Patents by Inventor Ryan M. Lee

Ryan M. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12590313
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: March 31, 2026
    Assignee: CORTEVA AGRISCIENCE LLC
    Inventors: Sandeep Kumar, Ryan M. Lee, Stephen Novak, Andrew F. Worden
  • Publication number: 20260078153
    Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.
    Type: Application
    Filed: August 6, 2025
    Publication date: March 19, 2026
    Applicant: CORTEVA AGRISCIENCE LLC
    Inventors: JOEL J. SHEETS, JANNA MAI ARMSTRONG, TRISTAN E. CORAM, AUDREY JANE ETTER, TODD P. GLANCY, TIMOTHY D. HEY, JAMES E. KING, RYAN M. LEE, JIANQUAN LI, GAOFENG LIN, KRISHNA M. MADDURI, THOMAS MEADE, KENNETH NARVA, SEK YEE TAN
  • Patent number: 12414679
    Abstract: A rigid hollow tubular adapter releasably attached at a longitudinal nozzle end to a flexible tube during equine nasogastric intubation comprising an annular sleeve having a stationary tubular member and a slidable tubular member. The slidable tubular member is delimited at its ends by the stationary tubular member and a detent member disposed between an equine reflux drainage hole and a longitudinal mouthpiece end. Operator's puffs of airflow through a mouthpiece urges the slidable member to slide toward the detent member closing the equine drainage hole to enable passage of medication into the equine stomach. Equine reflux urges the slidable tubular member to slide toward the stationary tubular member opening the reflux drainage hole to divert equine backflow downwardly through the equine backflow drainage hole preventing passage of equine reflux into the operator's mouth.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: September 16, 2025
    Inventor: Ryan M. Lee
  • Publication number: 20230374529
    Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 23, 2023
    Applicant: CORTEVA AGRISCIENCE LLC
    Inventors: DAVID R. CORBIN, WEI CHEN, STEPHEN NOVAK, RYAN M. LEE, SANDEEP KUMAR, ANDREW ASBERRY, ANDREW F. WORDEN
  • Publication number: 20230183300
    Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.
    Type: Application
    Filed: September 19, 2022
    Publication date: June 15, 2023
    Applicant: CORTEVA AGRISCIENCE LLC
    Inventors: JOEL J. SHEETS, JANNA MAI ARMSTRONG, TRISTAN E. CORAM, AUDREY JANE ETTER, TODD P. GLANCY, TIMOTHY D. HEY, JAMES E. KING, RYAN M. LEE, JIANQUAN LI, GAOFENG LIN, KRISHNA M. MADDURI, THOMAS MEADE, KENNETH NARVA, SEK YEE TAN
  • Patent number: 11634721
    Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: April 25, 2023
    Inventors: David R. Corbin, Wei Chen, Stephen Novak, Ryan M. Lee, Sandeep Kumar, Andrew Asberry, Andrew F. Worden
  • Publication number: 20230117437
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Application
    Filed: October 31, 2022
    Publication date: April 20, 2023
    Applicant: CORTEVA AGRISCIENCE LLC
    Inventors: SANDEEP KUMAR, RYAN M. LEE, STEPHEN NOVAK, ANDREW F. WORDEN
  • Patent number: 11519000
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: December 6, 2022
    Assignee: CORTEVA AGRISCIENCE LLC
    Inventors: Sandeep Kumar, Ryan M. Lee, Stephen Novak, Andrew F. Worden
  • Patent number: 11351344
    Abstract: A rigid hollow tubular adapter releasably attached at a longitudinal nozzle end to a flexible tube during equine nasogastric intubation comprising an annular sleeve having a stationary tubular member and a slidable tubular member. The slidable tubular member is delimited at its ends by the stationary tubular member and a detent member disposed between an equine reflux drainage hole and a longitudinal mouthpiece end. Operator's puffs of airflow through a mouthpiece urges the slidable member to slide toward the detent member closing the equine drainage hole to enable passage of medication into the equine stomach. Equine reflux urges the slidable tubular member to slide toward the stationary tubular member opening the reflux drainage hole to divert equine backflow downwardly through the equine backflow drainage hole preventing passage of equine reflux into the operator's mouth.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: June 7, 2022
    Inventor: Ryan M. Lee
  • Publication number: 20200377899
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Application
    Filed: August 17, 2020
    Publication date: December 3, 2020
    Applicant: Dow AgroSciences LLC
    Inventors: Sandeep Kumar, Ryan M. Lee, Stephen Novak, Andrew F. Worden
  • Patent number: 10781455
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 22, 2020
    Assignee: Dow AgroSciences LLC
    Inventors: Sandeep Kumar, Andrew F. Worden, Stephen Novak, Ryan M. Lee
  • Patent number: 10570182
    Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: February 25, 2020
    Assignee: DOW AGROSCIENCES LLC
    Inventors: Joel J. Sheets, Kenneth Narva, Thomas Meade, Timothy D. Hey, Sek Yee Tan, Audrey Jane Etter, Todd P. Glancy, Janna Mai Armstrong, Tristan E. Coram, Krishna M. Madduri, James E. King, Ryan M. Lee, Gaofeng Lin, Jianquan Li
  • Publication number: 20180163218
    Abstract: Disclosed herein are methods and compositions for the repair of site specific nuclease binding sites by targeted integration and/or targeted excision of one or more sequences into a cell.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 14, 2018
    Applicant: Dow AgroSciences LLC
    Inventors: David H. Corbin, Wei Chen, Stephen Novak, Ryan M. Lee, Sandeep Kumar, Andrew Asberry, Andrew F. Worden
  • Publication number: 20170369539
    Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.
    Type: Application
    Filed: December 16, 2015
    Publication date: December 28, 2017
    Applicant: Dow Agrosciences LLC
    Inventors: Joel J. SHEETS, Kenneth NARVA, Thomas MEADE, Timothy D. HEY, Sek Yee TAN, Audrey Jane ETTER, Todd P. GLANCY, Janna Mai ARMSTRONG, Tristan E. CORAM, Krishna M. MADDURI, James E. KING, Ryan M. LEE, Gaofeng LIN, Jianquan LI
  • Publication number: 20170362600
    Abstract: The current disclosure relates to methods and compositions for improving plant varieties through plant breeding and plant genetics. For instance, the disclosure concerns increasing the recombination frequency of a heterozygous trait genetically linked to a second trait within plants. Further, the disclosure concerns breaking the genetic linkage between a first allele and a second allele.
    Type: Application
    Filed: June 2, 2017
    Publication date: December 21, 2017
    Applicant: Dow AgroSciences LLC
    Inventors: Sandeep Kumar, Andrew F. Worden, Stephen Novak, Ryan M. Lee