Patents by Inventor Ryan L. Truby

Ryan L. Truby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200360567
    Abstract: A 3D printed tubular construct, such as a nephron, with or without embedded vasculature as well as methods of printing tubular tissue constructs are described.
    Type: Application
    Filed: May 29, 2020
    Publication date: November 19, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, Kimberly A. Homan, David B. Kolesky, Ryan L. Truby, Mark A. Skylar-Scott
  • Patent number: 10702630
    Abstract: A 3D printed tubular construct, such as a nephron, with or without embedded vasculature as well as methods of printing tubular tissue constructs are described.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: July 7, 2020
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Jennifer A. Lewis, Kimberly A. Homan, David B. Kolesky, Ryan L. Truby, Mark A. Skylar-Scott
  • Patent number: 10612986
    Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 7, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, Joseph T. Muth, Daniel M. Vogt, Ryan L. Truby, Yigit Menguc, David B. Kolesky, Robert J. Wood
  • Publication number: 20190094089
    Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.
    Type: Application
    Filed: October 11, 2018
    Publication date: March 28, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, Joseph T. Muth, Daniel M. Vogt, Ryan L. Truby, Yigit Menguc, David B. Kolesky, Robert J. Wood
  • Publication number: 20190022283
    Abstract: A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition.
    Type: Application
    Filed: September 26, 2018
    Publication date: January 24, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. LEWIS, David B. KOLESKY, Mark A. SKYLAR-SCOTT, Kimberly A. HOMAN, Ryan L. TRUBY, Amelia Sydney GLADMAN
  • Patent number: 10151649
    Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: December 11, 2018
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Jennifer A. Lewis, Joseph T. Muth, Daniel M. Vogt, Ryan L. Truby, Yigit Menguc, David B. Kolesky, Robert J. Wood
  • Patent number: 10117968
    Abstract: A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: November 6, 2018
    Assignee: President And Fellows Of Harvard College
    Inventors: Jennifer A. Lewis, David B. Kolesky, Mark A. Skylar-Scott, Kimberly A. Homan, Ryan L. Truby, Amelia Sydney Gladman
  • Publication number: 20180110901
    Abstract: A 3D printed tubular construct, such as a nephron, with or without embedded vasculature as well as methods of printing tubular tissue constructs are described.
    Type: Application
    Filed: May 4, 2016
    Publication date: April 26, 2018
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, Kimberly A. Homan, David B. Kolesky, Ryan L. Truby, Mark A. Skylar-Scott
  • Publication number: 20160287756
    Abstract: A printed tissue construct comprises one or more tissue patterns, where each tissue pattern comprises a plurality of viable cells of one or more predetermined cell types. A network of vascular channels interpenetrates the one or more tissue patterns. An extracellular matrix composition at least partially surrounds the one or more tissue patterns and the network of vascular channels. A method of printing a tissue construct with embedded vasculature comprises depositing one or more cell-laden filaments, each comprising a plurality of viable cells, on a substrate to form one or more tissue patterns. Each of the one or more tissue patterns comprises one or more predetermined cell types. One or more sacrificial filaments, each comprising a fugitive ink, are deposited on the substrate to form a vascular pattern interpenetrating the one or more tissue patterns. The vascular pattern and the one or more tissue patterns are at least partially surrounded with an extracellular matrix composition.
    Type: Application
    Filed: November 4, 2014
    Publication date: October 6, 2016
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, David B. Kolesky, Mark A. Skylar-Scott, Kimberly A. Homan, Ryan L. Truby, Amelia Sydney Gladman
  • Publication number: 20160290880
    Abstract: A printed stretchable strain sensor comprises a seamless elastomeric body and a strain-sensitive conductive structure embedded in the seamless elastomeric body. The strain-sensitive conductive structure comprises one or more conductive filaments arranged in a continuous pattern. A method of printing a stretchable strain sensor comprises depositing one or more conductive filaments in a predetermined continuous pattern into or onto a support matrix. After the depositing, the support matrix is cured to embed a strain-sensitive conductive structure in a seamless elastomeric body.
    Type: Application
    Filed: November 17, 2014
    Publication date: October 6, 2016
    Applicant: President and Fellows of Harvard College
    Inventors: Jennifer A. Lewis, Joseph T. Muth, Daniel M. Vogt, Ryan L. Truby, Yigit Menguc, David B. Kolesky, Robert J. Wood