Patents by Inventor Ryan Landis

Ryan Landis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230357166
    Abstract: The present invention provides, in part, piperazine-based lipid compounds of Formula (I), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
    Type: Application
    Filed: September 23, 2021
    Publication date: November 9, 2023
    Inventors: Saswata KARMAKAR, Ramesh DASARI, Ryan LANDIS
  • Publication number: 20230071228
    Abstract: The present invention provides, in part, cyclic amino acid lipid compounds of formula (A?), and sub-formulas thereof or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
    Type: Application
    Filed: November 7, 2019
    Publication date: March 9, 2023
    Inventors: Yi Zhang, Frank DeRosa, Shrirang Karve, Michael Heartlein, Saswata Karmakar, Ryan Landis
  • Patent number: 10858398
    Abstract: The presently disclosed subject matter is directed to an assay that detects and quantitatively determines the activity of a lytic peptide that exhibits antimicrobial activity, such as LL-37. Particularly, the assay comprises inducing and/or transfecting bacteria to produce high levels of an enzyme, such as ?-galactosidase. The bacteria are then preserved by lyophilization. After a desired amount of time, the bacteria are hydrated with a target sample from a subject suspected of having a specific disease or disorder characterized by an increase in levels of lytic peptide. In the presence of lytic peptide, the enzyme is released from the interior of the bacteria, which can then be detected by alteration of the enzyme substrate. In the absence of lytic peptide, the enzyme remains within the bacteria and no detection of the enzyme occurs.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: December 8, 2020
    Assignee: Deetex, LLC
    Inventors: James Hartmann, Ryan Landis, Michelle Ryan, Yousseff Mottii
  • Publication number: 20190300930
    Abstract: The presently disclosed subject matter is directed to an assay that detects and quantitatively determines the activity of a lytic peptide that exhibits antimicrobial activity, such as LL-37. Particularly, the assay comprises inducing and/or transfecting bacteria to produce high levels of an enzyme, such as ?-galactosidase. The bacteria are then preserved by lyophilization. After a desired amount of time, the bacteria are hydrated with a target sample from a subject suspected of having a specific disease or disorder characterized by an increase in levels of lytic peptide. In the presence of lytic peptide, the enzyme is released from the interior of the bacteria, which can then be detected by alteration of the enzyme substrate. In the absence of lytic peptide, the enzyme remains within the bacteria and no detection of the enzyme occurs.
    Type: Application
    Filed: April 2, 2019
    Publication date: October 3, 2019
    Applicant: Deetex, LLC
    Inventors: James Hartmann, Ryan Landis, Michelle Ryan, Yousseff Mottii
  • Publication number: 20190300575
    Abstract: The presently disclosed subject matter is directed to an assay that detects and quantitatively determines the activity of a lytic peptide that exhibits antimicrobial activity, such as LL-37. Particularly, the assay comprises inducing and/or transfecting bacteria to produce high levels of an enzyme, such as ?-galactosidase. The bacteria are then preserved by lyophilization. After a desired amount of time, the bacteria are hydrated with a target sample from a subject suspected of having a specific disease or disorder characterized by an increase in levels of lytic peptide. In the presence of lytic peptide, the enzyme is released from the interior of the bacteria, which can then be detected by alteration of the enzyme substrate. In the absence of lytic peptide, the enzyme remains within the bacteria and no detection of the enzyme occurs.
    Type: Application
    Filed: March 28, 2019
    Publication date: October 3, 2019
    Applicant: Deetex, LLC
    Inventors: James Hartmann, Ryan Landis, Michelle Ryan, Yousseff Mottii
  • Patent number: 7237702
    Abstract: A garment hanger that folds around a point or series of points near the hook of the hanger, and is adapted to automatically extend to its original unfolded position upon release is disclosed. More specifically, an improved hanger, also referred to as a suspension device, with a hook, having a first member and a second member, with a pivot near the hook, adapted to allow movement of the first member and the second member between a first position and a second position is disclosed.
    Type: Grant
    Filed: April 22, 2004
    Date of Patent: July 3, 2007
    Inventors: Gary Landis, Cheryl Landis, Ryan Landis
  • Publication number: 20040211797
    Abstract: A garment hanger that folds around a point or series of points near the hook of the hanger, and is adapted to automatically extend to its original unfolded position upon release is disclosed. More specifically, an improved hanger, also referred to as a suspension device, with a hook, having a first member and a second member, with a pivot near the hook, adapted to allow movement of the first member and the second member between a first position and a second position is disclosed.
    Type: Application
    Filed: April 22, 2004
    Publication date: October 28, 2004
    Inventors: Gary Landis, Cheryi Landis, Ryan Landis