Abstract: In various implementations, berberine metabolites, such as dihydroberberine and/or tetrahydroberberine, may be administered to manage blood glucose levels, increase ketone levels (e.g., blood concentration of ketones), and/or for therapeutic purposes in humans. The administration of a pharmaceutically effective amount of berberine metabolites, such as dihydroberberine, may reduce fasting blood glucose levels, improve glucose tolerance, and/or improve blood ketone response. In some implementations, berberine metabolites may be administered with one or more other compounds.

Abstract: Systems and methods are provided for adaptive data replication. A first data object is stored. One or more first network characteristics of a communication network are detected. A first replication mode is triggered (e.g., a single-master replication mode) based on the one or more first network characteristics of the communication network. The single-master replication may be configured to facilitate real-time synchronizations (e.g., for critical updates). One or more second network characteristics of the communication network are detected. A second replication mode (e.g., a multi-master replication mode) is triggered based on the one or more second network characteristics. The second replication may be configured to facilitate a delayed synchronization (e.g., for non-critical updates) of the first data object and the second data object using the second update file.

Abstract: A system receives medical data from multiple physiological monitor devices in various forms and formats. A data normalization process identifies each attribute type in the medical data reported by each device and assigns a unique attribute identifier. All parameters associated with an attribute are also identified and assigned a unique parameter identifier. The data normalization process uses this information to create a standardized data set for analysis. A rules processing engine applies alert and reporting rules to the standardized data set to generate a patient report and alerts for patient data that is beyond thresholds defined by the alert rules. The system provides default alert rules that may be overridden by clinic rule or manufacturer rules. Artificial intelligence (AI) principles may be applied using training set(s) of data to teach the rules processing engine to use the AI alert rules for data analysis.

Abstract: The present disclosure pertains to compositions and methods for the treatment and/or prevention of one or more of obesity, diabetes, metabolic syndrome, Alzheimer's disease, Chronic Fatigue Syndrome (CFS), aging, fibromyalgia, dyslipidemia, hypercholesterolemia, dyslipidemia, Parkinson's disease, migraines, Traumatic Brain Injury (TBI), Attention Deficit Disorder (ADD)/Attention Deficit Hyperactivity Disorder (ADHD), Cancer, Cardiovascular Disease (CVD)/Coronary Artery Disease (CAD), Chronic Pain, neuralgia, depression, amyotrophic lateral sclerosis (ALS), and epilepsy, Insufficient Cellular Energy (ICE) and mitochondrial dysfunction. The present disclosure also pertains to methods for increasing mental and/or physical performance levels and/or decreasing exertion during exercise in a subject by the administration of C5 ketones.

Abstract: A hearing health monitoring system, noise mitigating system, and method for monitoring hearing health are provided.

Abstract: Methods and compositions related to solid dosage forms that facilitate the oral delivery of bacteria and/or agents of bacterial origin are provided herein.

Abstract: Described are systems and methods to provide an interactive, livestream platform where multiple participants can connect and engage with a host of an interactive, livestream session and/or other participants engaged in the session. According to exemplary implementations, a live, interactive, livestream session (e.g., by a content creator) can be created among a client device associated with a host and multiple client devices associated with participants/attendees. Further, participants/attendees of the live, interactive, livestream session may request direct interaction and/or engagement with the host of the interactive, livestream session, and a priority can be determined for each participant/attendee based on user history between the participant/attendee and the host, crowd sourced voting of the participants/attendees, access type, and the like.

Abstract: Described are systems and methods to extract image segments from an image and include those extracted image segments in a collage. The origin information, such as the source image, source image location, etc., from which the extracted image segment is generated is maintained as metadata so that interaction with the extracted image segment on the collage can be used to determine and/or return to the origin of the extracted image segment. Collages may be updated, shared, adjusted, etc., by the creator of the collage or other users.

Abstract: A method and system for improving e-commerce that is directed at improving landing pages for consumer products. Using long tail query phrases, the method and system generates more detailed landing pages that will assist in providing more information to consumers.

Abstract: Disclosed are systems and methods that authenticate non-fungible tokens (“NFT”) and/or digital data represented by or pointed to by an NFT. In some implementations, authentication may be with respect to an existing NFT. In other implementations, authentication may be with respect to an NFT that is being created. The disclosed implementations may compare a candidate and/or candidate NFT data with existing NFTs and/or existing NFT data to determine if the candidate NFT and/or candidate NFT data is similar to other NFTs and/or other NFT data of another NFT, which may exist on any of many different blockchains.

Abstract: A mobile music store assembly includes a housing base; a first housing member that is selectively movable relative to the housing base between a first position wherein the mobile music store assembly is in a closed configuration, and a second position wherein the mobile music store assembly is in an open configuration; and a second housing member that is selectively movable relative to the first housing member and the housing base between a first position wherein the mobile music store assembly is in the closed configuration, and a second position wherein the mobile music store assembly is in the open configuration. The mobile music store assembly can further include a music player that is positioned substantially within the housing assembly. The music player is only accessible when the mobile music store assembly is in the open configuration.

Abstract: The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds.

Abstract: The disclosure provides methods and systems for producing single cell RNA sequencing data. Single nucleotide polymorphisms (SNPs) identified in such data can be used to distinguish subpopulations of cells within a mixed population.

Abstract: Systems, methods, and computer software are disclosed for receiving a video stream and acquiring images capturing at least a portion of a shape representative of a radiation field generated by a radiation delivery system that includes a radiation source configured to deliver the radiation beam, the acquired images extracted from the video stream.

Abstract: The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds.

Abstract: A mobile music store assembly includes a housing base; a first housing member that is selectively movable relative to the housing base between a first position wherein the mobile music store assembly is in a closed configuration, and a second position wherein the mobile music store assembly is in an open configuration; and a second housing member that is selectively movable relative to the first housing member and the housing base between a first position wherein the mobile music store assembly is in the closed configuration, and a second position wherein the mobile music store assembly is in the open configuration. The mobile music store assembly can further include a music player that is positioned substantially within the housing assembly. The music player is only accessible when the mobile music store assembly is in the open configuration.

Abstract: A measurement system and methods for collecting measurement data for features of ceramic matrix composite (CMC) components are provided. In one aspect, the system and methods provided herein can be utilized to collect measurement data for a cooling hole of a CMC component. The measurement system includes a sensor system that includes a chromatic confocal sensor and a charged coupled device. The chromatic confocal sensor emits stacked cones of light each having an associated wavelength. The stacked cones are moved over a target surface of the CMC component and the charged coupled device measures one or more characteristics associated with the reflected light. The characteristics are then used by a computing device to generate a measurement data file representative of the geometric profile of the cooling hole. A rotary table system can position the CMC component to present the cooling hole at different orientations.