.
    Inventors: Ryan Dellinger, Santiago Roel Santos, Eric A. Marcotulli, Daniel A. Alminana, Mark Morris, Leonard Pershing Guarente
  • Crystalline forms of nicotinamide riboside chloride
    Patent number: 12043616
    Abstract: Provided herein are crystalline forms of nicotinamide riboside chloride and methods of making the same. Also provided are compositions comprising the crystalline form of nicotinamide riboside chloride, and therapeutic methods employing the crystalline form of nicotinamide riboside chloride.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: July 23, 2024
    Assignee: Elysium Health, Inc.
    Inventors: Eric Marcotulli, Dan Alminana, Ryan Dellinger, Mark Morris
  • METHODS OF SYNTHESIZING NICOTINAMIDE RIBOSIDE
    Publication number: 20230348521
    Abstract: Provided herein are efficient and scalable methods for the synthesis of nicotinamide riboside from riboside triacetate. Also provided are compositions comprising nicotinamide riboside, and therapeutic methods employing nicotinamide riboside.
    Type: Application
    Filed: April 5, 2023
    Publication date: November 2, 2023
    Inventors: Eric Marcotulli, Dan Alminana, Ryan Dellinger, Mark Morris, Rajesh Thamatam
  • Treating and preventing motor neuron diseases using nicotinamide riboside
    Patent number: 11730751
    Abstract: Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: August 22, 2023
    Assignees: UNIVERSITAT DE VALÈNCIA-ESTUDI GENERAL, FUNDACIÓN UNIVERSIDAD CATÓLICA DE VALENCIA SAN VICENTE MÁRTIR, Elysium Health, Inc.
    Inventors: José Maria Estrela Ariguel, José Enrique De La Rubia Orti, Ryan Dellinger
  • USE OF NICOTINAMIDE RIBOSIDE, NICOTINIC ACID RIBOSIDE, AND NICOTINAMIDE MONONUCLEOTIDE, REDUCED NICOTINYL COMPOUNDS, AND NICOTINOYL COMPOUND DERIVATIVES IN INFANT FORMULA FOR HEALTHY DEVELOPMENT
    Publication number: 20230201233
    Abstract: Infant formula compositions and methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.
    Type: Application
    Filed: November 30, 2022
    Publication date: June 29, 2023
    Applicant: ChromaDex Inc.
    Inventors: Ryan Dellinger, Troy Rhonemus, Mark Morris, Dietrich Conze, Amy Boileau
  • Methods of synthesizing nicotinamide riboside
    Patent number: 11629163
    Abstract: Provided herein are efficient and scalable methods for the synthesis of nicotinamide riboside from riboside triacetate. Also provided are compositions comprising nicotinamide riboside, and therapeutic methods employing nicotinamide riboside.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: April 18, 2023
    Assignee: Elysium Health, Inc.
    Inventors: Eric Marcotulli, Dan Alminana, Ryan Dellinger, Mark Morris, Rajesh Thamatam
  • CRYSTALLINE FORMS OF NICOTINAMIDE RIBOSIDE CHLORIDE
    Publication number: 20230063175
    Abstract: Provided herein are crystalline forms of nicotinamide riboside chloride and methods of making the same. Also provided are compositions comprising the crystalline form of nicotinamide riboside chloride, and therapeutic methods employing the crystalline form of nicotinamide riboside chloride.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 2, 2023
    Inventors: Eric Marcotulli, Dan Alminana, Ryan Dellinger, Mark Morris
  • Use of nicotinamide riboside, nicotinic acid riboside, and nicotinamide mononucleotide, reduced nicotinyl compounds, and nicotinoyl compound derivatives in infant formula for healthy development
    Patent number: 11524022
    Abstract: Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: December 13, 2022
    Assignee: ChromaDex Inc.
