Patents by Inventor RYAN JAMES GILBERT

RYAN JAMES GILBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VITRO CULTURE MODEL OF ANISOTROPIC TO ISOTROPIC TRANSITIONS
    Publication number: 20220243155
    Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
    Type: Application
    Filed: September 7, 2021
    Publication date: August 4, 2022
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Christopher John RIVET, Gregory Patrick DESMOND, Jonathan Michael ZUIDEMA, Ryan James GILBERT
  • Vitro culture model of anisotropic to isotropic transitions
    Patent number: 11149241
    Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: October 19, 2021
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Christopher John Rivet, Gregory Patrick Desmond, Jonathan Michael Zuidema, Ryan James Gilbert
  • THREE-DIMENSIONAL SCAFFOLDS, METHODS FOR FABRICATING THE SAME, AND METHODS OF TREATING A PERIPHERAL NERVE OR SPINAL CORD INJURY
    Publication number: 20190350688
    Abstract: One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction substantially perpendicular to a general direction of the fibers. Another aspect of the invention provides a method for fabricating a three-dimensional scaffold. The method includes: electro spinning a plurality of fibers to produce at least one layer of highly-aligned fibers and forming the at least one layer of highly-aligned fibers into a three-dimensional scaffold without disturbing the alignment of the highly-aligned polymer fibers. A further aspect of the invention provides methods for using a three-dimensional scaffold to treat nerve or spinal cord injury.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 21, 2019
    Inventors: Andres Hurtado, Ryan James Gilbert, Han Bing Wang, Jared M. Cregg, Michael E. Mullins, Martin Oudega
  • Nanocomposite scaffold for the in vitro isolation of cells
    Patent number: 10392594
    Abstract: The present invention is directed to devices, methods and kits for cell-specific sorting of cells from a mixed population, e.g., from a tumor sample. Aspects of the invention combine aligned, electrospun microfibers with drug- or protein-releasing nanospheres to isolate cancer cells from tumor biopsies.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: August 27, 2019
    Assignee: Renssealer Polytechnic Institute
    Inventors: Ryan James Gilbert, Elizabeth Hager Cothren, Gregory Patrick Desmond, Marc Andrew Burnette, Erica Victoria Hoey, Stephanie Christine Krom, Clarissa May Herman
  • VITRO CULTURE MODEL OF ANISOTROPIC TO ISOTROPIC TRANSITIONS
    Publication number: 20190185798
    Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 20, 2019
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Christopher John RIVET, Gregory Patrick Desmond, Jonathan Michael Zuidema, Ryan James Gilbert
  • In vitro culture model of anisotropic to isotropic transitions
    Patent number: 10253287
    Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: April 9, 2019
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Christopher John Rivet, Gregory Patrick Desmond, Jonathan Michael Zuidema, Ryan James Gilbert
  • Nanocomposite Scaffold for the In Vitro Isolation of Cells
    Publication number: 20170283759
    Abstract: The present invention is directed to devices, methods and kits for cell-specific sorting of cells from a mixed population, e.g., from a tumor sample. Aspects of the invention combine aligned, electrospun microfibers with drug-or protein-releasing nanospheres to isolate cancer cells from tumor biopsies.
    Type: Application
    Filed: September 28, 2015
    Publication date: October 5, 2017
    Inventors: Ryan James Gilbert, Elizabeth Hager Cothren, Gregory Patrick Desmond, Marc Andrew Burnette, Erica Victoria Hoey, Stephanie Christine Krom, Clarissa May Herman
  • IN VITRO CULTURE MODEL OF ANISOTROPIC TO ISOTROPIC TRANSITIONS
    Publication number: 20170253843
    Abstract: Cell culture devices, and related methods and kits, for modeling isotropic-to-anisotropic cellular transitions are provided. The devices can include a substrate having an isotropic film surface with one or more regions of aligned fibers dispersed thereon.
    Type: Application
    Filed: August 25, 2015
    Publication date: September 7, 2017
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: CHRISTOPHER JOHN RIVET, GREGORY PATRICK DESMOND, JONATHAN MICHAEL ZUIDEMA, RYAN JAMES GILBERT