Patents by Inventor Ryan Koehler

Ryan Koehler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Digital assays for mutation detection
    Patent number: 9347095
    Abstract: Provided herein are methods, compositions, and kits for detecting alleles using a single probe or a single primer set. Also, provided herein are methods, compositions, and kits for detecting allelic variants using a single probe or a single primer set. Also, provided herein are methods, compositions, and kits for determining a polymerization error rate.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 24, 2016
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: John Regan, Samantha Cooper, Austin So, Ryan Koehler, Luz Montesclaros
  • DIGITAL ASSAYS FOR MUTATION DETECTION
    Publication number: 20140309128
    Abstract: Provided herein are methods, compositions, and kits for detecting alleles using a single probe or a single primer set. Also, provided herein are methods, compositions, and kits for detecting allelic variants using a single probe or a single primer set. Also, provided herein are methods, compositions, and kits for determining a polymerization error rate.
    Type: Application
    Filed: March 13, 2014
    Publication date: October 16, 2014
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: John Regan, Samantha Cooper, Austin So, Ryan Koehler, Luz Montesclaros
  • Universal-tagged oligonucleotide primers and methods of use
    Publication number: 20070128654
    Abstract: The present invention relates to universal-tagged oligonucleotide primers, and to methods of using the primers for amplifying the genome.
    Type: Application
    Filed: January 18, 2007
    Publication date: June 7, 2007
    Inventors: Kai Lao, Caifu Chen, Ryan Koehler, Charles Scafe, Gary Schroth
  • Polynucleotide sequence detection assays and analysis
    Publication number: 20060141475
    Abstract: Methods and software for associating mobility probes with target macromolecules are discussed. By encoding the identities of macromolecules of interest with a universal set of tag portions complementary to a universal set of mobility probes, reactions varying in their input starting material may be identified using the same universal set of mobility probes. This allows the universal collection of mobility probes to be used in a target macromolecule-independent manner. Software is used to decode the associations between the mobility probes and a given target macromolecular identity.
    Type: Application
    Filed: November 19, 2003
    Publication date: June 29, 2006
    Applicant: Applera Corporation
    Inventors: Barnett Rosenblum, David Holden, Yuandan Lou, Ryan Koehler, Srinivasa Ramachandra
  • Modulators of insulin receptor activity
    Publication number: 20030078188
    Abstract: Methods to identify compounds which have at least one characteristic selected from the group consisting of a composition that
    Type: Application
    Filed: October 25, 2001
    Publication date: April 24, 2003
    Inventors: Lawrence M. Kauvar, Richard Sportsman, Hugo O. Villar, Wayne R. Spevak, Ron A. Kohanski, Apparao Satyam, Ryan Koehler