Patents by Inventor Ryan Marina

Ryan Marina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND USE OF CHIMERIC PROTEINS
    Publication number: 20230138328
    Abstract: Provided are methods for using chimeric proteins to produce RNA modifications that can be detected by sequencing methods, including methods detecting relative translation rates of various mRNAs. Also provided herein are compositions comprising chimeric proteins, wherein the chimeric proteins comprise a RNA editing protein and a ribosomal protein.
    Type: Application
    Filed: March 12, 2021
    Publication date: May 4, 2023
    Inventors: Eugene Yeo, Kristopher W. Brannan, Ryan Marina, Isaac A. Chaim, Daniel A. Lorenz
  • DIRECTED EDITING OF CELLULAR RNA VIA NUCLEAR DELIVERY OF CRISPR/CAS9
    Publication number: 20230053915
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Application
    Filed: July 11, 2022
    Publication date: February 23, 2023
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9
    Patent number: 11453891
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: September 27, 2022
    Assignee: The Regents of the University of California
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • DIRECTED EDITING OF CELLULAR RNA VIA NUCLEAR DELIVERY OF CRISPR/CAS9
    Publication number: 20180334685
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 22, 2018
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles