Patents by Inventor Ryan Paul

Ryan Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250236631
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S, G13D, Q61H, Q61L or G12C. The compounds have a general Formula I?: wherein the variables of Formula I? are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: April 11, 2025
    Publication date: July 24, 2025
    Applicant: AMGEN INC.
    Inventors: Ryan Paul Wurz, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Xiaofen LI, John STELLWAGEN, Kexue LI, Brian Alan LANMAN, Michael M. YAMANO, Wei ZHAO, Benjamin WIGMAN, Fabien EMMETIERE, Albert K. AMEGADZIE, Christopher P. MOHR, Aaron C. SIEGMUND, Rene RAHIMOFF, Zhichen WU, Adriano BAUER, Andrew SMALIGO, Quentin Tercenio, Qingyian Liu, Shon K. Booker, Jeffrey Jackson
  • Publication number: 20250179077
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S or G12C. The compounds have a general Formula (I): (Formula (I)) wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: February 15, 2023
    Publication date: June 5, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen LI, Imelda HOT, Rene RAHIMOFF, Liping Pettus, Ning Chen, Fabien EMMETIERE, Jeffery Jackson, Yunxiao LI, Francesco Manoni, Primali Navaratne, Andrew Smaligo, John Charles Stellwagen, John Allen
  • Publication number: 20250163064
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S or G12C. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: February 15, 2023
    Publication date: May 22, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen LI, Michael YAMANO, Imelda HOT, Rene RAHIMOFF, Liping Pettus, Jose Medina
  • Patent number: 12293339
    Abstract: A cashless gaming method including receiving payment for a selected gaming ticket having a predefined fixed value, the gaming ticket being redeemable at a cashless-enabled gaming machine for an associated amount of wagerable credits, and issuing the fixed value gaming ticket to the player responsive to receiving the payment.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: May 6, 2025
    Assignee: Aristocrat Technologies Australia Pty Limited
    Inventor: Ryan Paul Hawkins
  • Publication number: 20250123069
    Abstract: Trigger groups for striker-fired firearms have a firing pin assembly connected to a slide and operable to reciprocate between a rearward retracted position and a forward extended position, the firing pin assembly including a retention surface, a trigger assembly including a sear surface configured to selectively engage the retention surface to releasably restrain the firing pin assembly, the firing pin assembly being responsive to the trigger assembly to release from the retracted position to the extended position in response to movement of the trigger assembly from the forward trigger position to the rearward trigger position and to release from the retracted position to the extended position in response to movement of the trigger assembly from the rearward trigger position to the forward trigger position, the trigger assembly including a retainer movable between a clear position and a blocking position.
    Type: Application
    Filed: December 19, 2024
    Publication date: April 17, 2025
    Applicant: Franklin Armory Holdings, Inc.
    Inventor: Ryan Paul Fellows
  • Publication number: 20250125614
    Abstract: A micro grid system comprises a secondary energy source and a power controller. The secondary energy source is associated with a micro grid that includes a fixed or mobile facility, and the secondary energy source is configured to generate first DC power signal. The power controller is in communication with the secondary energy source and an electric grid, and configured to receive first AC power signal from the electric grid and the first DC power signal from the secondary energy source and output a second AC power signal to loads in communication with the power controller. The power controller comprises an AC to DC frequency converter configured to change frequency and/or voltage of the second AC power signal, a processor, and a memory configured to store instructions that, when executed, cause the processor to control the frequency converter to change the frequency and/or voltage of the second AC power signal.
    Type: Application
    Filed: June 4, 2024
    Publication date: April 17, 2025
    Inventors: Paul W. Donahue, Ryan Paul Donahue, Jeffrey Alan Dankworth
  • Publication number: 20250122222
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: August 10, 2022
    Publication date: April 17, 2025
    Applicant: AMGEN INC.
