Abstract: In various examples, a deep neural network(s) (e.g., a convolutional neural network) may be trained to detect moving and stationary obstacles from RADAR data of a three dimensional (3D) space. In some embodiments, ground truth training data for the neural network(s) may be generated from LIDAR data. More specifically, a scene may be observed with RADAR and LIDAR sensors to collect RADAR data and LIDAR data for a particular time slice. The RADAR data may be used for input training data, and the LIDAR data associated with the same or closest time slice as the RADAR data may be annotated with ground truth labels identifying objects to be detected. The LIDAR labels may be propagated to the RADAR data, and LIDAR labels containing less than some threshold number of RADAR detections may be omitted. The (remaining) LIDAR labels may be used to generate ground truth data.

Abstract: A valve assembly for a medical device including a container including a first region and a second region, a first fluid inlet fluidly coupled to the first region, a second fluid inlet fluidly coupled to the second region, and a piston assembly disposed within the container. The container is configured to house an agent within the second region, the first fluid inlet is configured to deliver a first portion of pressurized fluid to the first region at a first pressure level, and the second fluid inlet is configured to deliver a second portion of pressurized fluid to the second region at a second pressure level that is less than the first pressure level. The piston assembly includes a valve configured to move from a first position to a second position in response to the piston assembly moving relative to the container.

Abstract: Systems and methods are disclosed that relate to freespace detection using machine learning models. First data that may include object labels may be obtained from a first sensor and freespace may be identified using the first data and the object labels. The first data may be annotated to include freespace labels that correspond to freespace within an operational environment. Freespace annotated data may be generated by combining the one or more freespace labels with second data obtained from a second sensor, with the freespace annotated data corresponding to a viewable area in the operational environment. The viewable area may be determined by tracing one or more rays from the second sensor within the field of view of the second sensor relative to the first data. The freespace annotated data may be input into a machine learning model to train the machine learning model to detect freespace using the second data.

Abstract: The present application relates to compositions and methods for modulating expression of Family with Sequence Similarity 13 Member A (FAM13A) protein. In particular, the present application relates to nucleic acid-based therapeutics for reducing FAM13A gene expression via RNA interference and methods of using such nucleic acid-based therapeutics to reduce abdominal adiposity, reduce body weight, reduce fat mass, improve metabolic parameters including insulin resistance and non-alcoholic steatohepatitis (NASH), and reduce risk of myocardial infarction.

Abstract: A surgical clip applier is provided that includes first and second jaws on a distal end of an elongate shaft, a clip advancing assembly extending through the shaft and configured to advance a distal-most clip from a plurality of clips in the shaft into the first and second jaws. The jaws have opposed inward facing surfaces, and each inward facing surface has a clip track defined therein for receiving and guiding legs of a clip into the first and second jaws. The clip track of at least one of the jaws has at least one deflectable clip retention member disposed therein and configured to apply a biasing force to a leg of a clip disposed within the jaws to thereby retain the clip within the jaws and maintain alignment of the clip with respect to the jaws. The clip track of at least one of the jaws may also have at least one recess or protrusion designed to be complementary to and mate with a protrusion or recess in a clip.

Abstract: A system and method are disclosed herein. The system includes one or more processors and a memory having programming instructions stored thereon, which, when executed by the one or more processors, performs operations. The operations include retrieving historical account activity. The operations further include constructing a training data set that includes the historical inflow data, the historical outflow data, and known forecast information from the historical account activity. The operations further include generating a combined prediction model configured to forecast future inflow activity and future outflow activity. The operations further include receiving current inflow activity, current outflow activity, and current balance information for a user.

Abstract: A carrier laser device assembly is provided in which a visible region of a laser that includes an output portion and/or output portion of a waveguide of the laser is visible to an imaging system when the laser is attached to a carrier. The laser may be burned-in and/or tested prior to attachment to a photonic integrated circuit. The output portion and/or output portion of waveguide may be aligned with a corresponding input portion and/or input portion of a waveguide of the PIC as the laser assembly is being attached to the PIC via imaging of the visible portion by the imaging system.

Abstract: A carrier laser device assembly is provided in which a visible region of a laser that includes an output portion and/or output portion of a waveguide of the laser is visible to an imaging system when the laser is attached to a carrier. The laser may be burned-in and/or tested prior to attachment to a photonic integrated circuit. The output portion and/or output portion of waveguide may be aligned with a corresponding input portion and/or input portion of a waveguide of the PIC as the laser assembly is being attached to the PIC via imaging of the visible portion by the imaging system.

Abstract: Described herein are systems and methods that provide a mechanism to proxy and protect HyperText Transport Protocol/Transport Layer Security (HTTP/TLS) redirection attempts. This technique mirrors an intended target request with a new request, never forwarding the original request from the scanner. This action provides protection to the end target as only key elements of the HTTP request are used while crafting a new HTTP request.

