Patents by Inventor Ryan John Hansen

Ryan John Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pegylated Insulin Lispro Compounds
    Publication number: 20150297681
    Abstract: The present invention relates to the field of diabetes. More particularly, the invention relates to PEGylated insulin lispro compounds that are PEGylated with high molecular weight poly(ethylene glycol), are highly soluble at physiological pH, have an extended duration of action, and characterized by pharmacokinetic, pharmacodynamic, and/or activity peak-trough ratios of less than 2. The invention also relates to methods of providing such molecules, to pharmaceutical compositions containing them, and to their therapeutic uses.
    Type: Application
    Filed: May 1, 2015
    Publication date: October 22, 2015
    Applicant: ELI LILLY AND COMPANY
    Inventors: John Michael Beals, Gordon Butler Cutler, JR., Ryan John Hansen, Shun Li, Lianshan Zhang, Brandon Doyle, Shahriar Shirani
  • PEGylated insulin lispro compounds
    Patent number: 9050371
    Abstract: The present invention relates to the field of diabetes. More particularly, the invention relates to PEGylated insulin lispro compounds that are PEGylated with high molecular weight poly(ethylene glycol), are highly soluble at physiological pH, have an extended duration of action, and characterized by pharmacokinetic, pharmacodynamic, and/or activity peak-trough ratios of less than 2. The invention also relates to methods of providing such molecules, to pharmaceutical compositions containing them, and to their therapeutic uses.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: June 9, 2015
    Assignee: Eli Lilly and Company
    Inventors: John Michael Beals, Gordon Butler Cutler, Jr., Ryan John Hansen, Shun Li, Lianshan Zhang
  • Pegylated Insulin Lispro Compounds
    Publication number: 20110105392
    Abstract: The present invention relates to the field of diabetes. More particularly, the invention relates to PEGylated insulin lispro compounds that are PEGylated with high molecular weight poly(ethylene glycol), are highly soluble at physiological pH, have an extended duration of action, and characterized by pharmacokinetic, pharmacodynamic, and/or activity peak-trough ratios of less than 2. The invention also relates to methods of providing such molecules, to pharmaceutical compositions containing them, and to their therapeutic uses.
    Type: Application
    Filed: June 9, 2009
    Publication date: May 5, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: John Michael Beals, Gordon Butler Cutler, JR., Brandon Lee Doyle, Ryan John Hansen, Shun Li, Shahriar Shirani, Lianshan Zhang
  • PEGYLATED ABETA FAB
    Publication number: 20100015155
    Abstract: A method to treat conditions associated with A? peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A? peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.
    Type: Application
    Filed: January 9, 2008
    Publication date: January 21, 2010
    Inventors: Kelly Renee Bales, Thomas Frank Bumol, Chi-Kin Chow, Ronald Bradley Demattos, Ryan John Hansen, Uma Kuchibhotla, Jirong Lu, Peter Colon McDonnell
  • PEGYLATED INSULIN LISPRO COMPOUNDS
    Publication number: 20090312236
    Abstract: The present invention relates to the field of diabetes. More particularly, the invention relates to PEGylated insulin lispro compounds that are PEGylated with high molecular weight poly(ethylene glycol), are highly soluble at physiological pH, have an extended duration of action, and characterized by pharmacokinetic, pharmacodynamic, and/or activity peak-trough ratios of less than 2. The invention also relates to methods of providing such molecules, to pharmaceutical compositions containing them, and to their therapeutic uses.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 17, 2009
    Inventors: John Michael Beals, Gordon Butler Cutler, JR., Brandon Doyle, Ryan John Hansen, Shun Li, Sean Shirani, Lianshan Zhang