Patents by Inventor Ryo Kubota

Ryo Kubota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230144121
    Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.
    Type: Application
    Filed: January 11, 2023
    Publication date: May 11, 2023
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Karim HAROUD, Beat WYSS, Hans BERNHARD, Jean-Noel FEHR, Patrizia WEBER, Moritz HAEBERLI, Amitava GUPTA
  • Publication number: 20230118068
    Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retina. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.
    Type: Application
    Filed: December 16, 2022
    Publication date: April 20, 2023
    Applicant: ACUCELA INC.
    Inventors: Amitava GUPTA, Ryo KUBOTA
  • Patent number: 11627874
    Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: April 18, 2023
    Assignee: ACUCELA INC.
    Inventors: Lukas Scheibler, Matthias Pfister, Urban Schnell, Stefan Troller, Ryo Kubota
  • Patent number: 11630329
    Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: April 18, 2023
    Assignee: ACUCELA INC.
    Inventors: Ryo Kubota, Philip M. Buscemi, Pascal Loser, Ben Crook, Massimo Pinazza, Jim Niebanck, James Phillips, Stefan Bauer
  • Publication number: 20230110912
    Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
    Type: Application
    Filed: December 12, 2022
    Publication date: April 13, 2023
    Applicant: ACUCELA INC.
    Inventors: Christian OGGENFUSS, Karim HAROUD, Lukas SCHEIBLER, Matthias PFISTER, Urban SCHNELL, Stefan TROLLER, Ryo KUBOTA, Philip BUSCEMI
  • Patent number: 11624937
    Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retain. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: April 11, 2023
    Assignee: ACUCELA INC.
    Inventors: Amitava Gupta, Ryo Kubota
  • Patent number: 11619831
    Abstract: A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.
    Type: Grant
    Filed: June 10, 2022
    Date of Patent: April 4, 2023
    Assignee: ACUCELA INC.
    Inventors: Beat Wyss, Jean-Noël Fehr, Glenn Noronha, Karim Haroud, Julien Sauvet, Hans Bernhard, Christian Oggenfuss, Amitava Gupta, Ryo Kubota
  • Publication number: 20230089006
    Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.
    Type: Application
    Filed: November 1, 2022
    Publication date: March 23, 2023
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Gordon Frederick MACCABEE, Ferry WIDJAJA, Amitava GUPTA
  • Publication number: 20230063265
    Abstract: A contact lens charging case comprises a container sized and shaped to receive an electronic contact lens (“eCL”) and charging coil to couple to a coil of the eCL. In some embodiments, the charging coil comprises a diameter larger than a diameter of the coil of the eCL, so as to decrease sensitivity of the location and orientation of the eCL in the container and improve coupling between the coils. In some embodiments, the charging coil is dimensioned so as to extend at least partially around the container that receives the eCL.
    Type: Application
    Filed: February 19, 2021
    Publication date: March 2, 2023
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Patrizia WEBER, Marco BURGENER, Jonas BUTSCHER, Praveenth SANMUGARAJAH, Hans BERNHARD, Amitava GUPTA
  • Patent number: 11583696
    Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: February 21, 2023
    Assignee: ACUCELA INC.
    Inventors: Ryo Kubota, Karim Haroud, Beat Wyss, Hans Bernhard, Jean-Noël Fehr, Patrizia Weber, Moritz Haeberli, Amitava Gupta
  • Patent number: 11576572
    Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: February 14, 2023
    Assignee: ACUCELA INC.
    Inventors: Christian Oggenfuss, Karim Haroud, Lukas Scheibler, Matthias Pfister, Urban Schnell, Stefan Troller, Ryo Kubota, Philip M. Buscemi
  • Publication number: 20230026753
    Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
    Type: Application
    Filed: September 28, 2022
    Publication date: January 26, 2023
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Philip M. BUSCEMI, Matthias PFISTER, Stephan WYDER, Amitava GUPTA
  • Publication number: 20230026567
    Abstract: A stimulus is configured to treat astigmatism with changes in retinal thickness, independently of, or in combination with, treatment for myopia. In some embodiments, a stimulus pattern is arranged with respect to an astigmatic axis of the eye to decrease ocular growth in relation to the astigmatic axis. In some embodiments, the apparatus is configured to direct light to regions of retina outside the macula in relation to the astigmatic axis of the eye. In some embodiments, the intensity is modulated to provide the effect. A lens, such as a contact lens or spectacle lens may be configured with a plurality of light sources, such as projection units having a light source and focusing optics that work together to project anteriorly or posteriorly defocused images onto the retina at locations eccentric to the fovea.
