Abstract: An objective of the present invention is to provide a measuring chip for a surface plasmon resonance sensor that can detect a small amount of target substances in high sensitivity. The present invention provides a measuring chip for a surface plasmon resonance sensor comprising a metal layer, one or more plasma polymerization layers formed on said metal layer, and a biologically active substance immobilized on the surface of said plasma polymerization layer.

Abstract: An objective of the present invention is to provide a measuring chip for a surface plasmon resonance sensor that can detect a small amount of target substances in high sensitivity. The present invention provides a measuring chip for a surface plasmon resonance sensor comprising a metal layer, one or more plasma polymerization layers formed on said metal layer, and a biologically active substance immobilized on the surface of said plasma polymerization layer.

Abstract: An objective of the present invention is to provide a measuring chip for a surface plasmon resonance sensor that can detect a small amount of target substances in high sensitivity. The present invention provides a measuring chip for a surface plasmon resonance sensor comprising a metal layer, one or more plasma polymerization layers formed on said metal layer, and a biologically active substance immobilized on the surface of said plasma polymerization layer.

Abstract: An object of the present invention is to provide a method for detecting a target nucleotide sequence using the hybridization method, which has a remarkably improved sensitivity of detection. The method comprises the steps of hybridizing a target nucleotide sequence with a PNA that is complementary to the whole or a part of the target nucleotide sequence and measuring the degree of hybridization at the presence of a denaturing agent.

Abstract: An object of the present invention is to provide a method for detecting a target nucleotide sequence using a complementary nucleotide sequence that has an excellent sensitivity of detection. The method comprises the steps of converting the target nucleotide sequence to a partially double-stranded nucleotide sequence which is double-stranded at one part and single-stranded in the remaining part and detecting said partially double stranded nucleotide sequence using a nucleotide sequence that is complementary to the target nucleotide sequence.

Abstract: An object of the present invention is to provide a method for detecting a target nucleotide sequence using a complementary nucleotide sequence that has an excellent sensitivity of detection. The method comprises the steps of converting the target nucleotide sequence to a partially double-stranded nucleotide sequence which is double-stranded at one part and single-stranded in the remaining part and detecting said partially double stranded nucleotide sequence using a nucleotide sequence that is complementary to the target nucleotide sequence.

Abstract: A measuring chip for an optical analyzer includes a translucent or transparent substrate 1, and a sample solution chamber S formed on a sulface of the translucent or transparent substrate 1. The sample solution chamber S has an inlet S.sub.1 for introducing a sample solution to be analyzed, and an outlet S.sub.2 for discharging the analyzed sample solution. The sample solution chamber S is formed so as to be filled with the sample solution between the inlet S.sub.1 and the vicinity of the outlet S.sub.2 by the capillary phenomenon. On the translucent or transparent substrate 1, an analyzing region 10 is formed by stacking a metal thin film 2 and an immobilizing film 3 for immobilizing a physiologically active substance 4. On the analyzing region 10, the sample solution chamber S is formed to obtain a measuring chip for an optical analyzer particularly utilizing the surface plasmon resonance (SPR). Thus.

Abstract: An enzyme sensor system capable of quantitatively determining a particular component contained in a biological sample in a rapid and easy manner is disclosed. More particularly, an electrically conductive enzyme, an enzyme-immobilized electrode using the same and a composition for use in the preparation of the enzyme electrode are disclosed. The composition for an enzyme-immobilized electrode according to the present invention enables electrodes of various patterns to be produced by screen printing.

Abstract: A water-disintegrable support paper material largely formed of fibrous carboxymethylcellulose or carboxyethylcellulose having a degree of etherification of 0.1 to 1.0 and a degree of base saturation of 20% or more. A solution or dispersion of that paper has a pH of 5.0 to 8.0. There is also disclosed a composition for forming a water-disintegrable coat for coating on the support, the composition being a mixture of (a) at least one water-insoluble resin capable of forming a film having a saturation hygroscopicity less than 15% at a 90% relative humidity, (b) at least one water-soluble resin capable of forming film having a saturation hygroscopicity of 15% or more at a 90% relative humidity, and (c) a solvent in which both the resins (a) and (b) can dissolve.