Abstract: Provided is the present invention focusing on roles of IL-26 present in humans but not in mice by characterizing molecular mechanisms involved in interspecies differences in terms of efficacy of EGFR-TKI. The present inventors found that human cancers are exposed to IL-26 in a tumor microenvironment (TME), activating the EGFR-TKI bypass pathway, while suppression of IL-26 overcomes EGFR-TKI resistance in cancers. Furthermore, the present inventors identified EphA3 as a new functional receptor for IL-26 of TNBC. Therefore, the present invention provides a pharmaceutical composition for use in combination with an anticancer drug for treating cancer in a patient, the pharmaceutical composition containing a drug that reverses resistance to the anticancer drug by IL-26 as an active ingredient. Furthermore, the present invention provides a humanized anti-IL-26 antibody, and a therapeutic or preventive agent for refractory immune disorders or cancer using the antibody.

Abstract: According to one embodiment, a wearable device includes a first user interface and a display. An electronic device includes a second user interface and causes the display to display a home screen. The home screen displayed in the display is divided into variable-sized first, second, and third areas. One of the first area, the second area, and the third area is selectable by an operation from the first user interface or the second user interface. The selected area is larger than non-selected areas among the first area, the second area, and the third area. A central icon in the selected area is larger than other icons in the selected area. A display format of the central icon in the selected area is different from a display format of the other icons in the selected area.

Abstract: According to one embodiment, an electronic device includes a character input controller. The character input controller displays a software keyboard including a set of input areas. Each input area of the set includes objects each representing a character. The set of input areas is arranged adjacent to one another in a first direction. The character input controller moves an active input area in the first direction or in a second direction opposite to the first direction, in response to a first operation or a second operation, and changes a character of an active object displayed in the active input area into another character in the active input area, in response to a third operation or a fourth operation.

Abstract: According to one embodiment, an electronic device includes a character input controller. The character input controller displays a software keyboard including a set of input areas. Each input area of the set includes objects each representing a character. The set of input areas is arranged adjacent to one another in a first direction. The character input controller moves an active input area in the first direction or in a second direction opposite to the first direction, in response to a first operation or a second operation, and changes a character of an active object displayed in the active input area into another character in the active input area, in response to a third operation or a fourth operation.

Abstract: According to one embodiment, an electronic apparatus includes an object display controller. The object display controller scrolls an object selection screen in a first direction when an operation device is operated to designate a second direction perpendicular to the first direction, by moving, in the second direction, a first object located at a first end of a line of a set of objects which are lined in the first direction on the object selection screen to disappear the first object from the object selection screen, and by displaying a second object different from any one of the set of objects to appear at a second end of the line of the set of objects on the object selection screen from a third direction opposite to the second direction.

Abstract: According to one embodiment, a wearable device includes a first user interface and a display. An electronic device includes a second user interface and causes the display to display a home screen. The home screen displayed in the display is divided into variable-sized first, second, and third areas. One of the first area, the second area, and the third area is selectable by an operation from the first user interface or the second user interface. The selected area is larger than non-selected areas among the first area, the second area, and the third area. A central icon in the selected area is larger than other icons in the selected area. A display format of the central icon in the selected area is different from a display format of the other icons in the selected area.

Abstract: It is intended to provide an anti-human CD26 antibody which permits analysis, etc., of the expression of CD26 in cancer tissues, immune tissues, or the like, for example, in order to select a patient applicable to treatment or to monitor therapeutic effects, and can also be used in immunostaining. The present invention relates to an anti-human CD26 monoclonal antibody or an antigen-binding fragment thereof, binding to an epitope which is recognized by a monoclonal antibody produced by a hybridoma deposited under Accession No. NITE BP-01642, a hybridoma deposited under Accession No. NITE BP-01643, or a hybridoma deposited under Accession No. NITE BP-01644.

Abstract: It is intended to provide an anti-human CD26 antibody which permits analysis, etc., of the expression of CD26 in cancer tissues, immune tissues, or the like, for example, in order to select a patient applicable to treatment or to monitor therapeutic effects, and can also be used in immunostaining. The present invention relates to an anti-human CD26 monoclonal antibody or an antigen-binding fragment thereof, binding to an epitope which is recognized by a monoclonal antibody produced by a hybridoma deposited under Accession No. NITE BP-01642, a hybridoma deposited under Accession No. NITE BP-01643, or a hybridoma deposited under Accession No. NITE BP-01644.

Abstract: A method for purifying a pyrazolinone derivative comprising a step of mixing a solution containing a mixture containing the pyrazolinone derivative and a good solvent which can dissolve the pyrazolinone derivative with a poor solvent to crystallize the pyrazolinone derivative.

Abstract: An information processing apparatus includes: a wireless communication module which performs a wireless communication with a counterpart apparatus; a memory which stores a first application and a plurality of second applications, the first application for performing data communication with the counterpart apparatus through the wireless communication, and the second applications placed in a higher level than the first application; a controller which activates one of the second applications for the counterpart apparatus; and an indicator which makes an indication according to the wireless communication. The controller determines whether the activated one of the second applications is accessible the indicator.