    Inventors: Michael M. YAMANO, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Rene RAHIMOFF, Xiaofen LI, John STELLWAGEN, Francesco MANONI, Kexue LI, Brian Alan LANMAN, Ryan Paul Wurz, Wei ZHAO, Huan RUI, Josephine ESHON
  • Publication number: 20250125613
    Abstract: A microgrid comprises a meter adapter for interconnection to the electric grid, facility loads, and renewable energy resources using connectors, bus bars, and switches. Adapter connectors and internal bus bars and can be stressed with excessive heat rise from heat losses that arise from carrying high currents due to constraints in the physical size and airflow restrictions. Exhaust ports and/or vents are arranged to achieve a chimney cooling effect in such conditions to meet stringent UL requirements against resultant heat rise within a meter adapter.
    Type: Application
    Filed: May 22, 2024
    Publication date: April 17, 2025
    Inventors: Paul W. Donahue, Ryan Paul Donahue, Jeffrey Alan Dankworth
  • Patent number: 12247786
    Abstract: A system including a graphite electrode having a graphite body with first and second opposed ends. The electrode further includes a threaded connector positioned at one of the first or second ends, and a tag coupled to or positioned in the threaded connector, wherein the tag is configured to transmit a signal including information relating to the electrode.
    Type: Grant
    Filed: October 6, 2022
    Date of Patent: March 11, 2025
    Assignee: GrafTech International Holdings Inc.
    Inventors: Pablo Toniolo, Ronald Gerhan, Ryan Paul, James Merzlak, Frank Andrew Messineo, Jr.
  • Publication number: 20250059205
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: April 28, 2022
    Publication date: February 20, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen Li, Michael M. Yamano, Yunxiao Li, Ning Chen, Birgitte Weinreich Husemoen, Sebastian Leth-Petersen, Jose M. Medina, Kexue Li, Liping Pettus, Rene Rahimoff, Primali Vasundera Navaratne, Huan Rui, Christopher P. Mohr
  • Publication number: 20250059179
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: (I) wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: April 28, 2022
    Publication date: February 20, 2025
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Ryan Paul Wurz, Wei Zhao, Xiaofen Li, Michael M. Yamano, Yunxiao Li, Ning Chen, Sebastian Leth-Petersen, Kexue Li, Liping Pettus, Rene Rahimoff, Primali Vasundera Navaratne, Huan Rui
  • Publication number: 20250034167
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula (I): wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: August 10, 2022
    Publication date: January 30, 2025
    Applicant: AMGEN INC.
    Inventors: Michael M. YAMANO, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Rene RAHIMOFF, Xiaofen LI, John STELLWAGEN, Francesco MANONI, Kexue LI, Brian Alan LANMAN, Ryan Paul Wurz, Wei ZHAO, Huan RUI, Josephine ESHON
  • Patent number: 12209827
    Abstract: Trigger groups for striker-fired firearms have a firing pin assembly connected to a slide and operable to reciprocate between a rearward retracted position and a forward extended position, the firing pin assembly including a retention surface, a trigger assembly including a sear surface configured to selectively engage the retention surface to releasably restrain the firing pin assembly, the firing pin assembly being responsive to the trigger assembly to release from the retracted position to the extended position in response to movement of the trigger assembly from the forward trigger position to the rearward trigger position and to release from the retracted position to the extended position in response to movement of the trigger assembly from the rearward trigger position to the forward trigger position, the trigger assembly including a retainer movable between a clear position and a blocking position.
    Type: Grant
    Filed: March 28, 2023
    Date of Patent: January 28, 2025
    Assignee: FRANKLIN ARMORY HOLDINGS, INC.
