Abstract: A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members. The first and second ring components may be slideable through the pair of securing members, thereby radially adjusting the ring between a first dimension configuration and a second dimension configuration. In some example applications, the ring is dimensioned to be implanted into any one of the heart valves, the aortic valve, mitral valve, pulmonary valve and tricuspid valve. The ring may in some embodiments be used as an annuloplasty ring. The annuloplasty ring may be used to reshape a valve annulus, in particular to restore the annulus' normal shape and/or size.

Abstract: A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

Abstract: An apparatus and methods for the delivery of biocompatible materials such as anchors. The apparatus comprises an elongated body having a proximal end and an opposing distal end, a supporting arm extending outwardly from the distal end of the body, and a plurality of arms each extending outwardly from the distal end of the body. The plurality of arms may each define an arm lumen therewithin dimensioned to receive the biocompatible material. The apparatus comprises means for selectively moving each one of the plurality of arms relative to the longitudinal axis of the supporting arm between an expanded configuration and a collapsed configuration, and means for selectively deploying the biocompatible materials from within one or more of the arm lumens into a tissue of a subject.

Abstract: A tissue anchor is disclosed. The tissue anchor comprises a base and first, second, third and fourth prongs being joined to the base at proximal ends thereof. In some embodiments, each of the first, second, third and fourth prongs extends radially outwardly from the proximal end along an arcuate path towards a distal end. The first, second, third and fourth prongs may be radially symmetrically such that the anchor has radial symmetry about a central axis of the anchor.

Abstract: A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

Abstract: A tissue anchor such as an annular anchor is disclosed. The annular anchor comprises a base, a first prong, a second prong, and an alignment pin. The first and second prongs each comprises a proximal end joined to the base, extending outwardly to a respective distal end. The alignment pin is oriented to protrude radially outwardly from a wall of the base in a direction generally orthogonal to a central axis of the base. The alignment pin has a protruded end projecting through a first opening formed in the wall of the base. The alignment pin is adapted to slide within a groove of a delivery device when the annular anchor is loaded in the delivery device for deployment.

Abstract: A lock delivery system is disclosed. The lock mechanism is reversible between an unlocked configuration and a locked configuration. The lock mechanism may comprise a casing, and a first body and a second body arranged spaced-apart in the casing. The first body may comprise a first gripping portion extending to a first actuating arm, and a first spring arranged spaced-apart from the first actuating arm. The second body may comprise a second gripping portion extending to a second actuating arm, and a second spring arranged spaced-apart from the second actuating arm. The first and second bodies are each pivotable about a respective first pivot point and second pivot point so as to move the lock mechanism between an unlocked configuration and a locked configuration. A lock delivery catheter may be used as a means to move the lock mechanism between the unlocked configuration and the locked configuration.

Abstract: An apparatus and methods for the delivery of biocompatible materials such as anchors. The apparatus comprises an elongated body having a proximal end and an opposing distal end, a supporting arm extending outwardly from the distal end of the body, and a plurality of arms each extending outwardly from the distal end of the body. The plurality of arms may each define an arm lumen therewithin dimensioned to receive the biocompatible material. The apparatus comprises means for selectively moving each one of the plurality of arms relative to the longitudinal axis of the supporting arm between an expanded configuration and a collapsed configuration, and means for selectively deploying the biocompatible materials from within one or more of the arm lumens into a tissue of a subject.

Abstract: A lock delivery system is disclosed. The lock mechanism is reversible between an unlocked configuration and a locked configuration. The lock mechanism may comprise a casing, and a first body and a second body arranged spaced-apart in the casing. The first body may comprise a first gripping portion extending to a first actuating arm, and a first spring arranged spaced-apart from the first actuating arm. The second body may comprise a second gripping portion extending to a second actuating arm, and a second spring arranged spaced-apart from the second actuating arm. The first and second bodies are each pivotable about a respective first pivot point and second pivot point so as to move the lock mechanism between an unlocked configuration and a locked configuration. A lock delivery catheter may be used as a means to move the lock mechanism between the unlocked configuration and the locked configuration.

Abstract: Disclosed are corrosion inhibitor compounds and compositions useful in applications relating to the production, transportation, storage, and separation of crude oil and natural gas. Also disclosed are methods of using the compounds and compositions as corrosion inhibitors, particularly in applications relating to the production, transportation, storage, and separation of crude oil and natural gas.

Abstract: Disclosed are corrosion inhibitor compounds and compositions useful in applications relating to the production, transportation, storage, and separation of crude oil and natural gas. Also disclosed are methods of using the compounds and compositions as corrosion inhibitors, particularly in applications relating to the production, transportation, storage, and separation of crude oil and natural gas.