Patents by Inventor Ryan J. Watts

Ryan J. Watts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF AXON DEGENERATION
    Publication number: 20180325992
    Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
    Type: Application
    Filed: February 28, 2018
    Publication date: November 15, 2018
    Inventors: Ryan J. WATTS, Mark CHEN, Joseph Wesley LEWCOCK, Christine POZNIAK, Arundhati SENGUPTA-GHOSH
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180134797
    Abstract: The present invention relates to anti-trans-ferrin receptor antibodies and methods of their use.
    Type: Application
    Filed: November 18, 2015
    Publication date: May 17, 2018
    Applicant: Genentech, Inc.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S Dennis, James A Ernst, Ryan J Watts, Gregory A Lazar
  • Modulation of axon degeneration
    Patent number: 9937224
    Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: April 10, 2018
    Assignee: Genentech, Inc.
    Inventors: Ryan J. Watts, Mark Chen, Joseph Wesley Lewcock, Christine Pozniak, Arundhati Sengupta-Ghosh
  • ANTI-TRANSFERRIN RECEPTOR / ANTI-BACE1 MULTISPECIFIC ANTIBODIES AND METHODS OF USE
    Publication number: 20180057604
    Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 1, 2018
    Applicants: Genentech, Inc., Adimab LLC
    Inventors: Yichin Liu, Jasvinder Atwal, Cecilia Pui Chi Chiu, Ryan J. Watts, Yan WU, Eric Krauland, Michael Feldhaus, Yin Zhang, Joy Yu Zuchero, Jessica Couch, Mark S Dennis, James A Ernst, Gregory A Lazar
  • Nucleic acid molecules encoding for BACE1 antibodies
    Patent number: 9879094
    Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: January 30, 2018
    Assignee: Genentech, Inc.
    Inventors: Jasvinder Atwal, Yongmei Chen, Cecilia Pui Chi Chiu, Robert A. Lazarus, Weiru Wang, Ryan J. Watts, Yan Wu, Yingnan Zhang
  • BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180000964
    Abstract: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
    Type: Application
    Filed: June 9, 2017
    Publication date: January 4, 2018
    Applicant: Genentech, Inc.
    Inventors: Christine Tan, Ryan J. Watts, Joy Yu Zuchero, Xiaocheng Chen, Mark S. Dennis
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180002433
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Application
    Filed: June 5, 2017
    Publication date: January 4, 2018
    Applicant: Genentech, Inc.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • ANTIBODIES AGAINST BACE1 AND USE THEREOF FOR NEURAL DISEASE IMMUNOTHERAPY
    Publication number: 20170362339
    Abstract: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
    Type: Application
    Filed: November 18, 2015
    Publication date: December 21, 2017
    Applicants: Genentech, Inc., Adimab LLC
    Inventors: Yichin Liu, Jasvinder Atwal, Cecilia Pui Chi Chiu, Ryan J. Watts, Yan WU, Eric Krauland, Michael Feldhaus
  • Anti-transferrin receptor antibodies and methods of use
    Patent number: 9708406
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: July 18, 2017
    Assignee: GENENTECH, INC.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • METHODS AND COMPOSITIONS FOR NEURAL DISEASE IMMUNOTHERAPY
    Publication number: 20170058049
    Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
    Type: Application
    Filed: August 11, 2016
    Publication date: March 2, 2017
    Applicant: Genentech, Inc.
    Inventors: Jasvinder Atwal, Yongmei Chen, Cecilia Pui Chi Chiu, Robert A. Lazarus, Weiru Wang, Ryan J. Watts, Yan Wu, Yingnan Zhang
  • NEUROPILIN ANTAGONISTS
    Publication number: 20160304613
    Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Application
    Filed: February 6, 2015
    Publication date: October 20, 2016
    Inventors: Ryan J. WATTS, Yan WU
  • MODULATION OF AXON DEGENERATION
    Publication number: 20160279190
    Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
    Type: Application
    Filed: June 30, 2015
    Publication date: September 29, 2016
    Inventors: Ryan J. WATTS, Mark CHEN, Joseph Wesley LEWCOCK, Christine POZNIAK, Arundhati SENGUPTA-GHOSH
  • Methods and compositions for neural disease immunotherapy
    Patent number: 9453079
    Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: September 27, 2016
    Assignee: Genentech, Inc.
    Inventors: Jasvinder Atwal, Yongmei Chen, Cecilia Pui Chi Chiu, Robert A. Lazarus, Weiru Wang, Ryan J. Watts, Yan Wu, Yingnan Zhang
  • MODULATION OF AXON DEGENERATION
    Publication number: 20160161470
    Abstract: The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using modulators of particular target proteins to modulate degeneration of neurons or portions thereof, such as axons.
    Type: Application
    Filed: August 10, 2015
    Publication date: June 9, 2016
    Inventors: Ryan J. WATTS, Mark CHEN, Joseph Wesley LEWCOCK, Christine POZNIAK, Arundhati SENGUPTA-GHOSH
  • Methods for identifying safe and functional humanized antibodies
    Patent number: 9221900
    Abstract: The present invention is related to safe and functional antibodies for the therapeutic and diagnostic use in the treatment of an amyloidosis, a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: December 29, 2015
    Assignees: AC IMMUNE S.A., GENENTECH, INC.
    Inventors: Andrea Pfeifer, Andreas Muhs, Oskar Adolfsson, Ryan J. Watts
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20150110791
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Application
    Filed: May 20, 2014
    Publication date: April 23, 2015
    Applicant: GENENTECH, INC.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • Anti-neuropilin antibodies and methods of use
    Patent number: 8993249
    Abstract: The invention provides anti-NRP1 antibodies and methods of using the same.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: March 31, 2015
    Assignee: Genentech, Inc.
    Inventors: Maike Schmidt, Christopher Adam Callahan, Jo-Anne S. Hongo, Hartmut Koeppen, Ryan J. Watts
  • METHODS AND COMPOSITIONS FOR NEURAL DISEASE IMMUNOTHERAPY
    Publication number: 20140286963
    Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 25, 2014
    Applicant: GENENTECH, INC.
    Inventors: Jasvinder Atwal, Yongmei Chen, Cecilia Pui Chi Chiu, Robert A. Lazarus, Weiru Wang, Ryan J. Watts, Yan Wu, Yingnan Zhang
  • METHODS FOR DETECTING NEURODEGENERATIVE DISEASES OR DISORDERS
    Publication number: 20140255301
    Abstract: Methods of identifying, diagnosing, and prognosing a neurodegenerative disease, or disorder, are provided. Also provided are methods for determining whether a neuron is at risk or is undergoing neurodegeneration. The methods comprise determining whether at least one of the genes tbx6 and dleu2 is overexpressed.
    Type: Application
    Filed: November 28, 2011
    Publication date: September 11, 2014
    Inventors: Mark Chen, Ryan J. Watts
  • Neuropilin antagonists
    Patent number: 8795660
    Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: August 5, 2014
    Assignee: Genentech, Inc.
    Inventors: Ryan J. Watts, Yan Wu