Abstract: A security apparatus, a security system that uses the security apparatus, and a method of using the securing apparatus to secure a portable electronic device to an immovable object. The security apparatus comprises a combination locking mechanism with dials and tumblers, a body coupled to the dials, a reset device coupled to the tumblers, and a reset key configured to interact with the reset device to allow the user to reset the combination associated with the combination locking mechanism.

Abstract: Selected benzomorpholine compounds are effective for prophylaxis and treatment of diseases, such as VEGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A security apparatus, a security system that uses the security apparatus, and a method of using the securing apparatus to secure a portable electronic device to an immovable object. The security apparatus comprises a combination locking mechanism with dials and tumblers, a body coupled to the dials, a reset device coupled to the tumblers, and a reset key configured to interact with the reset device to allow the user to reset the combination associated with the combination locking mechanism.

Abstract: The present invention relates to chemical compounds having a general formula I wherein A1-8, D?, L1, L2, R1, R6-8 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

Abstract: A security apparatus for use with a portable electronic device with an aperture. The security apparatus includes a head including a housing, an engagement element extending from the housing, a first stabilizing element extending from the housing, and can have a second stabilizing element extending from the housing. The first stabilizing element extends out of the housing a first length and the second stabilizing element extends out of the housing a second length.

Abstract: The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various inflammatory, fibrotic and/or mast cell mediated diseases such as mastocytosis. The compounds have a general Formula I wherein A0-3 and R1-6 are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.

Abstract: The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various inflammatory, fibrotic and/or mast cell mediated diseases such as mastocytosis. The compounds have a general Formula I wherein A1-3, R1 and R3-6 are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.

Abstract: A cargo transportation device includes a lift assembly for raising and lowering cargo and an operator cabin in which an operator controls the lift assembly. A load backrest is coupled to the cabin, and an automatic data collection device, which is configured to interrogate wireless communication devices, is coupled to the load backrest. The cargo transportation device includes a computing device having logic for controlling the automatic data collection device and logic for controlling the lift assembly, and a display device in communication with the computing device. The display device is coupled to the cabin and configured to provide the operator with information from the computing device.

Abstract: The present invention relates to compounds of Formula I or a stereomer, a tautomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof, pharmaceutical formulations containing the compounds, methods of treatments using the compounds, for example, protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders and methods of preparing medicaments comprising the compounds.

Abstract: The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation, cancer and related conditions. The compounds have a general Formula I wherein A1, A2, A3, B, R1, R2, R3 and R4 are defined herein. Accordingly, the invention also comprises pharmaceutical compositions comprising the compounds of the invention, methods for the prophylaxis and treatment of kinase mediated diseases using the compounds and compositions of the invention, and intermediates and processes useful for the preparation of compounds of the invention.

Abstract: The present invention relates to furanopyridine compounds having the general Formula I: and stereoisomers, tautomers, solvates, pharmaceutically acceptable salts and derivatives, and prodrugs thereof.

Abstract: A method processes a gel monolith comprising pores filled with liquid, an inner region, and an outer region. The method includes removing a portion of the liquid from the pores of the gel monolith while both the inner and outer regions of the gel monolith remain wet. The method further includes shrinking the volume of the gel monolith during the removal of a portion of the liquid, with the gel monolith becoming correspondingly more dense. The method further includes subsequently removing substantially all of the remaining liquid from the pores of the gel monolith. Subsequently removing substantially all of the remaining liquid includes modulating a temperature gradient between the outer region and the inner region.

Abstract: Systems and techniques relating to a microscope storage unit. In one implementation, a storage unit includes a base, a top and multiple receptacles configured between the base and the top. Each receptacle is configured to house a microscope. The storage unit includes multiple charging devices, where each charging device is configured to recharge a battery of a battery-powered microscope. An electrical cord can be electrically connected to the multiple charging devices, and include a plug configured to mate with an electrical outlet to supply electrical power to the charging devices. One or more wheels can be connected to a lower surface of the base.

Abstract: Systems and techniques relating to a microscope with an adjustable stage are described. A microscope includes a base, a support arm attached to and extending upwardly from the base, a head attached to the support arm, the head including a lens, and an eyepiece attached to the head. A stage is releasably attachable to the support arm between the head and the base at multiple locations, providing multiple working distances between a lower surface of the head and an upper surface of the stage. When the stage is attached to the support arm at a location, a working distance between the lower surface of the head and the upper surface of the stage is further adjustable to an either greater or lesser working distance. In another embodiment, microscopic and macroscopic viewing can both be provided using a lens changer with multiple lens positioned radially about an axis of rotation.

Abstract: A method processes a gel monolith comprising pores filled with liquid, an inner region, and an outer region. The method includes removing a portion of the liquid from the pores of the gel monolith while both the inner and outer regions of the gel monolith remain wet. The method further includes shrinking the volume of the gel monolith during the removal of a portion of the liquid, with the gel monolith becoming correspondingly more dense. The method further includes subsequently removing substantially all of the remaining liquid from the pores of the gel monolith. Subsequently removing substantially all of the remaining liquid includes modulating a temperature gradient between the outer region and the inner region.

Abstract: This purpose of this device is to protect an after market car stereo, of DIN size, installed in a vehicle from environmental pollutants, conditions, and theft. The device has tapering sides, which will allow it to fit onto after market car stereos installed in cars where there is minimal distance between the after market stereo and the dash of the car. The composition of the device is a multiple thickness plastic. This is what allows the device, when applied in a vehicle with an after market car stereo installed, to give the car a look of having no stereo installed. There is medium density foam located in the inside of the back plate, which acts as both an insulator and a filter against environmental pollutants and conditions.