    Inventors: Ryan Dellinger, Troy Rhonemus, Mark Morris, Dietrich Conze, Amy Boileau
  • NICOTINAMIDE RIBOSIDE FOR USE IN TREATING OR PREVENTING LIVER DAMAGE
    Publication number: 20220305040
    Abstract: Provided herein are methods and compositions related to treating and/or preventing liver related diseases and disorders and for improving liver health in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Application
    Filed: June 16, 2022
    Publication date: September 29, 2022
    Inventors: Ryan Dellinger, Santiago Roel Santos, Eric A. Marcotulli, Daniel A. Alminana, Mark Morris, Leonard Pershing Guarente
  • TREATING AND PREVENTING MOTOR NEURON DISEASES USING NICOTINAMIDE RIBOSIDE
    Publication number: 20220305039
    Abstract: Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Application
    Filed: May 16, 2018
    Publication date: September 29, 2022
    Inventors: José Maria Estrela Ariguel, José Enrique De La Rubia Orti, Ryan Dellinger
  • Crystalline forms of nicotinamide riboside chloride
    Patent number: 11414407
    Abstract: Provided herein are crystalline forms of nicotinamide riboside chloride and methods of making the same. Also provided are compositions comprising the crystalline form of nicotinamide riboside chloride, and therapeutic methods employing the crystalline form of nicotinamide riboside chloride.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: August 16, 2022
    Assignee: Elysium Health, Inc.
    Inventors: Eric Marcotulli, Dan Alminana, Ryan Dellinger, Mark Morris
  • Nicotinamide riboside for use in treating or preventing liver damage
    Patent number: 11389468
    Abstract: Provided herein are methods and compositions related to treating and/or preventing liver related diseases and disorders and for improving liver health in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 19, 2022
    Assignee: Elysium Health, Inc.
    Inventors: Ryan Dellinger, Santiago Roel Santos, Eric Marcotulli, Daniel A. Alminana, Mark Morris, Leonard Pershing Guarente
  • Treating and preventing kidney damage
    Patent number: 11129843
    Abstract: Provided herein are methods and compositions related to treating and/or preventing kidney related diseases and disorders, treating and/or preventing acute kidney injury, and for improving kidney health in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: September 28, 2021
    Assignee: Elysium Health, Inc.
    Inventors: Eric A. Marcotulli, Daniel A. Alminana, Leonard Pershing Guarente, Ryan Dellinger, Mark Morris
  • USE OF NICOTINAMIDE RIBOSIDE, NICOTINIC ACID RIBOSIDE, AND NICOTINAMIDE MONONUCLEOTIDE, REDUCED NICOTINYL COMPOUNDS, AND NICOTINOYL COMPOUND DERIVATIVES IN INFANT FORMULA FOR HEALTHY DEVELOPMENT
    Publication number: 20210228604
    Abstract: Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.
    Type: Application
    Filed: December 8, 2020
    Publication date: July 29, 2021
    Applicant: ChromaDex Inc.
    Inventors: Ryan Dellinger, Troy Rhonemus, Mark Morris, Dietrich Conze, Amy Boileau
  • NICOTINAMIDE RIBOSIDE FOR USE IN TREATING OR PREVENTING LIVER DAMAGE
    Publication number: 20210205342
    Abstract: Provided herein are methods and compositions related to treating and/or preventing liver related diseases and disorders and for improving liver health in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Application
    Filed: March 16, 2018
    Publication date: July 8, 2021
    Inventors: Ryan Dellinger, Santiago Roel Santos, Eric Marcotulli, Dan Alminana, Mark Morris, Leonard Pershing Guarente
  • METHODS AND COMPOSITIONS FOR TREATING MULTIPLE SCLEROSIS
    Publication number: 20210186996
    Abstract: Provided herein are methods and compositions related to treating and/or preventing multiple sclerosis in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Application
    Filed: November 30, 2018
    Publication date: June 24, 2021
    Inventors: Eric Marcotulli, Dan Alminana, Mark Morris, Ryan Dellinger