Patents by Inventor Ryan Priore

Ryan Priore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11145411
    Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: October 12, 2021
    Assignee: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Heather Kirschner, Ryan Priore, Alan Wilson
  • Publication number: 20210267499
    Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Inventors: Shona STEWART, Serena AUGUSTINE, Jeffrey COHEN, Ryan PRIORE
  • Patent number: 11006868
    Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: May 18, 2021
    Assignee: CHEMIMAGE TECHNOLOGIES LLC
    Inventors: Shona Stewart, Serena Augustine, Jeffrey Cohen, Ryan Priore
  • Publication number: 20180199863
    Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.
    Type: Application
    Filed: November 15, 2017
    Publication date: July 19, 2018
    Inventors: Shona STEWART, Serena AUGUSTINE, Jeffrey COHEN, Ryan PRIORE
  • Patent number: 9844334
    Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: December 19, 2017
    Assignee: ChemImage Technologies LLC
    Inventors: Shona Stewart, Serena Augustine, Jeffrey Cohen, Ryan Priore
  • Patent number: 9464934
    Abstract: The present disclosure provides for a correction filter that may be configured to comprise a predetermined arrangement of thin film layers. This arrangement of thin film layers may be such that it effectively enables a correction filter to generate a predetermined spectral response, wherein said predetermined spectral response is substantially the same as a determined instrument response correction associated with an instrument. The invention of the present disclosure therefore provides for effectively compensating for transmission inefficiencies associated with an instrument without the need for separate reference measurements to determine and correct for instrument response.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: October 11, 2016
    Assignee: Chemimage Technologies LLC
    Inventors: Ryan Priore, John Maier
  • Patent number: 9329086
    Abstract: A portable system and method for analyzing biological tissue samples and detecting analytes associated with tissue oxygenation using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: May 3, 2016
    Assignee: ChemImage Technologies LLC
    Inventors: Patrick J. Treado, Ryan Priore
  • Patent number: 9274046
    Abstract: A method for analyzing organ samples using hyperspectral imaging comprising illuminating an organ sample to generate interacted photons, collecting the interacted photons and passing the interacted photons through a tunable filter. The filtered interacted photons are detected to generate a hyperspectral image. A brightfield image is generated and associated with the hyperspectral image. Spectra from locations of interest are extracted and analyzed to assess a characteristic of the organ sample. A system may comprise an illumination source to illuminate an organ sample and generate interacted photons, a collection optics for collecting the interacted photons and a tunable filter to filter the interacted photons. A detector is configured to detect the filtered photons and generate at least one hyperspectral image. The detector may also be configured to generate at least one brightfield image representative of the organ sample.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: March 1, 2016
    Assignee: ChemImage Corporation
    Inventors: Shona Stewart, Patrick Treado, Heather Kirschner, Alan Wilson, Ryan Priore, Jeffrey Cohen, Serena Augustine
  • Publication number: 20150294076
    Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 15, 2015
    Applicant: CHEMIMAGE CORPORATION
    Inventors: Patrick Treado, Shona Stewart, Heather Kirschner, Ryan Priore, Alan Wilson
  • Patent number: 9157800
    Abstract: A system and method for detecting at least one target of interest using at least two conformal filters in a dual polarization configuration. A plurality of interacted photons are collected from a sample comprising at least one analyte of interest. The plurality of interacted photons are separated into at least a first and second optical component. The first optical component is passed through a first conformal filter and the second optical component is passed through a second conformal filter. A Data set corresponding to each filtered optical component is generated and an optical computation is applied to assess at least one characteristic of the analyte.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: October 13, 2015
    Assignee: ChemImage Technologies LLC
    Inventors: Ryan Priore, Patrick Treado, Matthew Nelson
  • Publication number: 20150133751
    Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.
    Type: Application
    Filed: June 11, 2014
    Publication date: May 14, 2015
    Inventors: Shona STEWART, Serena AUGUSTINE, Jeffrey COHEN, Ryan PRIORE
  • Patent number: 8993964
    Abstract: A system and method for detecting a contaminant in a sample. The contaminant may comprise melamine or a derivative thereof and the sample may comprise a feed material. The method may comprise illuminating a sample to thereby generate a first plurality of interacted photons, collecting the interacted photons, passing the interacted photons through a tunable filter, and detecting the interacted photons to generate a near infrared data set representative of the sample. This near infrared sample may comprise a hyperspectral near infrared image. The method may further comprise fusing said near infrared data set with a Raman data set representative of sample. A system may comprise an illumination source, one or more collection optics, a tunable filter, and a detector configured to generate a near infrared data set. The system may further comprise a second detector configured for generating a Raman data set representative of a sample.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: March 31, 2015
    Assignee: ChemImage Technologies LLC
    Inventor: Ryan Priore
  • Publication number: 20140198315
    Abstract: A system and method for detecting at least one target of interest using at least two conformal filters in a dual polarization configuration. A plurality of interacted photons are collected from a sample comprising at least one analyte of interest. The plurality of interacted photons are separated into at least a first and second optical component. The first optical component is passed through a first conformal filter and the second optical component is passed through a second conformal filter. A Data set corresponding to each filtered optical component is generated and an optical computation is applied to assess at least one characteristic of the analyte.