    Inventor: Ryan Paul Fellows
  • Patent number: 12186731
    Abstract: The present disclosure is directed to metal organic framework materials and uses for such metal organic framework materials. According to one embodiment, a metal organic framework material may include zinc ions, one or more triazoles, and one or more imidazoles. At least a portion of the zinc ions may be coordinated by the triazoles and the imidazoles such that at least a portion of the metal organic framework material forms a crystalline structure belonging to a monoclinic crystal system.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: January 7, 2025
    Assignee: Georgia Tech Research Corporation
    Inventors: Richelle Lyndon, Ryan Paul Lively, David Scott Sholl, Wenqin You
  • Patent number: 12182608
    Abstract: Systems and methods for implementing an automation platform that is configured to analyze computing activities from a plurality of users so as to identify potential automation processes is provided. In one or more examples, a plurality of data collection agents are deployed across a plurality of computing devices and can be configured to collect and record activities performed on the computing device by one or more users of the computing devices. In one or more examples, each agent deployed on a computing device can be configured to transmit the collected data to a central server that can store the collected data in memory. The central server can be configured to collect the data from each agent and can be configured to apply one or more data science algorithms that can be configured to cluster various activities collected by the agents into groups for potential automation.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: December 31, 2024
    Assignee: PwC Product Sales LLC
    Inventors: Shabbir Hussamuddin Alibhai, Ryan Paul Beechey, Joseph Michael Engel, Christopher Ryan Tucci, Thomas Joseph Foth, Antoinette L. Young
  • Publication number: 20240418468
    Abstract: Pistols having a plurality of operating conditions have a frame having a trigger, an elongated slide connected to the frame and having a rear end facing a user, a moving control element on the elongated slide and positioned in a first position when the pistol is in a first operating condition, and positioned in a second condition when the pistol is in a second operating condition, an indicator on the moving control element visible to the rear, indicia on the elongated slide having a first element associated with the first operating condition and a second element associated with the second operating condition, and the indicator being registered with the first element of the indicia when the moving control element is in the first position, and the indicator being registered with the second element of the indicia when the moving control element is in the second position.
    Type: Application
    Filed: August 19, 2024
    Publication date: December 19, 2024
    Applicant: Franklin Armory Holdings, Inc.
    Inventors: Joseph Harrison Haas, Ryan Paul Fellows
  • Publication number: 20240417412
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: August 10, 2022
    Publication date: December 19, 2024
    Applicant: AMGEN INC.
    Inventors: Brian Alan Lanman, Wei Zhao, Ryan Paul Wurz, Primali Vasundera NAVARATNE, Liping PETTUS, Michael M. YAMANO, Ning Chen, Rene RAHIMOFF, Francesco MANONI, John STELLWAGEN
  • Publication number: 20240404373
    Abstract: The present invention relates to gaming machines, systems and methods of gaming. There are a number of different ways available for determining an award by current gaming machines and systems. In this embodiment, a game controller is arranged to determine an award depending on the number of columns spanned by a cluster of symbols and the number of symbol positions in the cluster.
    Type: Application
    Filed: August 9, 2024
    Publication date: December 5, 2024
    Inventors: Ryan Paul Hawkins, Yanis Tsombanidis, Stephanie Johns, Robert Honeycutt
  • Publication number: 20240333789
    Abstract: Systems and methods for providing a seamless automatic repeat request (ARQ) stream are provided. The system can include a plurality of streaming servers, a load balancer, and an ARQ streaming service. The ARQ streaming service obtains encoded content segments and transmits the segments to a plurality of streaming servers. The plurality of streaming servers is configured to transmit the encoded content segments to a client computing device, and a load balancer is implemented between the client computing device and the plurality of streaming servers. When the client computing device sends a response message to the ARQ streaming service while receiving the encoded content segments from one of the plurality of streaming servers, the ARQ streaming service may identify a failure in the streaming server. The ARQ streaming service retransmits lost encoded content segments by switching the streaming path to another streaming server from the plurality of streaming servers.
    Type: Application
    Filed: March 30, 2023
    Publication date: October 3, 2024
    Inventors: Evan Gerald Statton, Bryan Michael Samis, Michael Henry, Ryan Paul Hegar, Sydney Dean Lovely
  • Publication number: 20240314187
    Abstract: A video packaging and origination service can include one or more encoder components that receive content for encoding and transmitting to requesting entities. During the operation of the encoder components, a management service associated with the video packaging and origination service can receive information related to updates or modifications to the encoder components. Responsive to the information, the management service can instantiate and configure an updated encoder. Once the updated encoder component is instantiated and configured, both the updated and target encoder components receive content for streaming, encode content and generating encoding content. Additionally, the updated encoder component can initiate a notification to the target encoder component that a handover will be occurring and begin a negotiation process identifying a handover event.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 19, 2024
    Inventors: Eric Woodruff, Ryan Paul Hegar, Khawaja Salman Shams