Abstract: A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The constructed microscope with fiber spectroscopic probe is suitable for micro-sampling, Raman analysis, as well as fluorescence analysis and can be easily reconfigured for different excitation/detection wavelengths. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope.

Abstract: The present invention provides synchronization and control between the wavelength of a multi-wavelength illuminator and the image frames acquired by a video camera. In accordance with the present invention, the trailing edge of a camera expose-signal triggers a pre-loaded digital value to be output from a FIFO buffer. The digital value selects a particular illumination wavelength either directly or through a voltage from a digital to analog converter. The FIFO may be periodically refilled, or it may be a circular register.

Abstract: The present invention provides a control interface for one or more instruments that comprise an image acquisition system, the control interface consisting of kinesthetic controls that do not require visual attention. The control interface of the present invention maps kinesthetic controls such as sliders and knobs to a system computer and software running thereon which is directing the operation of individual imaging instruments.