Patents by Inventor Ryan Douglas Muir

Ryan Douglas Muir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200174142
    Abstract: The present disclosure provides a system and method for efficiently mining multi-threshold measurements acquired using photon counting pixel-array detectors for spectral imaging and diffraction analyses. Images of X-ray intensity as a function of X-ray energy were recorded on a 6 megapixel X-ray photon counting array detector through linear fitting of the measured counts recorded as a function of counting threshold. An analytical model is disclosed for describing the probability density of detected voltage, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Three-parameter fits to the model were independently performed for each pixel in the array for X-ray scattering images acquired for 13.5 keV and 15.0 keV X-ray energies. From the established pixel responses, multi-threshold composite images produced from the sum of 13.5 keV and 15.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 4, 2020
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, Nicholas Roman Pogranichniy
  • Patent number: 10416068
    Abstract: A quantitative optical microscopy arrangement is described. Specifically, a digital filter derived from linear discriminant analysis is described for recovering impulse responses in applications that may include photon counting from a high speed photodetector and applied to remove ringing distortions from impedance mismatch in multiphoton fluorescence microscopy. Training of the digital filter is achieved by defining temporally coincident and non-coincident transients and identifying the projection within filter-space that best separates the two classes. The training allows rapid data analysis by digital filtering. The LDA filter is also capable of recovering deconvolved impulses for single photon counting from highly distorted ringing waveforms from an impedance mismatched photomultiplier tube.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: September 17, 2019
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, Shane Zachary Sullivan
  • Patent number: 10409047
    Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: September 10, 2019
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Charles Addison Bouman, Ryan Douglas Muir, Shane Sullivan, Justin Allen Newman, Mark Carlsen, Suhas Sreehari
  • Patent number: 10162942
    Abstract: A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (LDR) for a single detector. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons, ions or particles present, the binomial distribution of observed counts for a given threshold, the mean number of photons, ions or particles can be determined well beyond the conventional limit.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: December 25, 2018
    Assignee: Purdue Research Foundation
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, David Joseph Kissick
  • Patent number: 10145968
    Abstract: The present disclosure provides a system and method for efficiently mining multi-threshold measurements acquired using photon counting pixel-array detectors for spectral imaging and diffraction analyses. Images of X-ray intensity as a function of X-ray energy were recorded on a 6 megapixel X-ray photon counting array detector through linear fitting of the measured counts recorded as a function of counting threshold. An analytical model is disclosed for describing the probability density of detected voltage, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Three-parameter fits to the model were independently performed for each pixel in the array for X-ray scattering images acquired for 13.5 keV and 15.0 keV X-ray energies. From the established pixel responses, multi-threshold composite images produced from the sum of 13.5 keV and 15.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 4, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, Nicholas Roman Pogranichniy
  • Publication number: 20180068090
    Abstract: A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (LDR) for a single detector. By explicitly considering the log-normal probability distribution in voltage transients as a function of the number of photons, ions or particles present, the binomial distribution of observed counts for a given threshold, the mean number of photons, ions or particles can be determined well beyond the conventional limit.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 8, 2018
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, David Joseph Kissick
  • Publication number: 20180045939
    Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 15, 2018
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Charles Addison Bouman, Ryan Douglas Muir, Shane Sullivan, Justin Allen Newman, Mark Carlsen, Suhas Sreehari
  • Patent number: 9784960
    Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: October 10, 2017
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Charles Addison Bouman, Ryan Douglas Muir, Shane Sullivan, Justin Allen Newman, Mark Carlsen, Suhas Sreehari
  • Publication number: 20160070093
    Abstract: A quantitative optical microscopy arrangement is described. Specifically, a digital filter derived from linear discriminant analysis is described for recovering impulse responses in applications that may include photon counting from a high speed photodetector and applied to remove ringing distortions from impedance mismatch in multiphoton fluorescence microscopy. Training of the digital filter is achieved by defining temporally coincident and non-coincident transients and identifying the projection within filter-space that best separates the two classes. The training allows rapid data analysis by digital filtering. The LDA filter is also capable of recovering deconvolved impulses for single photon counting from highly distorted ringing waveforms from an impedance mismatched photomultiplier tube.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 10, 2016
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, Shane Zachary Sullivan
  • Publication number: 20160004060
    Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
    Type: Application
    Filed: June 10, 2015
    Publication date: January 7, 2016
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Charles Addison Bouman, Ryan Douglas Muir, Shane Sullivan, Justin Allen Newman, Mark Carlsen
  • Publication number: 20150323687
    Abstract: The present disclosure provides a system and method for efficiently mining multi-threshold measurements acquired using photon counting pixel-array detectors for spectral imaging and diffraction analyses. Images of X-ray intensity as a function of X-ray energy were recorded on a 6 megapixel X-ray photon counting array detector through linear fitting of the measured counts recorded as a function of counting threshold. An analytical model is disclosed for describing the probability density of detected voltage, utilizing fractional photon counting to account for edge/corner effects from voltage plumes that spread across multiple pixels. Three-parameter fits to the model were independently performed for each pixel in the array for X-ray scattering images acquired for 13.5 keV and 15.0 keV X-ray energies. From the established pixel responses, multi-threshold composite images produced from the sum of 13.5 keV and 15.
    Type: Application
    Filed: May 11, 2015
    Publication date: November 12, 2015
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Ryan Douglas Muir, Nicholas Roman Pogranichniy