    Type: Application
    Filed: January 15, 2014
    Publication date: July 17, 2014
    Applicant: Chemlmage Corporation
    Inventors: Ryan Priore, Patrick Treado, Matthew Nelson
  • Publication number: 20140093147
    Abstract: A method for analyzing organ samples using hyperspectral imaging comprising illuminating an organ sample to generate interacted photons, collecting the interacted photons and passing the interacted photons through a tunable filter. The filtered interacted photons are detected to generate a hyperspectral image. A brightfield image is generated and associated with the hyperspectral image. Spectra from locations of interest are extracted and analyzed to assess a characteristic of the organ sample. A system may comprise an illumination source to illuminate an organ sample and generate interacted photons, a collection optics for collecting the interacted photons and a tunable filter to filter the interacted photons. A detector is configured to detect the filtered photons and generate at least one hyperspectral image. The detector may also be configured to generate at least one brightfield image representative of the organ sample.
    Type: Application
    Filed: December 3, 2013
    Publication date: April 3, 2014
    Applicant: Chemlmage Corporation
    Inventors: Shona Stewart, Patrick Treado, Heather Kirschner, Alan Wilson, Ryan Priore, Jeffrey Cohen, Serena Augustine
  • Publication number: 20140016116
    Abstract: The present disclosure provides for a system and method for assessing chronic exposure of a biological sample, such as a bodily fluid, to an analyte of interest. A biological sample may be illuminated to thereby generate a one or more pluralities of interacted photons. These interacted photons may be detected to thereby generate one or more spectroscopic data sets representative of a biological sample. Spectroscopic data sets generated may be compared to at least one reference data set. Each reference data set may be associated with a known exposure to a known analyte. The present disclosure contemplates that the system and method disclosed herein may be used to analyze exposure of biological samples to at least one analyte over time. Data sets may be obtained at various time intervals to assess changes in a molecular composition as a result of chronic exposure to an analyte.
    Type: Application
    Filed: June 28, 2013
    Publication date: January 16, 2014
    Inventors: John Maier, Jeffrey Cohen, Ryan Priore
  • Publication number: 20130321813
    Abstract: A portable system and method for analyzing biological tissue samples and detecting analytes associated with tissue oxygenation using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 5, 2013
    Inventors: Patrick J. Treado, Ryan Priore
  • Patent number: 8374801
    Abstract: A system and method for determining at least one geometric property of a particle in a sample. A sample is irradiated to thereby generate Raman scattered photons. These photons are collected to generate a Raman chemical image. A first threshold is applied wherein the first threshold is such that all particles in the sample are detected. A particle in the sample is selected and a second threshold is applied so that at least one geometric property of the selected particle can be determined. At least one spectrum representative of the selected particle is analyzed to determine whether or not it is a particle of interest. The step of determining a second threshold may be iterative and automated via software so that candidate second thresholds are applied until a satisfactory result is achieved.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: February 12, 2013
    Assignee: ChemImage Corporation
    Inventors: Michael Fuhrman, Ryan Priore, Oksana Olkhovyk, Oksana Klueva
  • Publication number: 20130027701
    Abstract: The present disclosure provides for a correction filter that may be configured to comprise a predetermined arrangement of thin film layers. This arrangement of thin film layers may be such that it effectively enables a correction filter to generate a predetermined spectral response, wherein said predetermined spectral response is substantially the same as a determined instrument response correction associated with an instrument. The invention of the present disclosure therefore provides for effectively compensating for transmission inefficiencies associated with an instrument without the need for separate reference measurements to determine and correct for instrument response.
    Type: Application
    Filed: January 11, 2012
    Publication date: January 31, 2013
    Applicant: ChemImage Corporation
    Inventors: Ryan Priore, John Maier
  • Publication number: 20130003044
    Abstract: The present disclosure provides for a system and method for assessing chronic exposure of a biological sample, such as a bodily fluid, to an analyte of interest. A biological sample may be illuminated to thereby generate a one or more pluralities of interacted photons. These interacted photons may be detected to thereby generate one or more spectroscopic data sets representative of a biological sample. Spectroscopic data sets generated may be compared to at least one reference data set. Each reference data set may be associated with a known exposure to a known analyte. The present disclosure contemplates that the system and method disclosed herein may be used to analyze exposure of biological samples to at least one analyte over time. Data sets may be obtained at various time intervals to assess changes in a molecular composition as a result of chronic exposure to an analyte.
    Type: Application
    Filed: July 3, 2012
    Publication date: January 3, 2013
    Applicant: Chemlmage Corporation
    Inventors: John Maier, Jeffrey Cohen, Ryan Priore
  • Publication number: 20120229796
    Abstract: A system and method for detecting a contaminant in a sample. The contaminant may comprise melamine or a derivative thereof and the sample may comprise a feed material. The method may comprise illuminating a sample to thereby generate a first plurality of interacted photons, collecting the interacted photons, passing the interacted photons through a tunable filter, and detecting the interacted photons to generate a near infrared data set representative of the sample. This near infrared sample may comprise a hyperspectral near infrared image. The method may further comprise fusing said near infrared data set with a Raman data set representative of sample. A system may comprise an illumination source, one or more collection optics, a tunable filter, and a detector configured to generate a near infrared data set. The system may further comprise a second detector configured for generating a Raman data set representative of a sample.
    Type: Application
    Filed: March 10, 2011
    Publication date: September 13, 2012
    Applicant: Chemlmage Corporation
    Inventor: Ryan Priore