Abstract: Provided herein are, inter alia, biosensor recombinant proteins (e.g. ratiometric Ras activity reporter (RasAR)), which provide quantitative measurement of Ras activity in living cells with high spatiotemporal resolution. The biosensor recombinant proteins provided herein include, for example, a novel pseudoligand and are, inter alia, useful for detecting a Ras protein and activity of a Ras protein in a cell.

Abstract: Systems are provided for a system of an integrated suite of software applications platform for an aircraft. An applications layer of operational applications for a user that includes a safety application kit provides information about diversions, weather avoidance, and standard operating procedures (SOP) for the aircraft, an efficiency application kit that provides information about short-cuts to a flight plan, flight level advisories, and cost index advisories for the aircraft, an automation application kit that provides information about flight logs, technical logs, checklists, flight planning and flight summary for the aircraft, and a dispatcher application kit that provides information about re-routing advisories, wind status, flight dispatch and following traffic status for the aircraft. The system has a data access layer that provides access to relevant databases in support of the applications layer.

Abstract: A vehicular seat (10) including a seat bottom (12) and a seat back (14). In one embodiment, the seat bottom (12) and seat back (14) are formed from a blow molded frame (16) including side walls (18) extending generally upwardly from a bottom panel (20). A support mat (32) comprising fabric/rubber webbing extends across a central cut-out region (28) in the bottom panel (20) and supports an inflatable cushion (48) comprising a series of air cells (50). An extensible upholstery or trim cover layer (56) covers the inflatable cushion (48) and is joined to the frame (16). In a second embodiment, the seat bottom (12) and seat back (14) are formed from a blow molded shell (62). An intermediate layer (64) of plastics material is provided on the shell (62) beneath an upholstery layer (68). An opening in the shell (62) allows the intermediate layer (64) to be expanded outwardly from the shell (62) as the pressure within the shell (62) is increased.

Abstract: A vehicular seat (10) including a seat bottom (12) and a seat back (14). In one embodiment, the seat bottom (12) and seat back (14) are formed from a blow molded frame (16) including side walls (18) extending generally upwardly from a bottom panel (20). A support mat (32) comprising fabric/rubber webbing extends across a central cut-out region (28) in the bottom panel (20) and supports an inflatable cushion (48) comprising a series of air cells (50). An extensible upholstery or trim cover layer (56) covers the inflatable cushion (48) and is joined to the frame (16). In a second embodiment, the seat bottom (12) and seat back (14) are formed from a blow molded shell (62). An intermediate layer (64) of plastics material is provided on the shell (62) beneath an upholstery layer (68). An opening in the shell (62) allows the intermediate layer (64) to be expanded outwardly from the shell (62) as the pressure within the shell (62) is increased.