Abstract: A single denture model that includes both tooth and soft tissue portions (e.g., gums and palate) may be provided in a computer-aided design (CAD) or computer-aided manufacturing (CAM) modeling environment. By cutting back soft tissue surfaces of the virtual denture model within the modeling environment, cutback volumes are formed that provide space for the subsequent application of a soft tissue insert that mimics soft tissue. A denture base including these cutback volumes can be fabricated from the virtual denture model, e.g., by milling or three-dimensional printing, and soft tissue inserts (e.g., custom-fabricated or prefabricated inserts) can be assembled onto the denture base to form a complete denture.