Abstract: A system performs a distributed version control on a data lake. A change to the data lake can be performed within a single atomic commit that defines a set of changes. Commits are built on top of each other and describe incremental changes, which creates a sequence of atomic commits that defines a history of changes. The commits can be identified by hash values, and branches can be defined to refer to commits. A new commit updates a branch head reference to the new commit so that the branch head always refers to the latest version of a chain of commits in the branch. The system can create tags that define, for example, a release version and can merge source commits onto target commits including merging the head of one branch onto the head of another branch.

Abstract: As described below, the present invention features genetically modified immune cells having enhanced anti-neoplasia activity, resistance to immune suppression, and decreased risk of eliciting a graft versus host reaction, or a combination thereof. The present invention also features methods for producing and using these modified immune effector cells.

Abstract: Described herein are systems and methods for abstracted analysis system design for a dynamic API scanning service. The disclosure provides a simplified API scanning service by abstracting underlining security scanning techniques and configurations. This presents a normalized view to users of the service. Both input parameters and scan output data is abstracted from users, and is driven based on logic in the service. By providing this simplified view, users can quickly, and without prior security scanning knowledge, use this service to measure their security exposure and mitigate as needed.

Abstract: An example device comprises: a substrate comprising a waveguide material having a waveguide refractive index (RIWG); a first layer of oxide on the substrate having an RI1 lower than the RIWG; a waveguide on the first oxide layer, the waveguide comprising the waveguide material having the RIWG; a second oxide layer on the waveguide and the first oxide layer, the second oxide layer having a second RI2 higher than the RI1 and less than the RIWG, the first oxide layer, the waveguide and the second oxide layer forming an end face for light coupling, and the waveguide extending inwards from the end face and increasing in effective RI from the end face; and an index matching material on the second oxide layer that encapsulates at least the second oxide layer and the end face, a respective RI of the index matching material being about index matched to the RI1.

Abstract: A self-weighing container for transporting delivery items includes a weight-sensing device that is configured to sense a weight of a delivery item that is placed inside the container; a microcontroller that is connected to the weight-sensing device; and a display that is connected to the microcontroller. When a delivery item is placed in the container, the weight-sensing device produces a signal that corresponds to the weight of the delivery item and the microcontroller receives the signal and determines the weight of the delivery item based on the signal. The microcontroller may transmit an indication of the weight to the display, which displays the weight based on the indication of the weight, or the microcontroller may transmit the weight to a smart phone for display.

Abstract: Techniques to determine a programming language of a set of code based on learned programming language patterns. One technique includes receiving a set of code, generating a pattern map of discovered string patterns from the set of code, comparing the string patterns included within the pattern map against learned programming language patterns included with a master voting map to identify one or more profiled programming languages that utilize the learned programming, language patterns that match the string patterns, generating a score card for the set of code by tallying scores for the one or more profiled programming languages based on the comparing, and determining one or more programming languages used to write the set of code based on the score card.

Abstract: As described below, the present invention features genetically modified immune cells having enhanced anti-neoplasia activity, resistance to immune suppression, and decreased risk of eliciting a graft versus host reaction, or a combination thereof. The present invention also features methods for producing and using these modified immune effector cells.

Abstract: Techniques to determine a programming language of a set of code based on learned programming language patterns. One technique includes receiving a set of code, generating a pattern map of discovered string patterns from the set of code, comparing the string patterns included within the pattern map against learned programming language patterns included with a master voting map to identify one or more profiled programming languages that utilize the learned programming, language patterns that match the string patterns, generating a score card for the set of code by tallying scores for the one or more profiled programming languages based on the comparing, and determining one or more programming languages used to write the set of code based on the score card.

Abstract: A carrier laser device assembly is provided in which a visible region of a laser that includes an output portion and/or output portion of a waveguide of the laser is visible to an imaging system when the laser is attached to a carrier. The laser may be burned-in and/or tested prior to attachment to a photonic integrated circuit. The output portion and/or output portion of waveguide may be aligned with a corresponding input portion and/or input portion of a waveguide of the PIC as the laser assembly is being attached to the PIC via imaging of the visible portion by the imaging system.

Abstract: A precision baking system includes a baking vessel that defines a vertical direction. The baking vessel includes a base wall and at least one sidewall. An aperture is formed in one of the base wall and the sidewall. The precision baking system also includes a temperature probe. The temperature probe includes a tip and a temperature sensor within the tip. The temperature probe is sized to extend through the aperture such that the tip of the temperature probe is spaced from the base wall and the sidewall of the baking vessel when the temperature probe is fully inserted into the baking vessel through the aperture.