Patents by Inventor Ryohei TOGASHI

Ryohei TOGASHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220280418
    Abstract: Provided is a means that is capable of preventing initial excessive release of an active ingredient and that allows for sustained release of the active ingredient in a pharmaceutically active amount over a long period of time.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 8, 2022
    Applicant: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Motoyasu YOSHIMURA, Takuya FUJII, Naoki KAMADA, Ryohei TOGASHI, Ryuta AONO, Xinyu WANG
  • Publication number: 20220273647
    Abstract: Provided is a means that is capable of preventing initial excessive release of an active ingredient and that allows for sustained release of the active ingredient in a pharmaceutically active amount over a long period of time.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 1, 2022
    Applicant: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Motoyasu YOSHIMURA, Takuya FUJII, Naoki KAMADA, Ryohei TOGASHI, Ryuta AONO, Xinyu WANG
  • Patent number: 10385030
    Abstract: The present invention aims to provide a cationic lipid that can be used as a nucleic acid delivery carrier, a lipid membrane structure using a cationic lipid, a nucleic acid-introducing agent using a cationic lipid, and a method of achieving nucleic acid introduction by using a nucleic acid-introducing agent containing a cationic lipid. A lipid membrane structure containing a cationic lipid represented by the formula (1) wherein each symbol is as defined in the DESCRIPTION, is superior in the stability in blood and tumor accumulation property. A nucleic acid-introducing agent using the cationic lipid can achieve high nucleic acid delivery efficiency of nucleic acid to be delivered into the cytoplasm.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: August 20, 2019
    Assignees: NOF CORPORATION, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuta Nakai, Kota Tange, Hidetaka Akita, Hideyoshi Harashima, Ryohei Togashi, Naoya Miura, Mio Maeta
  • Publication number: 20180155304
    Abstract: The present invention aims to provide a cationic lipid that can be used as a nucleic acid delivery carrier, a lipid membrane structure using a cationic lipid, a nucleic acid-introducing agent using a cationic lipid, and a method of achieving nucleic acid introduction by using a nucleic acid-introducing agent containing a cationic lipid. A lipid membrane structure containing a cationic lipid represented by the formula (1) wherein each symbol is as defined in the DESCRIPTION, is superior in the stability in blood and tumor accumulation property. A nucleic acid-introducing agent using the cationic lipid can achieve high nucleic acid delivery efficiency of nucleic acid to be delivered into the cytoplasm.
    Type: Application
    Filed: January 29, 2016
    Publication date: June 7, 2018
    Applicants: NOF CORPORATION, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuta NAKAI, Kota TANGE, Hidetaka AKITA, Hideyoshi HARASHIMA, Ryohei TOGASHI, Naoya MIURA, Mio MAETA