Patents by Inventor Ryan Denton

Ryan Denton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrogen dioxide storage device
    Patent number: 12350434
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Grant
    Filed: August 24, 2023
    Date of Patent: July 8, 2025
    Assignee: VERO Biotech Inc.
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Edward E. A. Bromberg, Ryan Denton, Bryan J. Johnson, David Fine
  • METHOD AND APPARATUS FOR CALIBRATION OF GAS AND LIQUID CONCENTRATION SENSORS WITHOUT THE NEED FOR KNOWN CALIBRATION STANDARDS
    Publication number: 20240159722
    Abstract: A device and method for calibrating a NO delivery device using NO and NO2 measurements, without using a known standard.
    Type: Application
    Filed: July 17, 2023
    Publication date: May 16, 2024
    Inventors: David H. FINE, Edward BROMBERG, Thorsten SCHMIDT, Ryan DENTON
  • METHOD AND APPARATUS FOR AUTOMATIC CALIBRATION
    Publication number: 20240094175
    Abstract: A device and method for calibrating a delivery device includes providing a container A containing a nitrite, providing a container B containing an acid, releasing the contents of containers A and B, allowing the nitrite and acid to mix, waiting for a predetermined time, allowing air to combine with the mixture, and using NO and traces of NO2 to check and calibrate NO and NO2 sensors.
    Type: Application
    Filed: June 21, 2023
    Publication date: March 21, 2024
    Inventors: David H. FINE, Edward BROMBERG, Thorsten SCHMIDT, Ryan DENTON, Lucas G. GAMERO, Gregory VASQUEZ
  • NITROGEN DIOXIDE STORAGE DEVICE
    Publication number: 20240075240
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Application
    Filed: August 24, 2023
    Publication date: March 7, 2024
    Inventors: Barry N. GELLMAN, Eddie TAJUDEEN, Lucas GAMERO, Joshua HOPKINS, Edward E.A. BROMBERG, Ryan DENTON, Bryan J. JOHNSON, David FINE
  • START-UP PROTOCOLS FOR NITRIC OXIDE DELIVERY DEVICE
    Publication number: 20230414896
    Abstract: Start-up protocols for a device and method for administering NO is described.
    Type: Application
    Filed: May 1, 2023
    Publication date: December 28, 2023
    Inventors: David H. FINE, Edward BROMBERG, Ryan DENTON, Jason WHITE, Lucas G. GAMERO, Bryan JOHNSON, Gregory VASQUEZ, Doug SONOSKY
  • DELIVERY OF ULTRA PURE NITRIC OXIDE (NO)
    Publication number: 20230398323
    Abstract: A system for deliverying a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.
    Type: Application
    Filed: March 16, 2023
    Publication date: December 14, 2023
    Inventors: David H. FINE, Gregory VASQUEZ, Bryan JOHNSON, Ryan DENTON, Lucas G. GAMERO
  • Nitrogen dioxide storage device
    Patent number: 11779725
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: October 10, 2023
    Assignee: VERO BIOTECH INC.
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Edward E. A. Bromberg, Ryan Denton, Bryan J. Johnson, David Fine
  • Method and apparatus for automatic calibration
    Patent number: 11754538
    Abstract: A device and method for calibrating a delivery device includes providing a container A containing a nitrite, providing a container B containing an acid, releasing the contents of containers A and B, allowing the nitrite and acid to mix, waiting for a predetermined time, allowing air to combine with the mixture, and using NO and traces of NO2 to check and calibrate NO and NO2 sensors.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: September 12, 2023
    Assignee: VERO BIOTECH INC.
    Inventors: David H. Fine, Edward Bromberg, Thorsten Schmidt, Ryan Denton, Lucas G. Gamero, Gregory Vasquez
  • Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards
    Patent number: 11740213
    Abstract: A device and method for calibrating a NO delivery device using NO and NO2 measurements, without using a known standard.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: August 29, 2023
    Assignee: VERO Biotech Inc.
