Patents by Inventor Ryan Iarrobino

Ryan Iarrobino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLASMA KALLIKREIN BINDING PROTEINS AND USES THEREOF IN TREATING HEREDITARY ANGIOEDEMA
    Publication number: 20260035482
    Abstract: Provided herein are plasma kallikrein binding proteins such as antibodies binding to active plasma kallikrein and methods of using such proteins in treating hereditary angioedema.
    Type: Application
    Filed: July 8, 2025
    Publication date: February 5, 2026
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Daniel J. Sexton, Burt Adelman, Yung Chyung, Christopher TenHoor, Jon A. Kenniston, Ryan Faucette, Ryan Iarrobino, Joseph Biedenkapp
  • Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema
    Patent number: 12384854
    Abstract: Provided herein are plasma kallikrein binding proteins such as antibodies binding to active plasma kallikrein and methods of using such proteins in treating hereditary angioedema.
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: August 12, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Daniel J. Sexton, Burt Adelman, Yung Chyung, Christopher TenHoor, Jon A. Kenniston, Ryan Faucette, Ryan Iarrobino, Joseph Biedenkapp
  • METHODS FOR THE TREATMENT OF MYASTHENIA GRAVIS
    Publication number: 20250066467
    Abstract: The present disclosure provides methods of treating myasthenia gravis comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of myasthenia gravis.
    Type: Application
    Filed: November 16, 2023
    Publication date: February 27, 2025
    Inventors: Sandeep KULKARNI, Yung CHYUNG, Susan Dana JONES, Ryan IARROBINO, W. Bradford MIDDLEKAUFF
  • METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE
    Publication number: 20250011416
    Abstract: The present disclosure provides methods of treating cardiovascular disease comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of cardiovascular disease.
    Type: Application
    Filed: September 18, 2024
    Publication date: January 9, 2025
    Inventors: Sandeep Kulkarni, Yung Chyung, Susan Dana Jones, Ryan Iarrobino, W. Bradford Middlekauff
  • METHODS FOR THE TREATMENT OF THYROID EYE DISEASE
    Publication number: 20250011417
    Abstract: The present disclosure provides methods of treating thyroid eye disease comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of thyroid eye disease.
    Type: Application
    Filed: September 18, 2024
    Publication date: January 9, 2025
    Inventors: Sandeep Kulkarni, Yung Chyung, Susan Dana Jones, Ryan Iarrobino, W. Bradford Middlekauff
  • USE OF ANTI-PRO/LATENT MYOSTATIN ANTIBODY FOR TREATING SPINAL MUSCULAR ATROPHY
    Publication number: 20240002490
    Abstract: The present disclosure relates to therapeutic methods, uses, and compositions comprising an anti-pro/latent myostatin antibody to treat spinal muscular atrophy (SMA) in human subjects, either as monotherapy or as an adjunct to a motor neuron-directed therapy, such as an SMN upregulator/corrector therapy.
    Type: Application
    Filed: October 25, 2021
    Publication date: January 4, 2024
    Inventors: George NOMIKOS, Guochen SONG, Ryan IARROBINO, Yung CHYUNG
  • Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema
    Patent number: 11084884
    Abstract: Provided herein are plasma kallikrein binding proteins such as antibodies binding to active plasma kallikrein and methods of using such proteins in treating hereditary angioedema.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: August 10, 2021
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Daniel J. Sexton, Burt Adelman, Yung Chyung, Christopher TenHoor, Jon A. Kenniston, Ryan Faucette, Ryan Iarrobino, Joseph Biedenkapp
  • PLASMA KALLIKREIN BINDING PROTEINS AND USES THEREOF IN TREATING HEREDITARY ANGIOEDEMA
    Publication number: 20210087293
    Abstract: Provided herein are plasma kallikrein binding proteins such as antibodies binding to active plasma kallikrein and methods of using such proteins in treating hereditary angioedema.
    Type: Application
    Filed: September 2, 2020
    Publication date: March 25, 2021
    Applicant: Dyax Corp.
    Inventors: Daniel J. Sexton, Burt Adelman, Yung Chyung, Christopher TenHoor, Jon A. Kenniston, Ryan Faucette, Ryan Iarrobino, Joseph Biedenkapp