Abstract: Provided herein are polypeptides that bind to a transferrin receptor, methods of generating such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.

Abstract: The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of Aß plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human.

Abstract: Provided herein are polypeptides that bind to a transferrin receptor, methods of generating such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.

Abstract: A dual-purpose agricultural cart for transporting and conditioning grain or other particulate material. The cart features a transportable frame, a holding container for receiving and holding the particulate material, a fan, and one or more airflow channels each having an inlet fed by the fan and at least one outlet positioned to open into the holding container at an elevation at or proximate a lower end of the holding container. The particulate material is aerated via upward fan-driven airflow from the outlet(s) of the one or more airflow channels. The same cart used to transport grain between a combine harvester and road transport vehicle during harvest can be used after harvest, or during harvest delays, the dry harvested grain before long term storage or long-distance transport.

Abstract: A dual-purpose agricultural cart for transporting and conditioning grain or other particulate material. The cart features a transportable frame, a holding container for receiving and holding the particulate material, a fan, and one or more airflow channels each having an inlet fed by the fan and at least one outlet positioned to open into the holding container at an elevation at or proximate a lower end of the holding container. The particulate material is aerated via upward fan-driven airflow from the outlet(s) of the one or more airflow channels. The same cart used to transport grain between a combine harvester and road transport vehicle during harvest can be used after harvest, or during harvest delays, the dry harvested grain before long term storage or long-distance transport.