    Type: Application
    Filed: September 28, 2022
    Publication date: January 26, 2023
    Applicant: ACUCELA INC.
    Inventors: Philip M. BUSCEMI, Ryo KUBOTA
  • Publication number: 20230020468
    Abstract: Improved optical coherence tomography systems and methods to measure retinal data are presented. The systems may be compact, provide in-home monitoring, and have automation to allow the patient to measure himself or herself.
    Type: Application
    Filed: September 2, 2020
    Publication date: January 19, 2023
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Philip M. BUSCEMI
  • Publication number: 20220413318
    Abstract: An apparatus to treat refractive error of the eye comprises one or more optics configured to project stimuli comprising out of focus images onto the peripheral retina outside the macula. While the stimuli can be configured in many ways, in some embodiments the stimuli are arranged to decrease interference with central vison such as macular vision. The stimuli can be out of focus images may comprise an amount of defocus within a range from about 3 Diopters (“D”) to about 6 D. In some embodiments, the brightness of the stimuli is greater than a brightness of background illumination by an appropriate amount such as at least 3 times the background brightness. In some embodiments, each of a plurality of stimuli comprises a spatial frequency distribution with an amplitude profile having spatial frequencies within a range from about range of 1×10?1 to 2.5×101 cycles per degree.
    Type: Application
    Filed: September 6, 2022
    Publication date: December 29, 2022
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Nabin JOSHI, Arkady SELENOW, Steven ALI, Stefan BAUER, Jean-Noel FEHR, Moritz HAEBERLI, Patrizia WEBER, Julien SAUVET, Amitava GUPTA
  • Publication number: 20220404641
    Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.
    Type: Application
    Filed: August 30, 2022
    Publication date: December 22, 2022
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Philip M. BUSCEMI, Amitava GUPTA, Stefan BAUER, Benjamin CROOK, Julien SAUVET
  • Publication number: 20220404638
    Abstract: Systems, devices, apparatuses and methods for an active projection system that may be incorporated into spectacles, contact lenses or provided as an add-on layer to existing spectacles or lenses. The active projection system operates to generate a stimulus or stimuli for viewing by a person's eye. The stimulus or stimuli creates an image that is defocused in front of the person's retina and can assist in slowing or stopping the progression of myopia or other refractive errors in the person.
    Type: Application
    Filed: August 18, 2022
    Publication date: December 22, 2022
    Applicant: ACUCELA INC.
    Inventors: Philip M. BUSCEMI, Ryo KUBOTA
  • Patent number: 11531216
    Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: December 20, 2022
    Assignee: ACUCELA INC.
    Inventors: Ryo Kubota, Gordon Frederick MacCabee, Ferry Widjaja, Amitava Gupta
  • Publication number: 20220390768
    Abstract: An apparatus to treat refractive error of an eye comprises an electroactive component configured to switch between a light scattering or optical power providing configuration to treat refractive error of the eye and a substantially transparent configuration to allow normal viewing. The electroactive component can be located on the lens away from a central axis of the lens to provide light to a peripheral region of the retina to decrease the progression of myopia. The electroactive component can be located on the lens away from the central axis of the lens in order for the wearer to view objects through an optical zone while the electroactive component scatters light. The electroactive component can be configured to switch to the substantially transparent configuration to allow light to pass through the electroactive component and to allow the lens to refract light to correct vision and allow normal viewing through the lens.
    Type: Application
    Filed: August 19, 2022
    Publication date: December 8, 2022
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Amitava GUPTA
  • Publication number: 20220390766
    Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.
    Type: Application
    Filed: August 17, 2022
    Publication date: December 8, 2022
    Applicant: ACUCELA INC.
    Inventors: Ryo KUBOTA, Philip M. BUSCEMI, Pascal LOSER, Ben CROOK, Massimo PINAZZA, Jim NIEBANCK, James PHILLIPS, Stefan BAUER