Abstract: A method of genetic testing utilizing a system of servers, databases, computers, software applications, or any other computing module. The computing modules allow for creation of a genetic test script and the analysis of genetic information based on the genetic test script. The system can also account for the use of proprietary biomarkers.

Abstract: This disclosure relates to methods and systems for a curated genetic variant database and systems and methods for submitting new genetic tests based on the information in the curated database. The methods and systems of the invention further provide for a single curated variant database that allows curation of genetic variants while protecting the proprietary nature of the information submitted to the database. The system and methods also provide for submission of new genetic tests based on genetic variants, conducting genetic tests, and for determining payments to submitters and test developers based on the genetic tests.

Abstract: A method of genetic testing utilizing a system of servers, databases, computers, software applications, or any other computing module. The computing modules allow for creation of a genetic test script and the analysis of genetic information based on the genetic test script. The system can also account for the use of proprietary biomarkers.

Abstract: A method of genetic testing utilizing a system of servers, databases, computers, software applications, or any other computing module. The computing modules allow for creation of a genetic test script and the analysis of genetic information based on the genetic test script. The system can also account for the use of proprietary biomarkers.

Abstract: Disclosed are systems and methods for managing and using a curated genetic biomarker database. The systems and methods allow for submission and curation of genetic biomarkers, the development of new genetic tests based on the submitted biomarkers, conducting the genetic tests, and accounting for payments due to biomarker submitters and test developers for use of the genetic tests.

Abstract: Disclosed are systems and methods for creating an in silico biomarker test. The systems and methods allow for receiving genetic or other biomarker information, along with patient metadata, and utilizing this information in order to create the new tests. The systems and methods may additionally include the ability to create genetic tests from raw genetic data received by the system. The systems and methods may utilize machine learning processes to determine the effect of one or more biomarkers on a phenotypic result for a patient based on one or more features determined to effect phenotypic results.

Abstract: A method of genetic testing utilizing a system of servers, databases, computers, software applications, or any other computing module. The computing modules allow for creation of a genetic test script and the analysis of genetic information based on the genetic test script. The system can also account for the use of proprietary biomarkers.

Abstract: Disclosed are systems and methods for facilitating licensing of intellectual property rights and transfer of payments between intellectual property rights holders and users or licensees while shielding patient privacy. Information contained in a patient records database is restricted such that one or more fields of information are not available to one or more users of a privacy facilitating system. The patient records database containing patient records including patient identification information and diagnostic information is accessed along with a proprietary records database containing records of proprietary biomarkers and intellectual property rights holders of the proprietary biomarkers. The patient records database and the proprietary records database are queried to determine the presence of a proprietary biomarker in a patient record.

Abstract: A system of collocated servers, databases, computers, software applications, or any other computing module for the processing and utilization of genetic information. The computing modules allow for the analysis of genetic information stored in a database and the reporting of genetic test results without the need for sending the genetic information across the internet.

Abstract: Rupture path logic methods of detecting, locating and isolating ruptures within a fluid piping system are disclosed, wherein a rupture within a piping system can be detected and isolated based solely upon local pressure and flow rate measurements at individual valves within the system without the need for communication of measured fluid data between valves at various locations throughout the system. A fluid characteristic is determined individually for each valve based upon the pressure and flow rate measurements at the valve, and that fluid characteristic is compared with set point fluid characteristic information to determine whether each valve is on a fluid path between a fluid supply source and a rupture.