Abstract: Provided herein are engineered hCMV gB polypeptides. In some aspects, the engineered gB polypeptides exhibit enhanced conformational stability and/or antigenicity. Methods are also provided for use of the engineered gB polypeptides as diagnostics, in screening platforms, and/or in vaccine compositions.

Abstract: A piece of equipment commonly used in many petrochemical and refinery processes is a pressure swing adsorption (PSA) unit. A PSA unit may be used to recover and purify hydrogen process streams, such as from hydrocracking and hydrotreating process streams. Aspects of the present disclosure are directed to monitoring PSA unit processes for potential and existing issues, providing alerts, and/or adjusting operating conditions to optimize PSA unit life. There are many process performance indicators that may be monitored including, but not limited to, flow rates, chemical analyzers, temperature, and/or pressure. In addition, valve operation may be monitored, including opening speed, closing speed, and performance. The system may adjust one or more operating characteristics to decrease the difference between the actual operating performance in the recent and the optimal operating performance.

Abstract: Adsorbers have many purposes in chemical, gas-processing, and petrochemical plants. Adsorbers may be used to remove components from gas streams. Adsorbers may be subjected to various issues, including but not limited to moisture breakthrough, spent catalyst, too high or too low pressure drop, over or under heating, over or under cooling, too high or too low flow rates, which can affect their performance or result in a shutdown of the adsorbers. Monitoring the adsorbers and the processes using adsorbers may be performed to determine if the adsorbent bed is reaching saturation, other problems are occurring, or if equipment failures are imminent. Monitoring also helps to predict behavior or problems in different adsorbers used in the same plant or in other plants and/or processes.

Abstract: A piece of equipment commonly used in many petrochemical and refinery processes is a pressure swing adsorption (PSA) unit. A PSA unit may be used to recover and purify hydrogen process streams, such as from hydrocracking and hydrotreating process streams. Aspects of the present disclosure are directed to monitoring PSA unit processes for potential and existing issues, providing alerts, and/or adjusting operating conditions to optimize PSA unit life. There are many process performance indicators that may be monitored including, but not limited to, flow rates, chemical analyzers, temperature, and/or pressure. In addition, valve operation may be monitored, including opening speed, closing speed, and performance. The system may adjust one or more operating characteristics to decrease the difference between the actual operating performance in the recent and the optimal operating performance.

Abstract: Adsorbers have many purposes in chemical, gas-processing, and petrochemical plants. Adsorbers may be used to remove components from gas streams. Adsorbers may be subjected to various issues, including but not limited to moisture breakthrough, spent catalyst, too high or too low pressure drop, over or under heating, over or under cooling, too high or too low flow rates, which can affect their performance or result in a shutdown of the adsorbers. Monitoring the adsorbers and the processes using adsorbers may be performed to determine if the adsorbent bed is reaching saturation, other problems are occurring, or if equipment failures are imminent. Monitoring also helps to predict behavior or problems in different adsorbers used in the same plant or in other plants and/or processes.