    Inventors: David H. Fine, Edward Bromberg, Thorsten Schmidt, Ryan Denton
  • Start-up protocols for nitric oxide delivery device
    Patent number: 11672938
    Abstract: Start-up protocols for a device and method for administering NO is described.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: June 13, 2023
    Assignee: VERO Biotech LLC
    Inventors: David H. Fine, Edward Bromberg, Ryan Denton, Jason White, Lucas G. Gamero, Bryan Johnson, Gregory Vasquez, Doug Sonosky
  • Delivery of ultra pure nitric oxide (NO)
    Patent number: 11607520
    Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir containing a nitrogen dioxide source. A heating element can be configured to heat the reservoir, causing nitrogen dioxide vapor to exit the reservoir through a restrictor into a conduit. The nitrogen dioxide vapor can mix with gas from a gas supply, which can then flow to a cartridge that includes a surface-activated material saturated with an aqueous solution of a reducing agent. The cartridge can convert the nitrogen dioxide into nitric oxide.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: March 21, 2023
    Assignee: VERO Biotech Inc.
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
  • Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards
    Patent number: 11243197
    Abstract: A device and method for calibrating a NO delivery device using NO and NO2 measurements, without using a known standard.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: February 8, 2022
    Assignee: VERO Biotech LLC
    Inventors: David H. Fine, Edward Bromberg, Thorsten Schmidt, Ryan Denton
  • NITROGEN DIOXIDE STORAGE DEVICE
    Publication number: 20210121655
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Application
    Filed: August 7, 2020
    Publication date: April 29, 2021
    Applicant: VERO Biotech LLC
    Inventors: Barry N. GELLMAN, Eddie TAJUDEEN, Lucas GAMERO, Joshua HOPKINS, Edward E.A. BROMBERG, Ryan DENTON, Bryan J. JOHNSON, David FINE
  • Nitrogen dioxide storage device
    Patent number: 10737051
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4, activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 11, 2020
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Edward E. A. Bromberg, Ryan Denton, Bryan J. Johnson, David Fine
  • NITROGEN DIOXIDE STORAGE DEVICE
    Publication number: 20190255277
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4, activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 22, 2019
    Applicant: VERO BIOTECH LLC
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Edward E.A. Bromberg, Ryan Denton, Bryan J. Johnson, David Fine
  • DELIVERY OF ULTRA PURE NITRIC OXIDE (NO)
    Publication number: 20190217043
    Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.
    Type: Application
    Filed: January 14, 2019
    Publication date: July 18, 2019
    Applicant: VERO BIOTECH LLC
    Inventors: David H. FINE, Gregory VASQUEZ, Bryan Johnson, Ryan Denton, Lucas G. Gamero
  • Nitrogen dioxide storage cassette
    Patent number: 10213572
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4, activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: February 26, 2019
    Assignee: VERO BIOTECH LLC
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Edward E. A. Bromberg, Ryan Denton, Bryan J. Johnson, David Fine
  • Delivery of ultra pure nitric oxide (NO)
    Patent number: 10179222
    Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent. In certain embodiments, the reservoir includes a restrictor.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: January 15, 2019
    Assignee: VERO BIOTECH LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
  • NITROGEN DIOXIDE STORAGE CASSETTE
    Publication number: 20160106946
    Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4, activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
    Type: Application
    Filed: October 20, 2015
    Publication date: April 21, 2016
    Applicant: GENO LLC
    Inventors: Barry N. Gellman, Eddie Tajudeen, Lucas Gamero, Joshua Hopkins, Ed Bromberg, Ryan Denton, Brian J. Johnson, David Fine
  • DELIVERY OF ULTRA PURE NITRIC OXIDE (NO)
    Publication number: 20150374949
    Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.
    Type: Application
    Filed: November 18, 2014
    Publication date: December 31, 2015
    Applicant: GENO LLC
    Inventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero