Patents by Inventor Ryan SOWELL

Ryan SOWELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression constructs and uses thereof
    Patent number: 12780890
    Abstract: The present disclosure relates to an isolated polynucleotide comprising a sequence that encodes an interleukin (IL)-12 molecule, and a delivery system that can carry the polynucleotides. The disclosure also includes methods of making the polynucleotides and methods of treatment using the same.
    Type: Grant
    Filed: January 10, 2022
    Date of Patent: November 3, 2026
    Assignee: STRAND THERAPEUTICS INC.
    Inventors: Tasuku Kitada, Jacob Becraft, Ryan Sowell, Jaspreet Khurana, Anna Simon, Joseph Barberio, Weiyu Zhao, Alexander Lemaire, Aalok Shah
  • LIPID NANOPARTICLES COMPRISING VENEZUELAN EQUINE ENCEPHALITIS (VEE) REPLICON AND USES THEREOF
    Publication number: 20250152737
    Abstract: The present disclosure relates to lipid nanoparticles (LNPs) comprising VEE replicon, wherein the LNPs are useful for selectively reducing and/or avoiding the expression of a payload within the liver. The present disclosure also relates to the use of such LNPs to treat various diseases and disorders.
    Type: Application
    Filed: April 26, 2023
    Publication date: May 15, 2025
    Applicant: Strand Therapeutics Inc.
    Inventors: Ryan SOWELL, Rio BOOTHELLO, Wuhbet ABRAHAM, Weiyu ZHAO, Nandita MENON, Aalok SHAH, Prashant NAMBIAR, Tasuku KITADA
  • EXPRESSION CONSTRUCTS AND USES THEREOF
    Publication number: 20240166707
    Abstract: The present disclosure relates to an isolated polynucleotide comprising a sequence that encodes an interleukin (IL)-12 molecule, and a delivery system that can carry the polynucleotides. The disclosure also includes methods of making the polynucleotides and methods of treatment using the same.
    Type: Application
    Filed: January 10, 2022
    Publication date: May 23, 2024
    Applicant: STRAND THERAPEUTICS INC.
    Inventors: Tasuku KITADA, Jacob BECRAFT, Ryan SOWELL, Jaspreet KHURANA, Anna SIMON, Joseph BARBERIO, Weiyu ZHAO, Alexander LEMAIRE, Aalok SHAH
  • LIPID NANOPARTICLE COMPRISING MODIFIED NUCLEOTIDES
    Publication number: 20230295257
    Abstract: The present disclosure relates to a lipid nanoparticle comprising (i) one or more types of lipid; and (ii) a modified mRNA comprising a sequence that encodes an interleukin (IL)-12 molecule, wherein the lipid nanoparticle is capable of triggering immunogenic cell death, and methods of treatment using the same
    Type: Application
    Filed: July 26, 2021
    Publication date: September 21, 2023
    Applicant: STRAND THERAPEUTICS INC.
    Inventors: Jacob BECRAFT, Ryan SOWELL, Jaspreet KHURANA, Tasuku KITADA