Abstract: A digital twin model based operation and optimization of a reverse osmosis plant uses a data processing system to receive data for a reverse osmosis membrane in a plant that with a plurality of assets. The data processing system can determine a level of performance of the membrane based on the data for the membrane input into a model generated with sa topology indicative of one or more relationships and a flow path between the plurality of assets, predict, based on the model and responsive to the level of performance input into an optimization function for the plant, a time at which the level of performance degrades below a threshold, and provide an indication of the time at which the level of performance degrades below the threshold predicted using the optimization function to cause servicing of the membrane used to process the fluid at the plant.