Patents by Inventor Ryan E. Looper

Ryan E. Looper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial Compounds and Methods
    Publication number: 20230278987
    Abstract: The application is directed to compounds that are active as antibacterial agents. The compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes for making the compounds.
    Type: Application
    Filed: November 12, 2020
    Publication date: September 7, 2023
    Inventors: Paul R. Sebahar, Ryan E. LOOPER, Charles A. TESTA, Benlsaac C. TRESCO, Travis J. HAUSSENER, Hariprasada R. Kanna REDDY, Seth GRANT
  • Antimicrobial Compounds and Methods
    Publication number: 20230159491
    Abstract: The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 25, 2023
    Inventors: Ryan E. Looper, Paul Sebahar, Hariprasada R. Kanna Reddy, Travis J. Haussener, Charles A. Testa, Benlsaac C. Tresco, Seth Grant, Carmela Napolitano, Fabio Maria Sabbatini
  • Antimicrobial Compounds and Methods
    Publication number: 20230072397
    Abstract: The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 9, 2023
    Inventors: Ryan E. Looper, Paul Sebahar, Hariprasada R. Kanna Reddy, Travis J. Haussener, Charles A. Testa, Benlsaac C. Tresco, Seth Grant, Carmela Napolitano, Fabio Maria Sabbatini
  • COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES
    Publication number: 20220274949
    Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
    Type: Application
    Filed: May 10, 2022
    Publication date: September 1, 2022
    Applicants: Curza Global, LLC, University of Utah Research Foundation
    Inventors: Ryan E. Looper, Justin M. Salvant, Emily K. Kirkeby, Wenxing Guo, Katrin P. Guillen, Bryan E. Welm
  • Compositions and methods comprising a triaryl polyamine
    Patent number: 11352315
    Abstract: Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, or reduce biofilms, or to inhibit or substantially prevent biofilm formation. In some aspects, the present invention relates to polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms. In some aspects, the present invention relates to compositions and methods comprising the polyamine compound. In some aspects, the compounds, compositions, and methods enhance wound healing.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: June 7, 2022
    Assignees: Curza Global, LLC, University of Utah Research Foundation
    Inventors: Ryan E. Looper, Dustin Williams, Paul R. Sebahar, Travis J. Haussener, Hariprasada R. Kanna Reddy
  • Compositions and methods comprising substituted 2-aminoimidazoles
    Patent number: 11339140
    Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: May 24, 2022
    Assignees: Curza Global, LLC, The University of Utah
    Inventors: Ryan E. Looper, Justin M. Salvant, Emily K. Kirkeby, Wenxing Guo, Katrin P. Guillen, Bryan E. Welm
  • COMPOSITIONS AND METHODS COMPRISING A TRIARYL POLYAMINE
    Publication number: 20200031757
    Abstract: Compounds, compositions, and methods comprising a polyamine compound are described, which may be used to kill, disperse, treat, or reduce biofilms, or to inhibit or substantially prevent biofilm formation. In some aspects, the present invention relates to polyamine compounds that have antimicrobial or dispersing activity against a variety of bacterial strains capable of forming biofilms. In some aspects, the present invention relates to compositions and methods comprising the polyamine compound. In some aspects, the compounds, compositions, and methods enhance wound healing.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Applicants: Curza Global, LLC, University of Utah Research Foundation
    Inventors: Ryan E. Looper, Dustin Williams, Paul R. Sebahar, Travis J. Haussener, Hariprasada R. Kanna Reddy
  • COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES
    Publication number: 20200024251
    Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 23, 2020
    Applicants: Curza Global, LLC, University of Utah Research Foundation
    Inventors: Ryan E. Looper, Justin M. Salvant, Emily K. Kirkeby, Wenxing Guo, Katrin P. Guillen, Bryan E. Welm
  • Compositions and methods comprising 2-(acylamino)imidazoles
    Patent number: 10493061
    Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 3, 2019
    Assignees: Curza Global, LLC, University of Utag Research Foundation
    Inventors: Ryan E. Looper, Rachel M. Vaden, Joseph B. Gibbons, Justin M. Salvant, Anne V. Edwards, Matthew S. Sigman, Bryan E. Welm
  • METHOD OF PRODUCING N-ALKYL POLYAMINES
    Publication number: 20170298002
    Abstract: In one embodiment, the invention presents a process for the preparation of N-alkyl polyamines that includes (i) the conversion of an amino alcohol to an aminoalkyl alkylating agent with a halo or aldehyde reactive group and (ii) the addition of amines to an amine-containing alkylating agent to make an N-alkyl polyamine.
    Type: Application
    Filed: February 24, 2017
    Publication date: October 19, 2017
    Inventors: Ryan E. Looper, Paul R. Sebahar, Travis Haussener
  • COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES
    Publication number: 20170100375
    Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
    Type: Application
    Filed: September 16, 2016
    Publication date: April 13, 2017
    Inventors: Ryan E. Looper, Rachel M. Vaden, Joseph B. Gibbons, Justin M. Salvant, Anne V. Edwards, Matthew S. Sigman, Bryan E. Welm