Abstract: Leak detection user interfaces are provided. In general, a user interface for a pipeline management system can be configured to provide information regarding one or more pipelines to a user. The information can include data gathered using one or more sensors sensing various parameters. The information on the user interface can include results of analysis of the gathered data, such as notifications that the gathered data indicates an anomaly with a pipeline. The notifications of anomalies can be provided on the user interface in real time with the data analysis. Accordingly, the user can trigger one or more corrective actions such as notifying maintenance personnel local to a location of the identified anomaly, remotely controlling the pipeline with the anomaly to close valve(s) and/or other equipment to prevent fluid flow in the pipeline in the area of the detected anomaly, etc.

Abstract: Leak detection user interfaces are provided. In general, a user interface for a pipeline management system can be configured to provide information regarding one or more pipelines to a user. The information can include data gathered using one or more sensors sensing various parameters. The information on the user interface can include results of analysis of the gathered data, such as notifications that the gathered data indicates an anomaly with a pipeline. The notifications of anomalies can be provided on the user interface in real time with the data analysis. Accordingly, the user can trigger one or more corrective actions such as notifying maintenance personnel local to a location of the identified anomaly, remotely controlling the pipeline with the anomaly to close valve(s) and/or other equipment to prevent fluid flow in the pipeline in the area of the detected anomaly, etc.

Abstract: Perforin-2 (P2) is expressed by fibroblasts, microglia and macrophages and was found to be responsible for killing bacteria, for example, Mycobacteria smegmatis, M. avium, Salmonellae, MRSA (drug resistant Stapholococci), E. coli. Compounds identified by screening assays are selected based on the effects of these compounds on P2. Use of these compounds in the treatment of infectious diseases, in particular, bacteria and antibiotic-resistant bacteria is also provided.

Abstract: Methods and compositions are provided to modulate the activity of Perforin-2. Provided herein are various components of the Perforin-2 activation pathway. In specific embodiments, inhibitors of the various components of the Perforin-2 activation pathway are provided which may be employed in various methods, including, but not limited to, the diagnosis and treatment of diseases associated with gut inflammation. Methods of screening for Perforin-2 inhibitors are also provided. Further provided are compounds that increase the ubiquitination of Perforin-2 and thereby increase Perforin-2 activity. Various methods for increasing Perforin-2 activity and for the treatment of infectious disease, in particular bacteria and antibiotic-resistant bacteria, are also provided.

Abstract: Perforin-2 (P2) is expressed by fibroblasts, microglia and macrophages and was found to be responsible for killing bacteria, for example, Mycobacteria smegmatis, M. avium, Salmonellae, MRSA (drug resistant Stapholococci), E coli. Compounds identified by screening assays are selected based on the effects of these compounds on P2. Use of these compounds in the treatment of infectious diseases, in particular, bacteria and antibiotic-resistant bacteria is also provided.

Abstract: Perforin-2 (P2) is expressed by fibroblasts, microglia and macrophages and was found to be responsible for killing bacteria, for example, Mycobacteria smegmatis, M. avium, Salmonellae, MRSA (drug resistant Stapholococci), E coli. Compounds identified by screening assays are selected based on the effects of these compounds on P2. Use of these compounds in the treatment of infectious diseases, in particular, bacteria and antibiotic-resistant bacteria is also provided.

Abstract: A system and method for enriching memories and enhancing emotions about a specific personal event is disclosed. The system allows an easy to use enrichment of memories in terms of emotions and feelings around personal events such as vacations, promotions, sports, celebrations, etc. in form of still images, illustrations, templates, audio, video, and/or data. The invention is a turn-key system that combines broadly available hardware, industrial design, software, proprietary content, user-friendly user interface, distribution, and services tailored towards emotional personal events.