Patents by Inventor Ryo YAMAUE

Ryo YAMAUE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RSV F/G CHIMERIC VACCINE
    Publication number: 20220111035
    Abstract: A novel vaccine antigen for prevention of Respiratory Syncytial Virus (RSV) infection is created which surpasses conventional vaccines comprising as an antigen RSV F protein alone in view of efficacy and/or safety. A vaccine is prepared which comprises as an antigen a RSV F/G chimeric protein wherein a portion of RSV F protein as a basic structure is replaced with a whole or a portion of Conserved Central Domain sequence of RSV G protein or wherein a whole or a portion of Conserved Central Domain sequence of RSV G is added to the basic structure. As a result of assessment of both efficacy and safety, a vaccine comprising as an antigen the F/G chimeric protein of the present invention confirmed to be more excellent than a vaccine comprising as an antigen RSV F protein alone in view of efficacy and/or safety.
    Type: Application
    Filed: February 27, 2020
    Publication date: April 14, 2022
    Applicant: KM Biologics Co., Ltd.
    Inventors: Ryo YAMAUE, Satoshi KAMAKURA, Mihoko MATSUO, Masaharu TORIKAI, Hiroaki MORI
  • Vaccine containing immobilized virus particles
    Patent number: 10881723
    Abstract: The present invention relates to a vaccine containing fixed virus particles, wherein a summed fever response of three rabbits to the fixed virus particles in a pyrogen test is less than 80% based on a summed fever response of three rabbits to original virus particles of the fixed virus particles or corresponding inactivated virus particles.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: January 5, 2021
    Assignee: KM BIOLOGICS CO., LTD.
    Inventors: Hiroto Onuma, Yukari Tsurudome, Kazuyuki Ikeda, Ryo Yamaue, Kazuhiko Kimachi, Motoharu Abe, Akihiro Watanabe, Yuki Ohara
  • VACCINE CONTAINING IMMOBILIZED VIRUS PARTICLES
    Publication number: 20190000960
    Abstract: The present invention relates to a vaccine containing fixed virus particles, wherein a summed fever response of three rabbits to the fixed virus particles in a pyrogen test is less than 80% based on a summed fever response of three rabbits to original virus particles of the fixed virus particles or corresponding inactivated virus particles.
    Type: Application
    Filed: January 10, 2017
    Publication date: January 3, 2019
    Inventors: Hiroto ONUMA, Yukari TSURUDOME, Kazuyuki IKEDA, Ryo YAMAUE, Kazuhiko KIMACHI, Motoharu ABE, Akihiro WATANABE, Yuki OHARA