Abstract: Devices and methods are disclosed for remote clinical monitoring performance of exercises using a smart resistance exercise device including a resistance band, a first handle connected to a first end of the resistance band and a second handle connected to a second end of the resistance band, a force sensing assembly operably coupled to the resistance band, and a local receiving device communicatively coupled to the force sensing assembly. The force sensing assembly of the device includes a housing, and a force sensor disposed in the housing and operatively connected to the resistance band to measure a force exerted on the resistance band. The force sensing assembly also includes a processing and communication module communicatively coupled to the force sensor to receive measurements of the force sensor and communicatively coupled to the local receiving device to transmit the measurements to the local receiving device.

Abstract: This invention provides a system and method that employs multiple measurements of various, relevant tissue states of a patient to detect and predict OH and similar conditions. These multi anatomic measurements are transformed by a multivariate algorithm to outputs that convey the diagnostic and prognostic risk of the disease of interest. This novel, multiple-measurement technique avoids use of a single measurement, which is generally unlikely to adequately extract sufficient information to drive a clinically useful test in the setting of complex system disease. The system and method herein thereby allows automated monitoring of currently stable patients who, are known or suspected to have OH and/or similar internal conditions on a substantially continuous basis.

Abstract: Devices and methods are disclosed for remote clinical monitoring performance of exercises using a smart resistance exercise device including a resistance band, a first handle connected to a first end of the resistance band and a second handle connected to a second end of the resistance band, a force sensing assembly operably coupled to the resistance band, and a local receiving device communicatively coupled to the force sensing assembly. The force sensing assembly of the device includes a housing, and a force sensor disposed in the housing and operatively connected to the resistance band to measure a force exerted on the resistance band. The force sensing assembly also includes a processing and communication module communicatively coupled to the force sensor to receive measurements of the force sensor and communicatively coupled to the local receiving device to transmit the measurements to the local receiving device.

Abstract: A support rig for a medical instrument can hold a medical instrument that is inserted into a patient in a fixed position and orientation relative to patient, so that the position and orientation of the medical instrument is not affected by the breathing or other motion of the patient. The support rig and medical instrument can be radiolucent and non-metallic, so that an image can be taken of the patient while the medical instrument is inserted in the patent and held by the support rig. The radiolucent support rig and medical instrument can allow for imaging, including x-ray, CT, and/or MRI, to occur simultaneously during the surgery. Surgical outcomes can be improved by using imaging to provide information about a tumor and/or anatomical structures during surgery.

Abstract: This invention provides a nasal guard, which can be constructed according to various manufacturing techniques (e.g. molding. 3D printing, etc.) for use during nasal sinus and skull base surgery to reduce aerosolized transmission to protect surgical staff, conserve the volatile supply of personal protective equipment (PPE) and reduce the introduction of particles into the operating room. The novel nasal guard, according to embodiments of this invention, can be readily applied to the patient's nose/nasal region during surgery and, while exposing the nostrils for access by surgical procedures, reduces aerosol emission from the nares. This allows for an adequate seal on a variety of face sizes/shapes without impeding access for surgical tools and/or does not otherwise interfere with surgical approach. The nasal guard herein is also compatible with standard suction equipment. The nasal guard is easy-to-use and ergonomic, and can be (is) constructed from biocompatible materials.

Abstract: Devices and methods are disclosed for remote clinical monitoring performance of exercises using a smart resistance exercise device including a resistance band, a first handle connected to a first end of the resistance band and a second handle connected to a second end of the resistance band, a force sensing assembly operably coupled to the resistance band, and a local receiving device communicatively coupled to the force sensing assembly. The force sensing assembly of the device includes a housing, and a force sensor disposed in the housing and operatively connected to the resistance band to measure a force exerted on the resistance band. The force sensing assembly also includes a processing and communication module communicatively coupled to the force sensor to receive measurements of the force sensor and communicatively coupled to the local receiving device to transmit the measurements to the local receiving device.

Abstract: A system and method for creating a cavity with a drill assembly provides a powered drill shaft assembly having an articulating tip and a position sensor along the drill shaft; a drill motor assembly with a rotational motor, linear actuator, torque sensor, rotation sensor, electrical resistance sensor and a controller unit having a plurality of programs providing user interface and controlling the operation of the powered drill arrangement; a shroud for the drill shaft with a water port; and a computer software package that combines user specifications with sensor data to control activation and displacement of the drill with a user interface, controls the motor for rotational speed and drilling depth, and gives sensor status, and a display displaying status of a drilling procedure and an image from an imaging device, and that is programmable for a set of parameters for a drilling procedure.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A support rig for a medical instrument can hold a medical instrument that is inserted into a patient in a fixed position and orientation relative to patient, so that the position and orientation of the medical instrument is not affected by the breathing or other motion of the patient. The support rig and medical instrument can non-metallic, so that an image can be taken of the patient while the medical instrument is inserted in the patent and held by the support rig.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A method for cardiovascular-dynamics correlated imaging includes receiving a time series of images of at least a portion of a patient, receiving a time series of cardiovascular data for the patient, evaluating correlation between the time series of images and the time series of cardiovascular data, and determining a property of the at least a portion of a patient, based upon the correlation. A system for cardiovascular-dynamics correlated imaging includes a processing device having: a processor, a memory communicatively coupled therewith, and a correlation module including machine-readable instructions stored in the memory that, when executed by the processor, perform the function of correlating a time series of images of at least a portion of a patient with a time series of cardiovascular data of the patient to determine a property of the at least a portion of a patient.

Abstract: A miniaturized cardiopulmonary bypass circuit for a mouse comprises at least one venous catheter connected to a patient, a dual channel peristaltic pump having one channel to move the blood by tubing from the patient, an oxygenator that removes gases from the blood and mixes the blood with fresh gases to oxygenate the blood, the blood being moved from the oxygenator to the arterial catheter by the dual channel peristaltic pump, and an arterial catheter. The blood is pumped by a two-channel roller pump into an inlet nozzle, where the flow of blood is transformed from tubular flow to planar flow. Gas exchange occurs inside the case while the blood flows down the central component. Blood then flows down the central component into the arterial reservoir. The arterial reservoir is connected to the second channel of the pump, and returned to the patient through a cannula.

Abstract: A system, method and device for monitoring the condition of an internal organ, such as a brain, by providing an internal electrode. The internal electrode is operatively connected to at least one surface, external, electrode, and a system handler. A signal is generated between the electrodes such that the electrical properties, including conductivity and impedance among others, can be measured at and across the electrodes. The electrode arrangement allows for continuous monitoring of an internal organ and, where desired, mapping of the electrical properties thereof. The system obtains pressure readings, nodal conductivity and/or electrode impedance to monitor, map and report the condition of the internal organ. A correlation procedure is provided for generating a graphical representation of the condition of an internal organ from the gathered data.

Abstract: A system, method and device for monitoring the condition of an internal organ, such as a brain, by providing an internal electrode. The internal electrode is operatively connected to at least one surface, external, electrode, and a system handler. A signal is generated between the electrodes such that the electrical properties, including conductivity and impedance among others, can be measured at and across the electrodes. The electrode arrangement allows for continuous monitoring of an internal organ and, where desired, mapping of the electrical properties thereof. The system obtains pressure readings, nodal conductivity and/or electrode impedance to monitor, map and report the condition of the internal organ. A correlation procedure is provided for generating a graphical representation of the condition of an internal organ from the gathered data.