Abstract: A mixing apparatus (10A) comprises a tubular mixing section (1) for mixing a combustible gas and a combustion supporting gas; a combustible gas supply port at one end (1a); a combustible gas transport device (3) for supplying the combustible gas into the tubular mixing section (1) from the combustible gas supply port; a mixed gas outlet port of the combustible gas and the combustion supporting gas at the other end (1b); and a combustion supporting gas supply tube (5) connected to the tubular mixing section (1) between the one end (1a) and the other end (1b) for supplying the combustion supporting gas into the tubular mixing section (1) from a combustion supporting gas supply port (5a). The combustible gas transport device (3) can control a flow velocity of the combustible gas at the combustion supporting gas supply port (5a) not less than a combustion velocity of the mixed gas.

Abstract: A mixer (10) for mixing a combustible gas and a combustion supporting gas comprises a tubular mixing section (1) which extends between one end (1a) having a combustible gas supply port (2) and the other end (1b) having a mixed gas discharge port (3); and a combustion supporting gas supply tube (4) which is inserted into the tubular mixing section (1) between the one end (1a) and the other end (1b) of the tubular mixing section (1) and has a combustion supporting gas supply port (5) at its tip (4a) to open towards the other end (1b) of the tubular mixing section (1). A juxta-tip part (4b) of the combustion supporting gas supply tube (4) has an outer shape tapered towards the combustion supporting gas supply port (5) at the tip (4a).

Abstract: A mixer (10) for mixing a combustible gas and a combustion supporting gas comprises a tubular mixing section (1) which extends between one end (1a) having a combustible gas supply port (2) and the other end (1b) having a mixed gas discharge port (3); and a combustion supporting gas supply tube (4) which is inserted into the tubular mixing section (1) between the one end (1a) and the other end (1b) of the tubular mixing section (1), is closed at its tip (4a), and has at least one combustion supporting gas supply port at its juxta-tip lateral part (4b). A central axis of the combustion supporting gas supply tube (4) at the juxta-tip lateral part (4b) is generally parallel to a longitudinal direction of the tubular mixing section (1).

Abstract: A method for purifying a pyrazolinone derivative comprising a step of mixing a solution containing a mixture containing the pyrazolinone derivative and a good solvent which can dissolve the pyrazolinone derivative with a poor solvent to crystallize the pyrazolinone derivative.

Abstract: According to one embodiment, an electronic apparatus comprises a communication device, a first controller, a second controller, and a player. The communication device has a close proximity wireless communication function. The first controller establishes connection between a wireless device and the communication device in a proximity state. The second controller connects the electronic apparatus to a server through the close proximity wireless communication function and a wireless communication function of the wireless device. The player plays a content received from the server through the close proximity wireless communication function and the wireless communication function of the wireless device, to halt playing the content when the proximity state is released during the playing, and resume playing the content when the proximity state is restored.

Abstract: An information processing apparatus includes: a wireless communication module which performs a wireless communication with a counterpart apparatus; a memory which stores a first application and a plurality of second applications, the first application for performing data communication with the counterpart apparatus through the wireless communication, and the second applications placed in a higher level than the first application; a controller which activates one of the second applications for the counterpart apparatus; and an indicator which makes an indication according to the wireless communication. The controller determines whether the activated one of the second applications is accessible the indicator.

Abstract: According to one exemplary embodiment, an information processing apparatus is provided with: a wireless communication module configured to perform a wireless communication with a counterpart communication apparatus that is detected to be in a given range from the wireless communication module; and a controller configured to control the wireless communication. The controller is configured to determine whether a condition for starting to perform the wireless communication is satisfied when the counterpart communication apparatus is detected by the wireless communication module, and to control the wireless communication module to start performing the wireless communication when the controller determines that the condition is satisfied.

Abstract: There is provided a method for producing a mixed gas which contains a combustion assisting gas and a combustible gas characterized in that the method includes the steps of: (1) mixing a [combustion assisting gas and inert gas]-containing gas which contains the combustion assisting gas and an inert gas with the comestible gas so as to prepare a [combustion assisting gas, inert gas, and combustible gas]-containing gas which contains the combustion assisting gas, the inert gas, and the combustible gas; and (2) reducing an amount of the inert gas contained in the [combustion assisting gas, inert gas, and combustible gas]-containing gas. Such method is used for the production of a mix gas which further contains another combustible gas.

Abstract: The present invention provides an apparatus for producing an epoxy compound derived from an olefin by causing a reaction of hydrogen, oxygen, and the olefin in a liquid solvent in the presence of a catalyst in a reactor, wherein a vapor phase in the reactor contains an inert gas; hydrogen, an oxygen-containing gas with an oxygen concentration of at least 90% by volume, and the olefin are supplied to the vapor phase and/or liquid phase of the reactor to cause a reaction; and there exist a means for taking out the liquid phase containing the reaction product from the reactor.

Abstract: When a personal computer which implements an information processing apparatus according to this invention discovers communicable access points, the personal computer acquires pieces of information of the discovered access points. These pieces of information include, for example, the network name, communication speed, security level, communication channel, and radio field strength. A communication profile to be used by the personal computer is determined on the basis of these pieces of information, communication profiles set for the access points, and the priority of a communication profile to be used by the personal computer. A connection process between the personal computer and a wireless relay apparatus is automatically performed using the determined communication profile.