Patents by Inventor Ryan R. Klein

Ryan R. Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enhancing catalytic activity of a lipase
    Patent number: 9416383
    Abstract: Methods for enhancing a biological activity, for example, catalytic activity, of a lipase, are provided. In some embodiments, the methods include the step of alkylating one or more cysteine residues present within the lipase. Also provided are modified polypeptides for which a biological activity is enhanced by the disclosed methods, methods for using the disclosed polypeptides, including for the transesterification of renewable oils to produce a biofuel, and cell free systems that include a lipase, to which one or more moieties, such as steroidal moieties, are conjugated.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: August 16, 2016
    Assignee: University of North Carolina at Chapel Hill
    Inventors: Dhiren R. Thakker, Ryan R. Klein
  • ACTIVATED LIPASES AND METHODS OF USE THEREFOR
    Publication number: 20100330628
    Abstract: Methods for enhancing a biological (e.g., catalytic) activity of a lipase, are provided. In some embodiments, the methods include the step of alkylating one or more cysteine residues present within the lipase. Also provided are modified polypeptides for which a biological activity is enhanced by the disclosed methods, methods for using the disclosed polypeptides, including for the transesterification of renewable oils to produce a biofuel, and cell free systems that include a lipase, to which one or more moieties, such as steroidal moieties, are conjugated.
    Type: Application
    Filed: April 28, 2008
    Publication date: December 30, 2010
    Inventors: Dhiren R. Thakker, Ryan R. Klein