Patents by Inventor Ryo Yamahara

Ryo Yamahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190105412
    Abstract: The present invention provides a molecular assembly which is less likely to accumulate in tissue other than cancer tissue, is highly safe for a living body, and can be prepared by a simple and safe method and whose particle size can be easily controlled. The present invention provides a molecular imaging system and a molecular probe useful for the system, and a drug delivery system and a molecular probe useful for the system. The present invention provides a method for preparing molecular assembly, by which the particle size of molecular assembly having a signal group or a drug can be arbitrarily controlled in order to allow the molecular assembly to effectively accumulate in cancer tissue by utilizing EPR effect.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 11, 2019
    Applicant: SHIMADZU CORPORATION
    Inventors: Isao HARA, Ryo YAMAHARA, Eiichi OZEKI, Eri TAKEUCHI, Shunsaku KIMURA, Shinae KONDOH, Akira MAKINO, Fumihiko YAMAMOTO
  • Publication number: 20150031988
    Abstract: The present invention provides a therapeutic system that is widely applicable to general solid cancers, can achieve both a reduction in side effects of cancer therapy and suppression of cancer recurrence and metastasis, and requires no expensive drug such as an antibody; and a nanoparticle for internal radiation therapy. A system for internal radiation therapy of a vascular lesion site comprising: a device comprising a means for acquiring image data showing a position of a vascular lesion site, and a means for positioning a needle, which should be punctured into the vascular lesion site, at the vascular lesion site based on the image data; and a nanoparticle comprising an amphiphilic block polymer comprising a hydrophilic block having a sarcosine unit and a hydrophobic block having a lactic acid unit, and a substance labeled with a ?-ray emitting nuclide. The nanoparticle for internal radiation therapy.
    Type: Application
    Filed: September 12, 2012
    Publication date: January 29, 2015
    Inventors: Eri Takeuchi, Isao Hara, Ryo Yamahara, Eiichi Ozeki, Shunsaku Kimura, Kensuke Kurihara
  • Publication number: 20110104056
    Abstract: The present invention provides a molecular assembly which is less likely to accumulate in tissue other than cancer tissue, is highly safe for a living body, and can be prepared by a simple and safe method and whose particle size can be easily controlled. The present invention provides a molecular imaging system and a molecular probe useful for the system, and a drug delivery system and a molecular probe useful for the system. The present invention provides a method for preparing molecular assembly, by which the particle size of molecular assembly having a signal group or a drug can be arbitrarily controlled in order to allow the molecular assembly to effectively accumulate in cancer tissue by utilizing EPR effect.
    Type: Application
    Filed: June 4, 2009
    Publication date: May 5, 2011
    Inventors: Isao Hara, Ryo Yamahara, Eiichi Ozeki, Eri Takeuchi, Shunsaku Kimura, Shinae Kondoh, Akira Makino, Fumihiko Yamamoto
  • Publication number: 20100101943
    Abstract: A radioactive fluoride anion concentrating device capable of concentrating 18F? ions speedily and efficiently. A flow cell (11) is composed of a metal plate electrode (21), an insulating sheet (23) and a carbon plate electrode (25) located so that the sides of electrodes may be opposed to each other with the insulating sheet (23) inserted between them. An example of the plate metal plate electrode (21) is obtained by forming a film of metallic material on an insulation plate, and an example of the insulating sheet (23) is a PDMS from which a groove being a channel (26) having a thickness of ?500 ?m is cut out. The thickness of the sheet is desirably about 100 ?m. The upper and lower sides of the flow cell (11) are fixed by fixing jigs (27) and (29).
    Type: Application
    Filed: March 26, 2007
    Publication date: April 29, 2010
    Inventors: Ren Iwata, Eiichi Ozeki, Hiroaki Nakanishi, Katsumasa Sakamoto, Ryo Yamahara