Abstract: Provided herein are methods and compositions for community-based screening of polymicrobial infections for the selection and administration of antibiotics and antibiotic combinations for treating infections associated with diseases such as cystic fibrosis, chronic obstructive pulmonary disease, and chronic sinus infections. The methods and compositions of this disclosure are advantageous in the sense that antibiotic effectiveness is assessed with respect to a community of microbes rather than a single microbial population, thus reflecting more accurately the in vivo disease environment and enabling the identification of beneficial antimicrobial therapeutics even when the primary bacterial strain shows antibiotic resistance.

Abstract: A ventilation device is supported in at a ventilation opening in a fabric panel of a building in which the fabric panel is supported under tension across a frame. The device includes a lower frame and an intermediate frame with respective flanges that receive a perimeter edge of the fabric panel about the ventilation opening therebetween. A cover is joined to the frames so as to prevent precipitation entering the frame opening while providing exterior ventilation from the ventilation opening of the building through one or more exterior openings in the cover.

Abstract: A ventilation device is supported in at a ventilation opening in a fabric panel of a building in which the fabric panel is supported under tension across a frame. The device includes a lower frame and an intermediate frame with respective flanges that receive a perimeter edge of the fabric panel about the ventilation opening therebetween. A cover is joined to the frames so as to prevent precipitation entering the frame opening while providing exterior ventilation from the ventilation opening of the building through one or more exterior openings in the cover.

Abstract: A wall system for forming a weather enclosure across a building opening in the frame of a building includes a flexible sheet of flexible material, a first rigid frame member secured across a first end of the flexible sheet, and a second rigid frame member secured across the flexible sheet in proximity to an opposing second end of the sheet. The first rigid frame remember is fixedly mounted on the building frame. A tensioning assembly is operatively connected between the second rigid frame member and the building frame so as to apply tension in the longitudinal direction to a portion of the flexible sheet. The tensioning between rigid frame members spanning across opposing ends of the sheet ensures that the sheet can be supported under significant tension throughout the sheet to enable the sheet to withstand considerable wind and precipitation loads.

Abstract: The head gasket for internal combustion engines may be used to seal cylinders between a cylinder block and a cylinder head. A head gasket may have multiple holes formed therein. An edge of a cylinder hole in the head gasket may have an annular groove formed therein. A ring may be disposed in the annular groove.

Abstract: The seal for the head gaskets of internal combustion engines may be a bead seal of material that may be elastic, resistant to compression and deformable under pressure. The bead seal may be attached around the holes in a malleable copper head gasket on each side of the head gasket. The bead seals on each side of a selected hole may be at different distances from the hole.